Chikungunya Virus (CHIKV) Overview

Chikungunya virus (CHIKV) ndi matenda oyambitsidwa ndi udzudzu omwe amayambitsa Chikungunya fever. Nawa chidule chatsatanetsatane cha kachilomboka:

1. Makhalidwe a Virus

• Gulu: Ndi laTogaviridaefamily, genusAlphavirus.
• Genome: Kachilombo kakang'ono ka RNA kachingwe.
• Njira zopatsirana: Zofalitsidwa makamaka ndi Aedes aegypti ndi Aedes albopictus, ma vectors omwewo monga ma virus a dengue ndi Zika.

• Madera omwe ali pachiwopsezo: Madera otentha komanso otentha ku Africa, Asia, America, ndi zilumba za Indian Ocean.

2. Kuchita bwino kwachipatala

• Nthawi yoyamwitsa: Nthawi zambiri masiku 3-7.
• Zizindikiro Zodziwika:
  • Kutentha kwakukulu kwadzidzidzi (kupitirira 39 ° C).
  • Kupweteka kwakukulu kwamagulu (makamaka kumakhudza manja, manja, mawondo, ndi zina zotero), zomwe zimatha kwa masabata mpaka miyezi.
  • Maculopapular totupa (nthawi zambiri pa thunthu ndi miyendo).
  • Kupweteka kwa minofu, mutu, nseru tec.
• Zizindikiro zosatha: Pafupifupi 30% -40% ya odwala amamva kupweteka kwapakhosi kosalekeza, komwe kumatha kwa miyezi kapena zaka.
• Kuopsa kwa matenda aakulu: Ana obadwa kumene, okalamba ndi odwala omwe ali ndi matenda aakulu amatha kukhala ndi vuto la ubongo (monga meningitis) kapena imfa, koma chiwerengero cha imfa ndi chochepa (<1%).

3. Matenda ndi chithandizo

• Njira zowunikira:
  • Kuyesa kwa serological: ma antibodies a IgM/IgG (amawoneka pafupifupi masiku 5 atayamba).
  • Mayeso a molekyulu: RT-PCR (kuzindikira ma virus a RNA mu gawo lalikulu).
  • Kufunika kusiyanitsadengue malungo, Zika virus, etc. (zizindikiro zofanana)
• Chithandizo:
  • Palibe mankhwala enieni oletsa tizilombo toyambitsa matenda, ndipo chithandizo chazizindikiro ndicho chithandizo chachikulu:
    • Kuchepetsa ululu / malungo (peŵani aspirin chifukwa cha chiopsezo chotaya magazi).
    • Hydration ndi kupuma.
    • Kupweteka m'malo olumikizirana mafupa kungafune mankhwala oletsa kutupa kapena physiotherapy.

4. Njira zodzitetezera

• Kuletsa udzudzu:
  • Gwiritsani ntchito maukonde a udzudzu ndi mankhwala oletsa udzudzu (kuphatikiza DEET, picaridin, etc.).
  • Chotsani madzi osasunthika (chepetsani malo oswana udzudzu).
• Upangiri wapaulendo: Samalani popita kumadera omwe ali ndi kachilomboka komanso kuvala zovala za manja aatali.
• Kupanga katemera: Pofika mchaka cha 2023, palibe katemera wamalonda womwe wakhazikitsidwa, koma katemera wina wa katemera ali m'mayesero achipatala (monga katemera wa tizilombo toyambitsa matenda).

5. Kufunika kwaumoyo wa anthu

• Kuopsa kwa Mliri: Chifukwa cha kufalikira kwa udzudzu wa Aedes komanso kutentha kwanyengo, kuchuluka kwa kufalitsa kungathe kukulirakulira.
• Mliri wapadziko lonse: M’zaka zaposachedwapa, miliri yabuka m’madera ambiri ku Caribbean, South Asia (monga India ndi Pakistan) ndi Africa.

6. Kusiyana kwakukulu ndiDengueMalungo

• Zofanana: Onsewa amafalitsidwa ndi udzudzu wa Aedes ndipo amakhala ndi zizindikiro zofanana (kutentha thupi, zotupa).
• Kusiyanitsa: Chikungunya amadziwika ndi ululu wopweteka kwambiri, pamenedenguenthawi zambiri zimayambitsa kukhetsa magazi kapena kunjenjemera.

Pomaliza:

We Baysen Medical nthawi zonse timayang'ana kwambiri njira zodziwira matenda kuti tikhale ndi moyo wabwino. Tapanga nsanja 5 zaukadaulo- Latex, golide wa colloidal, Fluorescence Immunochromatographic Assay, Molecular,Chemiluminescence Immunoassay.Timayang'ananso pakuyesa matenda opatsirana,Tili ndiDengue NSI mayeso ofulumira,Mayeso a Dengue IgG/IgM mwachangu, Dengue NSI ndi IgG/IgM zimaphatikiza mayeso ofulumira