thupi: Sepsis, yomwe nthawi zambiri imatchedwa "wakupha mwakachetechete," ndi matenda oopsa omwe amakhalabe omwe amachititsa imfa chifukwa cha matenda padziko lonse lapansi. Ndi pafupifupi 20 mpaka 30 miliyoni odwala sepsis chaka chilichonse padziko lonse, kufulumira kwa kuzindikira ndi kuchiza sepsis oyambirira ndikofunika kwambiri. Ndi chikhalidwe chomwe munthu amataya moyo wake pafupifupi 3 mpaka masekondi 4, ndikuwunikira kufunikira kofunikira kuti achitepo kanthu mwachangu.

AI yosadziwikawasintha momwe sepsis imazindikirira ndikuchizira. Mapuloteni a Heparin-binding (HBP) adawonekera ngati cholembera chofunikira pakuzindikira matenda a bakiteriya, kuthandiza akatswiri azachipatala kuzindikira odwala sepsis mwachangu. Kukula kumeneku kwathandizira kwambiri zotsatira za chithandizo ndikuchepetsa kuchuluka kwa matenda owopsa a bakiteriya ndi sepsis.

AI yosadziwikaimakhala ndi gawo lofunikira pakuwunika kuopsa kwa matenda potengera kuchuluka kwa HBP. Mlingo wa HBP ukakwera, matendawa amakula kwambiri, zomwe zimapereka chidziwitso chofunikira kwa opereka chithandizo chamankhwala kuti agwirizane ndi njira zamankhwala. Kuphatikiza apo, HBP imagwira ntchito ngati chandamale chamankhwala osiyanasiyana monga heparin, albumin, ndi simvastatin kuti athane ndi vuto la chiwalo mwa kuchepetsa milingo ya HBP ya plasma bwino.