Kupambana Kwamayeso Kosasokoneza:Fecal Calprotectin"Kudutsa malire" Kuthandizira Kuzindikira Koyambirira kwa Kutupa kwa Upper GI mwa Ana

Pankhani yofufuza matenda a m'mimba mwa ana, endoscopy yakhala "yezo" yodziwika bwino yodziwira kutupa kwa m'mimba. Komabe, kufufuza kosautsa kumeneku sikumangotsatizana ndi kusapeza bwino kwa thupi kwa ana, makamaka achichepere, komanso nthawi zambiri kumabweretsa mantha aakulu m’maganizo ndi kuvutika kugwirizana. Izi zimapangitsa makolo ambiri kukayikira panthawi ya matenda oyambirira ndipo akhoza kuphonya mwayi wochitapo kanthu mwamsanga.Posachedwapa, kafukufuku watsopano wachipatala ndi machitidwe ogwiritsira ntchito abweretsa nkhani zosangalatsa:fecal calprotectin (FCP), chizindikiro chokhwima chosasunthika chowunikira matenda a m'munsi mwa m'mimba, chikuwonetsa kuthekera kwakukulu pakuzindikira koyambirira kwa kutupa kwapamwamba kwa m'mimba mwa ana, kukwaniritsa "crossover" yodabwitsa kuchokera ku "matumbo apansi" kupita ku "matumbo apamwamba".

Kuchokera pa Vuto la "Gold Standard" mpaka Kumayambiriro kwa Mayeso Osasokoneza

Kutupa kwapamwamba kwa m'mimba monga gastritis ndi gastroduodenitis sikwachilendo kwa ana, ndipo zomwe zimayambitsa zimaphatikizapo matenda, mankhwala osokoneza bongo, ndi kupsinjika maganizo. Mwachizoloŵezi, matenda amafunika kuyang'anitsitsa ndi kuwunika kwa minofu kudzera mu gastroscopy, yomwe ndi njira yovuta komanso yovuta. Njira zodziwira zosagwiritsidwa ntchito komanso zosavuta nthawi zonse zakhala kuyembekezera kwa madokotala ndi mabanja a ana omwe ali ndi matendawa.Fecal calprotectinndi mapuloteni omwe amawonetsa kuphatikizika kwa neutrophil. Pamene m'mimba mucosa chotupa, ndende yake idzawonjezeka kwambiri. Kwa zaka zambiri, wakhala akugwiritsidwa ntchito kwambiri poyesa zochitika za matenda opweteka a m'mimba (IBD) komanso kusiyana kwa matenda opweteka a m'mimba (IBS), makamaka chifukwa cha kutupa kwamatumbo.

Kafukufuku wa sayansi amatsimikizira maziko olimba a ntchito "zodutsa malire".

Kafukufuku wochulukirapo akuwonetsa kuti cholembera chotupachi sichimangokhala m'matumbo. Pamene kutupa kwakukulu kumachitika m'mimba ya m'mimba (monga m'mimba ndi duodenum), maselo otupa amalowanso ndikumasula.calprotectin. Puloteniyi imayenda m'matumbo a m'mimba pamodzi ndi madzi am'mimba ndi zotsalira za chakudya, ndipo pamapeto pake zimadziwika mu chopondapo. Kafukufuku waposachedwapa wa ana asonyeza zimenezofecal calprotectinmilingo imakhala yokwera kwambiri kwa ana omwe ali ndi matenda a endoscopically gastritis kapena duodenitis poyerekeza ndi omwe ali ndi dyspepsia yogwira ntchito kapena zofukufuku zachibadwa za endoscopic. Izi zikuwonetsa kuti kuyezetsa kwa FC kungagwiritsidwe ntchito ngati chida chowunikira chothandizira madokotala poyambira kuzindikira ana omwe ali pachiwopsezo chachikulu cha kutupa kwamatumbo am'mimba pakati pa ana ambiri omwe ali ndi zizindikiro monga kupweteka m'mimba, kutupa, ndi nseru.

Phindu Lachipatala: Kumanga Njira Yabwino Yowunikira Ana

Kugwiritsa ntchito malire afecal calprotectinwabweretsa maubwino angapo pakuzindikira ndi kuwongolera matenda am'mimba mwa ana:

1.Kutsatira kosasunthika komanso kutsata kwakukulu: Chiyerekezo chaching'ono chokha ndichofunika, ndipo ndondomekoyi imakhala yosasunthika, yomwe imachepetsa kwambiri kulemera kwa thupi ndi maganizo kwa ana. Makolo amavomereza kwambiri njirayi, zomwe zimapangitsa kuti zikhale zosavuta kuti aziyang'anitsitsa mobwerezabwereza m'zipatala zakunja.
2. Chida choyenera choyezera ndi kuwerengera: Kwa ana omwe ali ndi zizindikiro za m'mimba mosalekeza,Fecal Calprotectinkuyezetsa kungathe kuchitidwa poyamba kuti tisiyanitse bwino matenda opweteka ndi ogwira ntchito. NgatiFecal calprotectinmilingo ndi yabwinobwino, zinthu zogwira ntchito zitha kukhala zotsogola kapena chithandizo champhamvu ndikuwonetsetsa kutengera. Ngati milingo ya FC yakwezedwa, imapereka maziko olimba a gastroscopy yowononga, kupewa njira zosafunikira za endoscopic ndikukwaniritsa kugawa kwamankhwala.
3. Kuunikira kothandizira ndi kubwereza: Pambuyo pozindikira kutupa kwapamwamba kwa m'mimba komanso kuyamba kwa chithandizo, kuyang'anira kwamphamvu kwa kusintha kwa thupi.Fecal Calprotectinmilingo imatha kukhala ngati chizindikiritso chowunikira ngati kutupa kwachepa komanso ngati chithandizocho ndi chothandiza. Zingathandizenso kudziwa kuti matenda ayambiranso msanga.

Future Outlook

Zachidziwikire, kugwiritsa ntchito fecal calprotectin m'matumbo am'mimba kumafunikirabe kafukufuku wowonjezera kuti afotokozere bwino mtengo wake wocheperako ndikuchotsa zinthu zina zotsika zam'mimba zomwe zingayambitse kukwezeka kwa FC. Komabe, monga njira yotetezeka, yosavuta, komanso yotsika mtengo yowunikira, mosakayikira imatsegula chitseko chatsopano cha matenda oyambirira a kutupa kwa m'mimba mwa ana. Zimawonetsa kupita patsogolo pakuzindikira matenda am'mimba a ana kupita ku njira yaumunthu komanso yolondola. Timakhulupirira kuti ndi kupitiriza kufufuza mozama komanso zambiri zachipatala,fecal calprotectin,“Nyenyezi yopingasa” imeneyi, idzagwira ntchito yofunika kwambiri poteteza thanzi la ana m’mimba.

Baysen Medical nthawi zonse imayang'ana njira zowunikira kuti mukhale ndi moyo wabwino. Tapanga nsanja 5 zaukadaulo- Latex, golide wa colloidal, Fluorescence Immunochromatographic Assay, Molecular,Chemiluminescence Immunoassay.Tili ndi Golide wa ColloidalFecal calprotectin zida zoyesera ndi Fluorescence ImmunoassayCalprotectin test kitzoyezetsa