Troponin T na Cardiac (cTnT), wani yanki ne na hadaddun troponin da aka bayyana musamman a cikin ƙwayoyin halittar zuciya, yana tsaye a matsayin ɗaya daga cikin alamomin da suka fi canzawa kuma ba makawa a cikin maganin cututtukan zuciya na zamani. Muhimmancinsa ya samo asali ne daga keɓancewarsa ta musamman a cikin zuciya, babban ƙarfinsa, da kuma babban rawar da yake takawa wajen gano cutar, rarraba haɗari, da kuma kula da cututtukan zuciya masu tsanani (ACS) da sauran raunukan zuciya.

Mafi mahimmanci, cTnT shine babban alamar gano cutar bugun zuciya (MI). Kafin a ɗauki troponin, ganewar asali ya dogara ne akan alamun da ba su da takamaiman takamaiman kamar Creatine Kinase-MB (CK-MB) da alamun asibiti, wanda ke haifar da rashin tabbas na ganewar asali. Sakin cTnT cikin jini bayan cutar sankarar zuciya ya kasance musamman ga lalacewar tsokar zuciya. Zuwan gwaje-gwajen troponin T (hs-cTnT) mai yawan ji na ƙwarai ya ƙara kawo sauyi a wannan fanni. Waɗannan gwaje-gwajen na iya gano ƙaramin ƙaruwa na cTnT ƙasa da iyakar kashi 99 na sama na yawan jama'a. Wannan yana bawa likitoci damar gano raunin zuciya tun da wuri - sau da yawa cikin awanni 1-3 bayan gabatarwar sashen gaggawa - yana ba da damar yin sauri da kuma, mafi mahimmanci, mafi sauri da tabbaci cire MI. Wannan yana hanzarta magani don ingantattun sakamako kuma yana kwantar da marasa lafiya marasa haɗari lafiya, yana inganta ingancin sashen gaggawa da kwararar marasa lafiya.

Bayan ganewar asali, cTnT tana taka muhimmiyar rawa wajen rarraba haɗari da kuma hasashen faruwar haɗari. Girman hauhawar cTnT yana da alaƙa sosai da girman lalacewar zuciya kuma yana da ƙarfin hasashen sakamako masu illa na ɗan gajeren lokaci da na dogon lokaci, gami da gazawar zuciya, bugun zuciya mai maimaitawa, da mace-mace. Ko da ƙananan hauhawar jini na yau da kullun da aka gano ta hanyar gwaje-gwajen hs-cTnT a cikin marasa lafiya da suka yi kama da marasa lafiya na iya gano waɗanda ke da raunin zuciya, yana nuna babban haɗarin abubuwan da ke faruwa na zuciya a nan gaba. Wannan ya sa cTnT kayan aiki mai mahimmanci ba wai kawai a cikin yanayi mai tsanani ba har ma a cikin kula da yanayi na yau da kullun kamar cututtukan jijiyoyin zuciya masu ƙarfi, gazawar zuciya, da cututtukan koda na yau da kullun.

Bugu da ƙari, ma'aunin cTnT yana jagorantar yanke shawara mai mahimmanci game da magani. Tsarin ƙaruwa da/ko raguwa na cTnT yana da mahimmanci don ayyana MI mai tsanani bisa ga jagororin duniya. Wannan tabbacin biochemical yana sanar da kai tsaye ga hanyoyin gaggawa kamar su angiography na zuciya da sake fasalin jijiyoyin jini (PCI ko CABG). Hakanan yana taimakawa wajen zaɓar da sa ido kan ingancin magungunan magunguna, gami da magungunan hana platelet masu ƙarfi (misali, ticagrelor, prasugrel) da magungunan hana ɗaukar jini.

Muhimmancin cTnT ya shafi cututtukan zuciya marasa ischemic. Ana ganin ƙaruwar matakan a cikin cututtuka daban-daban inda bugun zuciya ko rauni ya faru, kamar myocarditis, rauni na zuciya, mummunan sepsis, embolism na huhu wanda ke haifar da bugun zuciya na dama, da kuma gubar zuciya da ke da alaƙa da chemotherapy. A cikin waɗannan yanayi, cTnT yana aiki a matsayin alamar da ke nuna cewa zuciya ta shiga cikin matsala, yana haifar da ƙarin bincike da kuma kulawa ta musamman.

A ƙarshe, Cardiac Troponin T ya sake fasalin aikin zuciya. Juyin halittarsa ​​zuwa gwajin ƙarfin jijiyoyi ya ƙarfafa matsayinsa a matsayin babban alamar cutar raunin zuciya. Ta hanyar samar da daidaiton ganewar asali mara misaltuwa, bayanai masu ƙarfi na hasashen yanayi, da kuma jagora mai mahimmanci don hanyoyin magance matsalolin ceton rai, cTnT yana da mahimmanci don inganta sakamakon marasa lafiya a cikin gaggawa na zuciya da jijiyoyin jini da kuma kula da cututtukan zuciya na dogon lokaci. Ma'auninsa ba shi da wani tasiri a cikin kulawar zuciya ta zamani.