Polimbana ndi kukana maantibayotiki ndi sepsis, chizindikiro chimodzi chokha chikusintha malamulo a mankhwala odzidzimutsa: Procalcitonin (PCT). Kale, kuyezetsa PCT kunali kofunikira kwambiri m'ma laboratories, tsopano kwakhala chida chotsogola kwa asing'anga padziko lonse lapansi.

Kuchuluka kwa PCT kumawonjezeka kwambiri chifukwa cha matenda a bakiteriya koma kumakhalabe kotsika panthawi ya matenda a mavairasi kapena kutupa. Kusiyana kumeneku n'kofunika kwambiri. Chaka chilichonse, odwala mamiliyoni ambiri amalandira maantibayotiki osafunikira a bronchitis kapena fuluwenza, zomwe zimapangitsa kuti vuto la tizilombo toyambitsa matenda tosamva mankhwala lichepe. "Mwa kuyeza PCT, tikhoza kuyimitsa maantibayotiki molimba mtima pamene kuchuluka kwake kuli kotsika," akutero Dr. Emily Hart, katswiri wa matenda opatsirana. "Izi zimasunga zida zathu zodzitetezera ku mabakiteriya enieni."

Kupatula kuyang'anira thanzi, PCT imapulumutsa moyo wa sepsis. Zizindikiro zachikhalidwe zimatha kukhala zosamveka bwino, koma kuchuluka kwa PCT kumatsimikizira kuti mabakiteriya akuukira m'magazi maola angapo zotsatira za kuyeza magazi zisanakonzedwe. Pa ola lililonse chithandizo chimachedwa, imfa zimawonjezeka ndi 8%. Kuyezetsa PCT mwachangu kumalola madokotala kusiyanitsa sepsis ndi kutupa kosapatsirana m'thupi nthawi yomweyo, zomwe zimayambitsa chisamaliro champhamvu kwa iwo omwe akufunikira - ndikupewa kulandira chithandizo chamankhwala kwa iwo omwe sakuchifuna.

Zipatala zomwe zikugwiritsa ntchito njira za PCT zanena kuti masiku opha tizilombo toyambitsa matenda achepa ndi 40% ndipo anthu ambiri akukhala ku ICU kwa nthawi yochepa kwambiri. Pamene mavairasi opumira m'nyengo yozizira akuchulukirachulukira, mayesowa amaletsa kulakwitsa komwe kumachitika pochiza zizindikiro za mavairasi ndi mankhwala a bakiteriya.

Procalcitonin si nambala yokha; ndi njira yodziwira mankhwala olondola. Mu nthawi yomwe maantibayotiki onse amawerengedwa ndipo mphindi iliyonse ya sepsis ndi yofunika, kuyezetsa PCT sikulinso chinthu chapadera—ndi muyezo wa chisamaliro.