Introduction: ʻO ke koʻikoʻi o ke kino o ka nānā ʻana i ka hana o ka renal mua:

Ua lilo ka ma'i ma'i ma'i ma'i (CKD) i mea pa'akikī no ka lehulehu. Wahi a ka ʻikepili mai ka World Health Organization, ma kahi o 850 miliona mau kānaka ma ka honua holoʻokoʻa e loaʻa i nā maʻi maʻi ʻē aʻe, a ʻo ka nui o ka maʻi maʻi maʻi maʻi ma kahi o 9.1%. ʻO ka mea ʻoi aku ka koʻikoʻi, ʻo ka loaʻa ʻole o nā hōʻailona ʻike ʻia o ka maʻi maʻi maʻi maʻi maʻamau, e hōʻemi ana i ka nui o nā maʻi i ka manawa maikaʻi loa no ka hana. Kūʻē i kēia kāʻei kua,microalbuminuria, ma ke ʻano he hōʻailona koʻikoʻi o ka pōʻino o ka puʻupaʻa mua, ua lilo i mea waiwai. ʻO nā ʻano hana hoʻāʻo hana renal kuʻuna e like me ka serum creatinine a me ka helu ʻana o ka glomerular filtration rate (eGFR) e hōʻike wale i nā mea ʻino ke nalowale ka hana renal ma mua o 50%, ʻoiai ʻo ka hoʻāʻo ʻana i ka albumin mimi hiki ke hāʻawi i nā hōʻailona hōʻailona mua ke nalowale ka hana renal e 10-15%.

ʻO ka waiwai lapaʻau a me ke kūlana o kēia manawa oALBhōʻike mimi

Albumin (ALB) ʻo ia ka protein nui loa i ka mimi o nā kānaka olakino, me ka helu excretion maʻamau ma lalo o 30mg/24h. I ka wā o ka urinary albumin excretion rate i loko o ka laulā o 30-300mg / 24h, ua wehewehe ʻia ʻo ia he microalbuminuria, a ʻo kēia kaʻina ka manawa puka aniani gula no ka hana ʻana e hoʻohuli i ka pōʻino o ke kīkī. I kēia manawa, hoʻohana pinepine ʻiaALBʻO nā ʻano hana ʻike i ka hana lapaʻau e pili ana i ka radioimmunoassay, enzyme-linked immunosorbent assay (ELISA), immunoturbidimetry, a me nā mea ʻē aʻe. Maikaʻi no nā keʻena lapaʻau mua a me nā hiʻohiʻona nānā home, paʻakikī nā ʻenehana i kēia manawa e hoʻokō i nā pono o ka maʻalahi, ka wikiwiki, a me ka pololei, ka hopena o ka nui o nā maʻi me ka pōʻino o ka puʻupaʻa mua ʻaʻole i ʻike ʻia i ka manawa.

Nā Kūlana Hou i ka pololeiHoao ALB mimiReagent

I ka pane ʻana i nā palena o ka ʻenehana hoʻāʻo e kū nei, ua hoʻomohala kā mākou hui i ka PrecisionHoao ALB mimi Reagent e hoʻomaopopo i ka nui o ka ʻenehana holomua. Hoʻohana ka reagent i ka ʻenehana immunochromatographic kiʻekiʻe me ka pilina kiʻekiʻe a me ke kikoʻī kiʻekiʻe anti-human albumin monoclonal antibody e hōʻoia i ka pololei a me ka hilinaʻi o ka hoʻāʻo. Hōʻike nui ʻia ka ʻenehana loea i ʻekolu mau ʻano:

• Ua hoʻomaikaʻi maikaʻi ʻia ka ʻike: hiki i ka palena haʻahaʻa o ka ʻike ʻana i ka 2mg/L, a hiki iā ia ke ʻike pono i ka paepae mimi o microalbumin o 30mg/24h, ʻoi aku ka maikaʻi ma mua o ka naʻau o nā ʻāpana hoʻāʻo kuʻuna.
• Hoʻonui i ka mana anti-interference: Ma o ka hoʻolālā ʻōnaehana buffer kūʻokoʻa, hiki iā ia ke lanakila i ka hoʻopili ʻana o ka urine pH fluctuations, hoʻololi ikaika ionic a me nā mea ʻē aʻe i nā hopena hōʻike, e hōʻoiaʻiʻo ana i ka paʻa o ka hoʻokolohua ma lalo o nā kūlana physiological like ʻole.
• ʻO ka ʻike nui ʻana: hiki i ka mea heluhelu kūikawā kākoʻo ke hoʻomaopopo i ka semi-quantitative a i ka quantitative detection, uhi ʻia ka pae ʻike i ka 0-200mg/L, e hoʻokō i nā pono lapaʻau like ʻole mai ka nānā ʻana i ka nānā ʻana.

Hana Hana a me nā Pono

Hoʻopaʻa ʻia i ka maʻi maʻi i kekahi mau haukapila tertiary, hōʻike kēia reagent i nā hōʻailona hana maikaʻi loa. Ke hoʻohālikelike ʻia me ke gula maʻamau 24-hola urine albumin quantification, ʻoi aku ka coefficient correlation ma mua o 0.98; ʻoi aku ka liʻiliʻi o nā coefficients intra-a me inter-batch o ka hoʻololi ʻana ma mua o 5%, ʻoi aku ka haʻahaʻa ma mua o ke kūlana ʻoihana; ʻO ka manawa ʻike he 15 mau minuke wale nō, kahi e hoʻomaikaʻi maikaʻi ai i ka hana lapaʻau. ʻO nā mea maikaʻi o ka huahana i hōʻuluʻulu ʻia ma lalo nei:

• ʻO ka maʻalahi o ka hana: ʻaʻohe pono no ka paʻakikī ma mua o ka hoʻomaʻamaʻa ʻana, hiki ke hoʻopili pololei ʻia nā laʻana mimi ma ka hāpana, ʻekolu mau ʻanuʻu hana e hoʻopau ai i ka hoʻāʻo, hiki i nā ʻoihana ʻole ke haku ma hope o kahi hoʻomaʻamaʻa pōkole.
• Nā hopena intuitive: ka hoʻohana ʻana i ka ʻōnaehana hoʻomohala kala, hiki ke heluhelu mua ʻia ka maka ʻōlohelohe, hiki i nā kāleka kala like ke semi-quantitative analysis, e hoʻokō i nā pono o nā hiʻohiʻona noiʻi like ʻole.
• Maikaʻi a maikaʻi hoʻi: ʻoi aku ka haʻahaʻa o ke kumukūʻai o ka hoʻāʻo hoʻokahi ma mua o nā hoʻokolohua hoʻokolohua, kūpono ia no ka nānā ʻana i ka nui a me ka nānā ʻana i ka wā lōʻihi, a he waiwai koʻikoʻi koʻikoʻi.

• ʻO ka waiwai hoʻolaha mua: hiki ke ʻike ʻia ka pōʻino o ka puʻupaʻa ma mua o 3-5 mau makahiki ma mua o nā hōʻailona hana kuʻuna renal, e lanakila ana i ka manawa kūpono no ka hana lapaʻau.

Nā hiʻohiʻona noiʻi lapaʻau a me nā ʻōlelo kuhikuhi

Ka pololeiALB Urine Testloaʻa i kahi ākea o nā hiʻohiʻona noi. Ma ke kahua o ka maʻi maʻi mellitus, ʻo nā alakaʻi alakaʻi o ka American Diabetes Association (ADA) e kuhikuhi pono i nā mea maʻi āpau me ka maʻi diabetes type 1 ≥ 5 mau makahiki a me nā mea maʻi āpau me ka maʻi diabetes type 2 pono e hoʻāʻo i ka urine albumin i kēlā me kēia makahiki. I ka hoʻokele hypertension, ua helu nā alakaʻi alakaʻi hypertension ESC/ESH i ka microalbuminuria ma ke ʻano he hōʻailona koʻikoʻi o ka pōʻino o ke kino. Eia hou, ua kūpono ka reagent no nā hiʻohiʻona he nui e like me ka loiloi maʻi cardiovascular, ka nānā ʻana i ka hana renal i ka poʻe ʻelemakule, a me ka nānā ʻana i ka renal i ka wā hāpai.

ʻO ka hoihoi nui, ʻo kēia huahana i kūpono i nā pono o ka maʻi hierarchical a me ka mālama ʻana. Hiki ke hoʻohana ʻia ma ke ʻano he mea hana hoʻomaʻamaʻa maikaʻi no ka maʻi maʻi maʻi ma nā keʻena olakino mua e like me nā halemai kaiaulu a me nā keʻena olakino o ke kaona; ma nā keʻena nephrology a me endocrinology o nā haukapila ākea, hiki ke hoʻohana ʻia ma ke ʻano he mea hana koʻikoʻi no ka mālama ʻana i ka maʻi a me ka nānā ʻana i ka pono; ma nā keʻena hoʻomaʻamaʻa olakino, hiki ke hoʻohui ʻia i loko o nā pūʻolo hoʻomaʻamaʻa olakino e hoʻonui i ka helu o ka ʻike ʻana i ka hōʻeha ʻana o ka puʻupaʻa mua; a ua manaʻo ʻia e komo i ka mākeke mālama olakino ʻohana ma hope o ka hōʻoia hou ʻana i ka wā e hiki mai ana.

Ka hopena

Ke nānā mau nei mākou ʻo Baysen Medical i ka ʻenehana diagnostic e hoʻomaikaʻi i ka maikaʻi o ke ola. Ua hoʻomohala mākou i 5 mau ʻenehana ʻenehana- Latex, colloidal gula, Fluorescence Immunochromatographic Assay, Molecular, Chemiluminescence Immunoassay.We haveHoao ALB FIA no ka nānā ʻana i ka hōʻeha ʻāʻī o ka wā mua