Ferritin: Ma'auni mai sauri kuma daidaitaccen ma'aunin halitta don tantance ƙarancin ƙarfe da anemia

Gabatarwa

Karancin ƙarfe da anemia matsalolin kiwon lafiya ne da ya zama ruwan dare gama gari a duniya, musamman a ƙasashe masu tasowa, mata masu juna biyu, yara da matan da suka kai shekarun haihuwa. Rashin ƙarancin ƙarfe (IDA) ba wai kawai yana rinjayar aikin jiki da tunani na daidaikun mutane ba, amma yana iya ƙara haɗarin rikice-rikice na ciki da jinkirin ci gaba a cikin yara. Don haka, yin gwajin farko da sa baki suna da mahimmanci. Daga cikin alamomin ganowa da yawa, ferritin ya zama kayan aiki mai mahimmanci don tantance ƙarancin ƙarfe da anemia saboda girman hankali da ƙayyadaddun sa. Wannan labarin zai tattauna halayen ilimin halitta na ferritin, fa'idodinsa a cikin ganewar asali na ƙarancin ƙarfe da anemia, da ƙimar aikace-aikacen asibiti.

Halayen Halittu naFerritin

Ferritinfurotin ne na ajiyar ƙarfe da ke da yawa a cikin kyallen jikin ɗan adam. Hanta, saifa da kasusuwan kasusuwa ne ke hada shi. Babban aikinsa shine adana ƙarfe da daidaita ma'aunin ƙarfe na ƙarfe. A cikin jini, maida hankali naferritinyana da alaƙa da gaske tare da ajiyar ƙarfe na jiki. Saboda haka, serumferritinMatakan suna ɗaya daga cikin mafi mahimmancin alamun yanayin ajiyar ƙarfe na jiki. A karkashin yanayi na al'ada, matakin ferritin a cikin maza masu girma yana kusan 30-400 ng / ml, kuma a cikin mata yana da 15-150 ng / ml, amma a yanayin rashin ƙarfe, wannan darajar za ta ragu sosai.

AmfaninFerritina cikin Binciken Rashin Ƙarfe

1. Babban hankali, farkon gano ƙarancin ƙarfe

Ci gaban ƙarancin ƙarfe ya kasu kashi uku:

• Matakin ƙarancin ƙarfe: ƙarfen ajiya(faritin) yana raguwa, amma haemoglobin al'ada ne;
• Rashin ƙarfe erythropoiesis mataki:ferritinkara raguwa, transferrin jikewa yana raguwa;
• Matsayin ƙarancin ƙarfe na anemia matakin: haemoglobin yana raguwa, kuma alamun anemia na yau da kullun suna bayyana.

Hanyoyin nunawa na al'ada (kamar gwajin haemoglobin) na iya gano matsaloli a matakin anemia, yayin daferritingwaje-gwaje na iya gano abubuwan da ba su da kyau a farkon matakin ƙarancin ƙarfe, don haka ba da damar shiga tsakani da wuri.

2. Babban Takamaiman, Rage Rashin Bincike

Cututtuka da yawa (kamar kumburin kumburi da kamuwa da cuta) na iya haifar da anemia, amma ba ƙarancin ƙarfe ke haifar da su ba. A wannan yanayin, dogaro kawai da haemoglobin ko ma'anar ƙarar jiki (MCV) na iya kuskuren dalilin.FerritinGwaji na iya bambanta ƙarancin ƙarancin ƙarfe daidai da sauran nau'ikan anemia (kamar anemia na cututtuka na yau da kullun), haɓaka daidaiton bincike.

3. Mai sauri da dacewa, dace da babban sikelin nunawa

Fasahar gwajin sinadarai ta zamani tana sa ƙudirin ferritin cikin sauri da tattalin arziki, kuma ya dace da ayyukan kiwon lafiyar jama'a kamar tantancewar al'umma, kula da lafiyar mata da jarirai, da kula da abinci mai gina jiki na yara. Idan aka kwatanta da gwaje-gwaje masu cin zarafi kamar tabon baƙin ƙarfe na kasusuwa (misali na zinariya), gwajin jini na ferritin ya fi sauƙi don haɓakawa.

Aikace-aikacen asibiti na Ferritin a Gudanar da Anemia

1. Jagoran maganin karin ƙarfe

FerritinMatakan na iya taimaka wa likitoci su tantance ko marasa lafiya suna buƙatar ƙarin ƙarfe da kuma lura da tasirin jiyya. Misali:

• Ferritin<30 ng/mL: yana nuna cewa ajiyar ƙarfe ya ƙare kuma ana buƙatar ƙarin ƙarfe;
• Ferritin<15 ng/mL: yana nuna ƙarfi da ƙarfi anemia rashi baƙin ƙarfe;
• Lokacin da magani ya yi tasiri, ferritin matakan za su tashi a hankali kuma ana iya amfani da su don kimanta ingancin

1. Jagoran Kariyar Ƙarfe

Ferritinmatakan suna taimaka wa likitocin likita don sanin buƙatar maganin ƙarfe da kuma lura da ingancin magani. Misali:

• Ferritin<30 ng/mL: Yana nuna shagunan ƙarfe da aka ƙare, suna buƙatar kari.
• Ferritin<15 ng/mL: Ƙarfin yana ba da shawarar ƙarancin ƙarfe anemia.
• A lokacin jiyya, tashiferritinmatakan tabbatar da tasirin warkewa.

2. Nuna yawan jama'a na musamman

• Mata masu ciki: bukatar baƙin ƙarfe yana ƙaruwa yayin daukar ciki, daferritingwaje-gwaje na iya hana rikitarwa masu juna biyu da jarirai.
• Yara: Rashin ƙarancin ƙarfe yana rinjayar ci gaban fahimi, kuma gwajin farko na iya inganta tsinkaye.
• Marasa lafiya da cututtuka na yau da kullun: kamar marasa lafiya da cututtukan koda da cututtukan hanji mai kumburi,ferritin hade tare da transferrin jikewa zai iya gane nau'in anemia.

Iyakance naFerritinGwaji da Magani

Kodayake ferritin shine alamar da aka fi so don tantance ƙarancin ƙarfe, yana buƙatar fassara shi da taka tsantsan a wasu lokuta:

• Kumburi ko kamuwa da cuta:Ferritin, a matsayin wani m lokaci reactant furotin, za a iya karya karya daga cikin kamuwa da cuta, ƙari ko kullum kumburi. A wannan yanayin, ana iya haɗa shi tare daC-reactive protein (CRP) ortransferrinjikewa don cikakken hukunci.
• Cutar hanta:Ferritina cikin marasa lafiya tare da cirrhosis na iya karuwa saboda lalacewar hanta kuma yana buƙatar kimantawa a hade tare da sauran alamun metabolism na baƙin ƙarfe.

Kammalawa

Ferritingwaji ya zama kayan aiki mai mahimmanci don tantance ƙarancin ƙarfe da anemia saboda yawan hankalinsa, ƙayyadaddun da kuma dacewa. Ba wai kawai zai iya gano ƙarancin ƙarfe da wuri ba kuma ya guje wa ci gaban anemia, amma kuma yana jagorantar madaidaicin jiyya da haɓaka hasashen haƙuri. A cikin lafiyar jama'a da aikin asibiti, haɓakawa naferritin gwaje-gwaje na iya taimakawa wajen rage nauyin cututtuka na karancin ƙarfe na anemia, musamman ga ƙungiyoyi masu haɗari (kamar mata masu ciki, yara da marasa lafiya masu fama da cututtuka). A nan gaba, tare da ci gaban fasahar ganowa.ferritin na iya taka rawa sosai wajen rigakafin anemia a duniya.

Mu Baysen Medical koyaushe yana mai da hankali kan dabarun bincike don haɓaka ingancin rayuwa. Mun ɓullo da 5 fasaha dandamali- Latex, colloidal zinariya, Fluorescence Immunochromatographic Assay, Kwayoyin, Chemiluminescence Immunoassay, OurKayan gwajin Ferritin aiki mai sauƙi kuma yana iya samun sakamakon gwaji a cikin mintuna 15