H. pyloriBungwe la WHO limaika m'gulu la matenda a khansa m'gulu loyamba ndipo ndi chinthu chachikulu chomwe chimayambitsa matenda a gastritis osatha, zilonda zam'mimba, komanso khansa ya m'mimba. Popeza kuchuluka kwa matenda m'madera ambiri kuli kwakukulu, kuyezetsa koyambirira ndi kuzindikira matenda molondola ndikofunikira kwambiri popewa ndikuwongolera matenda am'mimba. Monga kampani yodziwitsa zachipatala, timapereka njira yodziwira matenda nthawi imodzi—kuyambira kuyezetsa koyambirira mpaka kuyezetsa kolondola—kuti tikwaniritse zosowa zosiyanasiyana zachipatala komanso kuyezetsa.

Kuwunika Moyenera: Chowunikira mpweya wa urea wa C13 ndi C14ndi zida zoyesera

Pa kuyezetsa thanzi lalikulu komanso kuyezetsa odwala osapita kuchipatala,Mpweya wa C13/C14 Urea Mayesowa amadziwika padziko lonse lapansi ngati muyezo wagolide wopezera H. pylori, ndipo amapereka mayeso osalowa m'thupi molondola kuposa 95%. C13 isotope siigwiritsa ntchito ma radiation ndipo ndi yoyenera anthu onse, kuphatikizapo amayi apakati ndi ana, pomwetmayeso a C14imapereka njira ina yotsika mtengo komanso yothandiza.

Mofananamo, timapereka njira yabwinoHP-AB (antibody) ndiHP-AG (antigen) zida zoyesera mwachangu. Mayeso a HP-AB amazindikira ma antibodies pogwiritsa ntchito magazi kapena seramu ya chala, zomwe zimabweretsa zotsatira mkati mwa mphindi 15—zabwino kwambiri pa kafukufuku wa matenda. Mayeso a HP-AG amazindikira ma antigen m'zitsanzo za ndowe, zomwe zimasonyeza mwachindunji momwe matenda alili. Amathandiza ngati chowonjezera chothandiza pa mayeso a mpweya, makamaka kwa anthu apadera komwe kuyesa kwina kungakhale kovuta.

Kuyeza Kolondola: Ukadaulo wa Kuyeza kwa Mphamvu ya Mthupi

Kuti tikwaniritse zosowa zachipatala zowunikira matenda ndi kuwunika momwe mankhwala amathandizira, tayambitsa kuchuluka kwaHP-AGndiMa reagent a HP-ABmothandizidwa ndiWIZ-101ndiWIZ-A203mapulatifomu. Dongosololi limagwiritsa ntchito nthawi yokhazikika yowunikira ma immunochromatography, kuphatikiza ma antibodies enaake ndi ma microspheres a fluorescent. Mosiyana ndi mizere yoyesera yachikhalidwe, ukadaulo uwu umathandizira kuyeza molondola kuchuluka kwa ma antibodies/antigen. Izi sizimangothandiza madokotala kuwunika kuopsa kwa matenda komanso zimathandiza kuwunika molondola zotsatira za chithandizo chothetsera matenda, kupereka deta yodalirika kwambiri popanga zisankho zachipatala.

Kuyambira kuyesa mpweya pogwiritsa ntchito mass spectrometry mpaka immunochromatography, komanso kuyambira pakuwunika kwa qualitative mpaka pa fluorescence-based quantity, tadzipereka kupereka zinthu zambiri zomwe zimathandiza mabungwe azaumoyo kuti azitha kupewa ndi kuwongolera matenda am'mimba moyenera.H. pylorimatenda opatsirana.