ʻO C-peptide, i ʻike ʻia hoʻi ʻo linking peptide, he waikawa amino koʻikoʻi ia i ka hana ʻana o ka insulin. Hoʻokuʻu ʻia e ka pancreas me ka insulin a lawelawe ma ke ʻano he māka koʻikoʻi no ka loiloi ʻana i ka hana pancreatic. ʻOiai ʻo ka insulin e hoʻoponopono i nā pae kō koko, he ʻokoʻa ke kuleana o C-peptide a he mea nui ia i ka hoʻomaopopo ʻana i nā kūlana olakino like ʻole, ʻoiai ka maʻi diabetes. Ma ke ana ʻana i nā pae C-peptide, hiki i nā mea lawelawe olakino ke hoʻokaʻawale ma waena o ke ʻano 1 a me ke ʻano 2 diabetes, alakaʻi i nā hoʻoholo lapaʻau, a nānā i ka pono o ka lāʻau lapaʻau.

He mea nui ke ana ʻana i nā pae C-peptide i ka ʻike ʻana a me ka mālama ʻana i ka maʻi diabetes. ʻO ka poʻe me ka maʻi diabetes type 1 he haʻahaʻa a ʻike ʻole ʻia paha nā pae o ka insulin a me ka C-peptide ma muli o ka hoʻouka ʻana o ka ʻōnaehana pale i nā cell beta e hana ana i ka insulin. Ma ka ʻaoʻao ʻē aʻe, ʻo ka poʻe me ka maʻi diabetes type 2 he mau pae C-peptide maʻamau a kiʻekiʻe paha no ka mea hana ko lākou kino i ka insulin akā kūʻē i kona hopena. ʻO ka nānā ʻana i nā pae C-peptide i nā maʻi, e like me ka poʻe e hana ʻia ana i nā hoʻoili cell islet, hiki ke hāʻawi i nā ʻike waiwai i ka holomua o nā kaʻina hana lapaʻau.

Ua noiʻi pū nā haʻawina i nā hopena palekana o C-peptide ma nā ʻiʻo like ʻole. Hōʻike kekahi mau noiʻi he mau waiwai anti-inflammatory paha ko C-peptide e hiki ke kōkua i ka hōʻemi ʻana i nā pilikia e pili ana i ka maʻi diabetes, e like me ka hōʻino ʻana o ke aʻalolo a me nā puʻupaʻa. ʻOiai ʻaʻole pili pololei ʻo C-peptide i nā pae glucose koko, lawelawe ia ma ke ʻano he biomarker waiwai nui no ka hoʻokele ʻana i ka maʻi diabetes a me ka hoʻopilikino ʻana i nā hoʻolālā lapaʻau i nā pono pilikino. Inā makemake ʻoe e ʻeli hohonu i ka hoʻomaopopo ʻana i ka maʻi diabetes, e mālama ana menūhou ʻoihanae pili ana i ka mālama ola kino a me nā holomua lapaʻau hiki ke hāʻawi i nā ʻike waiwai no nā poʻe loea a me nā mea maʻi.