Interleukin-6 bụ polypeptide nke nwere agbụ glycoprotein abụọ, nke nwere ibu molekul nke 130kd. Dịka onye otu dị mkpa na netwọk cytokine, interleukin-6 (IL-6) na-arụ ọrụ dị mkpa na mmeghachi omume mkpali dị oke njọ, ọ nwekwara ike ime ka mmeghachi omume imeju dị ngwa ngwa, ma kpalite mmepụta nke protein C-reactive (CRP) na fibrinogen. Ọtụtụ ọrịa na-efe efe nwere ike ibute mmụba na ọkwa IL-6 serum, ọkwa IL-6 na-ejikọkwa ya na nsonaazụ ndị ọrịa. Dịka cytokine pleiotropic nwere ọrụ dị ukwuu, IL-6 na-apụta site na mkpụrụ ndụ T, mkpụrụ ndụ B, mononuclear phagocyte, na mkpụrụ ndụ endothelial, ọ bụkwa akụkụ dị mkpa nke netwọk mgbasa ozi mkpali. Mgbe mmeghachi omume mkpali mere, IL-6 na-ebu ụzọ mepụta, nke na-akpali mmepụta nke CRP na procalcitonin (PCT) mgbe emepụtara ya. A ga-emepụta ya ngwa ngwa ma ọ bụrụ na ọrịa ebute, mmerụ ahụ dị n'ime na mpụga, ịwa ahụ, mmeghachi omume nrụgide, ọnwụ ụbụrụ, tumorigenesis, na usoro mmeghachi omume mbufụt dị oke njọ nke ọnọdụ ndị ọzọ. IL-6 na-etinye aka na mmepe na mmepe nke ọtụtụ ọrịa, ọkwa ọbara ya na-ejikọta ya na mbufụt, nje virus na ọrịa autoimmune, mgbanwe ya na-emekwa tupu CRP. Dịka nsonaazụ nyocha si kwuo, ọkwa IL-6 na-abawanye ngwa ngwa mgbe nje bacteria butere ọrịa, ọkwa PCT na-abawanye mgbe awa 2 gachara, ebe CRP na-abawanye ngwa ngwa mgbe awa 6 gachara. Nsịpụta na-adịghị mma ma ọ bụ ngosipụta mkpụrụ ndụ ihe nketa nke IL-6 nwere ike ibute ọtụtụ ọrịa, enwere ike ịtinye nnukwu IL-6 n'ime ọbara na ọnọdụ ọrịa, nchọpụta nke IL-6 dịkwa oke mkpa na nchọpụta ọrịa na mkpebi amụma.