Kuyesa Kosalowerera:Kalori yoteteza ku matumbo"Amadutsa Malire" Kuti Athandize Kuzindikira Koyambirira kwa Kutupa kwa M'mimba Mwa Ana

Pankhani yozindikira matenda a m'mimba mwa ana, endoscopy yakhala "muyezo wabwino kwambiri" wodziwira kutupa kwa m'mimba chapamwamba. Komabe, kufufuza kumeneku sikumangobweretsa kusasangalala kwa ana, makamaka aang'ono, komanso nthawi zambiri kumabweretsa mantha akulu amisala komanso zovuta kugwirira ntchito limodzi. Izi zimapangitsa makolo ambiri kukayikira panthawi yodziwira matenda oyamba ndipo angaphonye mwayi wochitapo kanthu msanga. Posachedwapa, kafukufuku watsopano wazachipatala ndi njira zogwiritsira ntchito zabweretsa nkhani zosangalatsa:fecal calprotectin (FCP), chizindikiro chokhwima chosavulaza cha kuwunika matenda am'mimba otsika, chikuwonetsa kuthekera kwakukulu pozindikira msanga kutupa kwa m'mimba chapamwamba mwa ana, zomwe zimapangitsa kuti "kusinthasintha" kodabwitsa kuchokera "m'mimba wapansi" kupita "m'mimba wapamwamba".

Kuchokera pa Vuto la "Gold Standard" mpaka Kuyamba kwa Mayeso Osalowerera

Matenda otupa m'mimba monga gastritis ndi gastroduodenitis si achilendo kwa ana, ndipo zomwe zimayambitsa matendawa ndi matenda, mankhwala osokoneza bongo, ndi kupsinjika maganizo. Mwachikhalidwe, kuzindikira matendawa kumafuna kuyang'aniridwa ndi maso ndi biopsy ya minofu kudzera mu gastroscopy, yomwe ndi njira yovuta komanso yowononga. Njira zosavulaza komanso zosavuta kuzizindikira nthawi zonse zakhala zikuyembekezeredwa ndi madokotala ndi mabanja a ana omwe ali ndi matendawa.Kalori yoteteza ku chimbudzindi puloteni yomwe imasonyeza kusonkhana kwa neutrophil. Pamene mucosa ya m'mimba yatupa, kuchuluka kwake kumawonjezeka kwambiri. Kwa zaka zambiri, yakhala ikugwiritsidwa ntchito kwambiri poyesa ntchito ya matenda otupa m'matumbo (IBD) komanso kuzindikira matenda olakwika a irritable bowel syndrome (IBS), makamaka pochiza kutupa m'matumbo.

Kafukufuku wa sayansi akutsimikizira maziko olimba a ntchito "zodutsa malire"

Kafukufuku wochulukirachulukira akusonyeza kuti chizindikiro chotupachi sichimangokhudza m'matumbo okha. Pamene kutupa kumachitika m'mimba (monga m'mimba ndi duodenum), maselo otupa amalowanso ndikutulutsa.calprotectinPuloteni iyi imayenda m'mimba pamodzi ndi madzi am'mimba ndi zotsalira za chakudya, zomwe pamapeto pake zimapezeka mu ndowe. Kafukufuku waposachedwa mwa ana wasonyeza kuticalprotectin ya m'matumboMlingo wa gastritis kapena duodenitis ndi wokwera kwambiri mwa ana omwe ali ndi vuto la endoscopically confirmed gastritis kapena duodenitis poyerekeza ndi omwe ali ndi dyspepsia yogwira ntchito kapena zotsatira za endoscopic wamba. Ngakhale kuti kuchuluka kwa FC komwe kumachitika chifukwa cha kutupa kwa m'mimba nthawi zambiri kumakhala kotsika kuposa omwe ali ndi IBD yogwira ntchito, kwawonetsa kusiyana kwakukulu poyerekeza ndi anthu athanzi. Izi zikusonyeza kuti mayeso a FC angagwiritsidwe ntchito ngati chida chothandiza chowunikira kuti athandize madokotala kuzindikira ana omwe ali pachiwopsezo chachikulu cha kutupa kwa m'mimba mwa ana ambiri omwe ali ndi zizindikiro monga kupweteka m'mimba, kudzimbidwa, ndi nseru.

Mtengo Wachipatala: Kupanga Njira Yabwino Yodziwira Ana

Kugwiritsa ntchito malire acalprotectin ya m'matumboyabweretsa ubwino wambiri pakupeza ndi kusamalira matenda am'mimba mwa ana:

1. Kusalowa m'malo mwa mankhwala osokoneza bongo komanso kutsatira malamulo ambiri: Kungofunika kutengera ndowe pang'ono chabe, ndipo njirayi siilowa m'malo mwa mankhwala osokoneza bongo, zomwe zimachepetsa kwambiri mavuto akuthupi ndi amisala kwa ana. Makolo akuvomereza kwambiri njirayi, zomwe zimapangitsa kuti zikhale zosavuta kuchita kafukufuku wobwerezabwereza m'zipatala zakunja.
2. Chida chothandiza choyezera ndi kuyeretsa: Kwa ana omwe ali ndi zizindikiro zosalekeza za m'mimba,Kalori yoteteza ku matumboKuyezetsa kungachitike kaye kuti kusiyanitsa bwino pakati pa matenda otupa ndi matenda ogwira ntchito.Kalori yoteteza ku chimbudziMilingo ndi yabwinobwino, zinthu zogwira ntchito zitha kuyikidwa patsogolo kapena chithandizo chochitidwa mwaluso ndipo kuyang'aniridwa kungatengedwe. Ngati kuchuluka kwa FC kwakwezedwa, kumapereka maziko olimba a gastroscopy yolowerera, kupewa njira zosafunikira za endoscopic ndikuwonjezera kugawa kwa zinthu zachipatala.
3. Kuwunika kothandiza kwa momwe matendawa akugwirira ntchito komanso momwe angakhalirenso: Pambuyo pozindikira kutupa kwa m'mimba ndi kuyamba kwa chithandizo, kuyang'anira kusintha kwa matendawaKalori yoteteza ku matumboMlingo wa mankhwalawo ukhoza kukhala chizindikiro chodziwira ngati kutupa kwachepa komanso ngati chithandizocho chili chothandiza. Zingathandizenso kuzindikira kubwereranso kwa matenda msanga.

Chiyembekezo cha Mtsogolo

Zachidziwikire, kugwiritsa ntchito fecal calprotectin m'mimba ya m'mimba kumafunikirabe kafukufuku wowonjezereka kuti afotokoze bwino momwe imagwirira ntchito bwino ndikuchotsa zinthu zina zotsika m'mimba zomwe zingayambitse kuchuluka kwa FC. Komabe, monga njira yotetezeka, yosavuta, komanso yotsika mtengo yoyezera, mosakayikira imatsegula khomo latsopano lodziwira msanga kutupa kwa m'mimba ya m'mimba mwa ana. Ikuwonetsa kupita patsogolo pakuzindikira matenda am'mimba a ana kupita ku njira yachifundo komanso yolondola. Tikukhulupirira kuti ndi kafukufuku wopitilira komanso chidziwitso chachipatala chosonkhanitsidwa,calprotectin ya m'matumbo,"nyenyezi yosakanikirana" iyi, idzachita gawo lofunika kwambiri poteteza thanzi la m'mimba mwa ana.

Baysen Medical nthawi zonse imayang'ana kwambiri njira zodziwira matenda kuti ipititse patsogolo moyo wabwino. Tapanga njira zisanu zaukadaulo - Latex, colloidal gold, Fluorescence Immunochromatographic Assay, Molecular, Chemiluminescence Immunoassay. Tili ndi Colloidal Gold.Kalori yoteteza ku chimbudzi zida zoyesera ndi Fluorescence ImmunoassayZida zoyesera za Calprotectinkuti ayesedwe