Nasarar Gwajin Mara Cin Hanci:Calprotectin"Yankan Ketare" don Taimakawa Binciken Farko na Ciwon GI na Sama a Yara

A fagen bincikar cututtukan cututtukan cututtukan cututtukan cututtukan yara, endoscopy ya daɗe shine "ma'aunin zinare" don ƙayyade kumburin ciki na sama. Duk da haka, wannan jarrabawa na cin zarafi ba wai kawai yana tare da rashin jin daɗi na jiki ga yara ba, musamman ma matasa, amma kuma sau da yawa yana kawo babban tsoro na tunani da wahala wajen haɗin gwiwa. Wannan yana sa iyaye da yawa su yi shakka a lokacin ganewar asali na farko kuma yana iya rasa damar da za a fara shiga tsakani. Kwanan nan, sabon bincike na asibiti da aikace-aikacen aikace-aikacen ya kawo labarai masu ban sha'awa:Fecal calprotectin (FCP), Alamar balagagge ba mai haɗari ba don kima na ƙananan cututtuka na gastrointestinal fili, yana nuna babban tasiri a farkon ganewar asali na kumburi na ciki na sama a cikin yara, samun nasara mai ban mamaki "crossover" daga "ƙananan hanji" zuwa "babban hanji".

Daga Dilemma na "Ma'aunin Zinariya" zuwa Alfijir na Gwajin Rashin Cin Hanci

Ciwon ciki na sama kamar gastroduodenitis da gastroduodenitis ba bakon abu ba ne a cikin yara, kuma abubuwan da ke haifar da su sun haɗa da kamuwa da cuta, magunguna, da halayen damuwa. A al'adance, ganewar asali yana buƙatar kallon gani da kuma biopsy nama ta hanyar gastroscopy, wanda shine tsari mai rikitarwa da ɓarna. Hanyoyin da ba su da haɗari kuma masu dacewa sun kasance koyaushe abin da ake tsammani na likitoci da iyalan yara masu cutar.Calprotectinfurotin ne wanda ke nuna tarawar neutrophil. Lokacin da mucosa na ciki ya ƙone, maida hankali zai karu sosai. A cikin shekarun da suka wuce, an yi amfani da shi sosai a cikin ƙididdigar ayyuka na cututtukan cututtuka na ƙwayar cuta (IBD) da kuma bambancin ganewar ciwon ciwon hanji (IBS), musamman don kumburin hanji.

Bincike na kimiyya ya tabbatar da ingantaccen tushe don aikace-aikacen "ƙetare iyaka".

Wani ci gaba na bincike ya nuna cewa wannan alamar kumburi ba ta keɓanta ga hanji ba. Lokacin da kumburi mai aiki ya faru a cikin sashin gastrointestinal na sama (kamar ciki da duodenum), sel masu kumburi suma suna kutsawa kuma suna saki.calprotectin. Wannan sunadaran yana tafiya a cikin hanyar narkewa tare da ruwa mai narkewa da ragowar abinci, a ƙarshe ana gano shi a cikin stool. Nazarin kwanan nan akan yara ya nuna hakancalprotectinMatakan sun fi girma a cikin yara tare da endoscopically tabbatar da gastritis ko duodenitis idan aka kwatanta da wadanda ke da dyspepsia na aiki ko kuma binciken endoscopic na al'ada.Ko da yake matakan FC masu girma da suka haifar da kumburi na ciki na ciki suna da ƙasa fiye da waɗanda ke cikin IBD mai aiki, sun nuna bambance-bambance masu mahimmanci idan aka kwatanta da mutane masu lafiya. Wannan yana nuna cewa za'a iya amfani da gwajin FC azaman kayan aiki mai inganci don taimakawa likitoci da farko gano yara da ke cikin haɗarin ƙwayoyin cuta na kumburin gastrointestinal a cikin adadi mai yawa na yaran da ke nuna alamun kamar ciwon ciki, kumburin ciki, da tashin zuciya.

Ƙimar Clinical: Gina Ingantacciyar Tafarkin Bincike na Yara

Aikace-aikacen kan iyaka nacalprotectinya kawo fa'idodi da yawa ga ganewar asali da kula da cututtukan gastrointestinal na sama a cikin yara:

1.Non-invasive and high compliance: Ana buƙatar ƙananan samfurin stool kawai, kuma tsarin ba shi da kullun, wanda ya rage nauyin jiki da tunani akan yara. Iyaye suna yarda da tsarin sosai, yana sauƙaƙa saurin gudanar da sa ido akai-akai a asibitocin waje.
2. Ingantacciyar tantancewa da kayan aiki: Ga yara masu ci gaba da bayyanar cututtuka na ciki,Calprotectinza a iya yin gwaji da farko don bambanta daidai tsakanin cututtuka masu kumburi da aiki. IdanCalprotectinmatakan al'ada ne, ana iya ba da fifikon abubuwan aiki ko jiyya mai ƙarfi kuma ana iya ɗaukar lura. Idan an haɓaka matakan FC, yana ba da tushe mai ƙarfi don gastroscopy mai ɓarna, guje wa hanyoyin endoscopic mara amfani da haɓaka rabon albarkatun likita.
3. Taimakawa kimantawa na inganci da sake dawowa: Bayan ganewar asali na kumburi na gastrointestinal babba da kuma fara jiyya, saka idanu mai ƙarfi na canje-canje a cikinCalprotectinMatakan na iya zama alamar maƙasudi na haƙiƙa don kimanta ko kumburin ya ragu kuma ko magani yana da tasiri. Hakanan zai iya taimakawa wajen gano cutar da wuri.

Gaban Outlook

Tabbas, aikace-aikacen calprotectin na fecal a cikin sashin gastrointestinal na sama har yanzu yana buƙatar ƙarin bincike don ƙayyadadden ƙimar yankewa mafi kyau kuma ya fitar da wasu ƙananan abubuwan ciki na ciki waɗanda zasu iya haifar da haɓakar FC. Duk da haka, a matsayin hanya mai aminci, mai sauƙi, da ƙananan farashi, babu shakka yana buɗe sabuwar kofa don ganewar asali na ciwon ciki na sama a cikin yara. Yana nuna alamar ci gaba a cikin gano cututtukan cututtukan ƙwayar cuta na yara zuwa mafi kyawun ɗan adam da madaidaicin hanya. Mun yi imanin cewa tare da ci gaba da bincike mai zurfi da kuma tarin ƙwarewar asibiti,calprotectin,wannan “tauraron ƙetarewa,” zai ƙara taka muhimmiyar rawa wajen kare lafiyar yara masu narkewa.

Baysen Medical koyaushe yana mai da hankali kan dabarun bincike don haɓaka ingancin rayuwa. Mun ɓullo da 5 fasaha dandamali- Latex , colloidal zinariya , Fluorescence Immunochromatographic Assay , Molecular, Chemiluminescence Immunoassay.Muna da Colloidal GoldCalprotectin kayan gwaji da Fluorescence ImmunoassayKayan gwajin Calprotectindomin gwaji