Interleukin-6 wani nau'in polypeptide ne wanda ya ƙunshi sarƙoƙi biyu na glycoprotein, waɗanda ke da nauyin kwayoyin halitta na 130kd. A matsayinsa na memba mai mahimmanci a cikin hanyar sadarwar cytokine, interleukin-6 (IL-6) yana taka muhimmiyar rawa a cikin amsawar kumburi mai tsanani, kuma yana iya daidaita amsawar lokaci mai tsanani na hanta, da kuma haɓaka samar da furotin C-reactive (CRP) da fibrinogen. Cututtuka da yawa masu yaɗuwa na iya haifar da ƙaruwa a matakin IL-6 a cikin jini, kuma matakin IL-6 yana da alaƙa da sakamakon marasa lafiya. A matsayin cytokine na pleiotropic tare da ayyuka masu yawa, IL-6 yana fitowa ta hanyar ƙwayoyin T, ƙwayoyin B, ƙwayoyin mononuclear phagocyte, da ƙwayoyin endothelial, kuma muhimmin ɓangare ne na hanyar sadarwa ta mai shiga tsakani na kumburi. Da zarar amsawar kumburi ta faru, IL-6's suna farawa, wanda ke haifar da samar da CRP da procalcitonin (PCT) bayan samarwa. Za a samar da shi cikin sauri idan akwai kamuwa da cuta, raunuka na ciki da na waje, tiyata, amsawar damuwa, mutuwar kwakwalwa, tumorigenesis, da tsarin amsawar kumburi mai tsanani na wasu yanayi. IL-6 yana da hannu wajen kamuwa da cututtuka da dama, matakin jininsa yana da alaƙa da kumburi, kamuwa da ƙwayoyin cuta da cututtukan da ke shafar garkuwar jiki, kuma canje-canjensa suna faruwa ne kafin CRP. A cewar sakamakon bincike, matakin IL-6 yana ƙaruwa da sauri bayan kamuwa da ƙwayoyin cuta, matakin PCT yana ƙaruwa bayan sa'o'i 2, yayin da CRP ke ƙaruwa da sauri bayan sa'o'i 6. Fitar da ƙwayoyin cuta ko bayyanar kwayoyin halitta na IL-6 na iya haifar da kamuwa da cututtuka iri-iri, ana iya fitar da adadi mai yawa na IL-6 cikin zagayawar jini a yanayin rashin lafiya, kuma gano IL-6 yana da matuƙar muhimmanci ga ganewar cututtuka da kuma yanke hukunci game da hasashensu.