C-peptide, a i ʻole ka peptide linking, he waikawa amino kaulahao pōkole e pāʻani ana i kahi kuleana koʻikoʻi i ka hana ʻana o ka insulin i loko o ke kino. He huahana ia o ka hana ʻana o ka insulin a hoʻokuʻu ʻia e ka pancreas ma nā nui like me ka insulin. ʻO ka hoʻomaopopo ʻana i ka C-peptide hiki ke hāʻawi i nā ʻike waiwai nui i nā kūlana olakino like ʻole, ʻoi aku ka maʻi diabetes.

Ke hana ka pancreas i ka insulin, hana mua ia i kahi molekole nui aʻe i kapa ʻia ʻo proinsulin. A laila māhele ʻia ka Proinsulin i ʻelua ʻāpana: insulin a me C-peptide. ʻOiai ke kōkua nei ka insulin i ka hoʻoponopono ʻana i nā pae kō koko ma ka hoʻolaha ʻana i ka lawe ʻana o ka glucose i loko o nā cell, ʻaʻohe kuleana pololei o C-peptide i ka metabolism glucose. Eia nō naʻe, he hōʻailona koʻikoʻi ia no ka loiloi ʻana i ka hana pancreatic.

ʻO kekahi o nā hoʻohana nui no ke ana ʻana i nā pae C-peptide ʻo ia ka ʻike a me ka mālama ʻana i ka maʻi diabetes. I ka poʻe me ka maʻi diabetes type 1, hoʻouka ka ʻōnaehana pale a luku i nā cell beta e hana ana i ka insulin i loko o ka pancreas, e hopena ana i nā pae haʻahaʻa a ʻike ʻole ʻia paha o ka insulin a me C-peptide. I ka hoʻohālikelike ʻana, ʻo ka poʻe me ka maʻi diabetes type 2 he mau pae C-peptide maʻamau a kiʻekiʻe paha no ka mea hana ko lākou kino i ka insulin akā kūʻē i kona hopena.

Hiki i nā ana ʻana o C-peptide ke kōkua i ka hoʻokaʻawale ʻana ma waena o ka maʻi diabetes type 1 a me type 2, alakaʻi i nā hoʻoholo lapaʻau, a nānā i ka pono o ka lāʻau. No ka laʻana, hiki i kahi mea maʻi me ka maʻi diabetes type 1 i hana ʻia i kahi hoʻoili cell islet ke nānā ʻia ko lākou mau pae C-peptide e loiloi i ka holomua o ke kaʻina hana.

Ma waho aʻe o ka maʻi diabetes, ua aʻo ʻia ʻo C-peptide no kona hopena palekana i nā ʻano ʻiʻo like ʻole. Manaʻo kekahi mau noiʻi he mau waiwai anti-inflammatory ko C-peptide e hiki ke kōkua i ka hōʻemi ʻana i nā pilikia e pili ana i ka maʻi diabetes, e like me ka hōʻino ʻana o ke aʻalolo a me nā puʻupaʻa.

I ka hopena, ʻoiai ʻaʻole pili pololei ka C-peptide i nā pae glucose koko, he biomarker waiwai nui ia no ka hoʻomaopopo ʻana a me ka mālama ʻana i ka maʻi diabetes. Ma ke ana ʻana i nā pae C-peptide, hiki i nā mea lawelawe olakino ke loaʻa ka ʻike i ka hana pancreatic, hoʻokaʻawale ma waena o nā ʻano maʻi diabetes, a hoʻopilikino i nā hoʻolālā lapaʻau i nā pono pilikino.

Loaʻa iā mākou ʻo Baysen MedicalPahu hoʻāʻo C-peptide ,Pahu hoʻāʻo insulina mePahu hoʻāʻo HbA1Cno ka maʻi diabetes