Intangiriro: Akamaro k'ubuvuzi ko gukurikirana imikorere y'impyiko hakiri kare:

Indwara z'impyiko zidakira (CKD) zabaye ikibazo gikomeye ku buzima rusange ku isi. Dukurikije imibare y'Ishami ry'Umuryango w'Abibumbye ryita ku Buzima, abantu bagera kuri miliyoni 850 ku isi barwaye indwara zitandukanye z'impyiko, kandi umubare w'indwara z'impyiko zidakira ku isi ugera kuri 9.1%. Igikomeye kurushaho ni uko indwara z'impyiko zidakira zigaragara, bigatuma umubare munini w'abarwayi babura umwanya mwiza wo kwitabwaho. Muri urwo rwego,mikoroalbuminuria, nk'ikimenyetso cy'impyiko cyangiritse hakiri kare, byarushijeho kuba ingirakamaro. Uburyo gakondo bwo gupima imikorere y'impyiko nka serum creatinine n'igipimo cy'isesengura rya glomerular filtration rate (eGFR) bizagaragaza gusa ibitagenda neza iyo imikorere y'impyiko yatakaye ku kigero kirenga 50%, mu gihe gupima albumin y'inkari bishobora gutanga ibimenyetso by'uburinzi hakiri kare iyo imikorere y'impyiko yatakaye ku kigero cya 10-15%.

Agaciro k'ubuvuzi n'uko ibintu bimeze ubuALBikizamini cy'inkari

Albumin (ALB) ni poroteyine nyinshi cyane mu nkari ku bantu bazima, aho igipimo gisanzwe cyo gusohora albumin mu nkari kiri hagati ya 30-300mg/24h, bisobanurwa ko ari microalbuminuria, kandi iki cyiciro ni igihe cy'indashyikirwa cyo gutabara mu kugabanya kwangirika kw'impyiko. Kuri ubu, uburyo bukunze gukoreshwa cyaneALBUburyo bwo kuvumbura indwara mu buvuzi burimo isuzuma rya radioimmunoassay, isuzuma rya enzyme-linked immunosorbent assay (ELISA), immunoturbidimetry, nibindi, ariko ubu buryo muri rusange bufite ibibazo nko gukora ibintu bigoye, gukoresha igihe kirekire, cyangwa gukenera ibikoresho byihariye. Cyane cyane ku bigo by’ubuvuzi by’ibanze no mu bihe byo kugenzura mu ngo, ikoranabuhanga rihari riragoye guhaza ibyifuzo byo koroshya, kwihuta, no gukora neza, bigatuma umubare munini w’abarwayi bafite ikibazo cy’impyiko hakiri kare bataboneka ku gihe.

Iterambere Rishya mu By'ubuhangaIkizamini cy'inkari za ALBReagent

Mu rwego rwo guhangana n'imbogamizi z'ikoranabuhanga risanzwe rikoreshwa mu gupima, isosiyete yacu yateguye PrecisionIkizamini cy'inkari za ALB Reagent kugira ngo igere ku iterambere ry’ikoranabuhanga. Reagent ikoresha ikoranabuhanga rigezweho rya immunochromatographic rifite affinity yo hejuru kandi rifite umwihariko wo hejuru wa anti-human albumin monoclonal antibody kugira ngo irebe ko ikizamini ari ukuri kandi cyizewe. Udushya mu bya tekiniki tugaragarira ahanini mu bintu bitatu:

• Uburyo bwo kumva bwarushijeho kwiyongera cyane: ubushobozi bwo kumenya neza ingano y’amaraso mu nkari bugera kuri 2mg/L, kandi bushobora kumenya neza ingano y’amaraso mu nkari ya 30mg/amasaha 24, ibyo bikaba ari byiza cyane kurusha uburyo bwo kumva ibyuma bisanzwe bipima.
• Ubushobozi bwo kurwanya ingaruka mbi: Binyuze mu miterere yihariye ya sisitemu y’ubuhumekero, ishobora gutsinda neza ingaruka mbi z’ihindagurika rya pH y’inkari, impinduka mu mbaraga za iyoni n’ibindi bintu ku bisubizo by’ibizamini, bigatuma ikizamini kiguma neza mu bihe bitandukanye by’umubiri.
• Gupima mu buryo bushya: umusomyi wihariye umufasha ashobora kubona uburyo bwo gupima mu buryo buciriritse kuva ku buryo bungana kugeza ku buryo bungana, uburyo bwo gupima bungana na 0-200mg/L, kugira ngo ahuze n'ibikenewe mu buvuzi bitandukanye kuva ku gusuzuma kugeza ku gukurikirana.

Imikorere n'Ibyiza by'Umusaruro

Iyi reagent yemewe mu bitaro byinshi by’icyiciro cya gatatu, igaragaza ibimenyetso by’imikorere myiza cyane. Ugereranyije n’ikigereranyo cya zahabu cyo gupima albumin y’inkari mu masaha 24, igipimo cy’isano kigera kuri 0.98; igipimo cy’impinduka hagati y’inkari n’impinduka hagati y’inkari kiri munsi ya 5%, kiri munsi cyane y’igipimo cy’inganda; igihe cyo kuyimenya ni iminota 15 gusa, ibyo bikaba byongera cyane imikorere myiza y’akazi k’ubuvuzi. Ibyiza by’umuti biravugwa muri make hano hepfo:

• Koroshya igikorwa cyo kubaga: nta mpamvu yo kuvura inkari mu buryo bugoye, ingero z'inkari zishobora kubarwa ku rugero, kubagwa mu byiciro bitatu kugira ngo ikizamini kirangire, abatari abanyamwuga bashobora kubikora neza nyuma y'amahugurwa magufi.
• Ibisubizo by'amarangamutima: gukoresha sisitemu yo guteza imbere amabara asobanutse neza, amaso yambaye ubusa ashobora gusomwa ku ikubitiro, amakarita y'amabara ahuye ashobora kuba isesengura ry'ingano nto, kugira ngo hahuzwe n'ibikenewe mu bihe bitandukanye byo gukoreshwa.
• Birahendutse kandi bifite akamaro: ikiguzi cy'ikizamini kimwe kiri hasi cyane ugereranyije n'ikizamini cyo muri laboratwari, gikwiriye gupimwa ku rwego runini no gukurikiranwa igihe kirekire, kandi gifite akamaro kanini mu bukungu bw'ubuzima.

• Agaciro k'umuburo hakiri kare: kwangirika kw'impyiko gushobora kugaragara imyaka 3-5 mbere y'uko ibimenyetso bisanzwe by'imikorere y'impyiko bitangira, bigatuma habaho igihe cy'ingirakamaro cyo kuvurwa.

Uburyo bwo gukoresha ubuvuzi n'inama ngenderwaho

Uburyo bwo gukora nezaIbipimo by'inkari za ALBtifite uburyo butandukanye bwo kuyikoresha. Mu rwego rwo kuvura diyabete, amabwiriza y’Ishyirahamwe ry’Abanyamerika rya Diabete (ADA) asaba neza ko abarwayi bose barwaye diyabete yo mu bwoko bwa 1 bafite imyaka ≥ 5 n’abarwayi bose ba diyabete yo mu bwoko bwa 2 bagomba gupimwa albumin yo mu nkari buri mwaka. Mu gucunga umuvuduko ukabije w’amaraso, amabwiriza ya ESC/ESH agaragaza microalbuminuria nk'ikimenyetso cy’ingenzi cy’ibyangiritse ku ngingo. Byongeye kandi, reagent ikwiriye mu bihe bitandukanye nko gusuzuma ibyago by’indwara z’umutima n’imitsi, gusuzuma imikorere y’impyiko ku bageze mu za bukuru, no kugenzura impyiko mu gihe batwite.

Igishimishije cyane ni uko iki gicuruzwa gihuye neza n'ibikenewe mu gusuzuma no kuvura indwara z'impyiko mu buryo bw'urwego rw'ubuzima. Gishobora gukoreshwa nk'igikoresho cyiza cyo gupima indwara z'impyiko mu bigo by'ubuvuzi by'ibanze nk'ibitaro by'abaturage n'ibigo nderabuzima byo mu midugudu; mu mashami y'ubuvuzi bw'indwara z'imitsi n'indwara z'imitsi mu bitaro bikuru, gishobora gukoreshwa nk'igikoresho cy'ingenzi mu gucunga indwara no gukurikirana neza imikorere yazo; mu bigo bisuzumisha indwara, gishobora gushyirwa mu mapaki yo gusuzuma ubuzima kugira ngo cyongere igipimo cyo kumenya imvune z'impyiko hakiri kare; ndetse biteganijwe ko kizagera ku isoko ryo gukurikirana ubuzima bw'umuryango nyuma yo kwemezwa mu gihe kizaza.

Umwanzuro

Baysen Medical ihora yibanda ku buryo bwo gusuzuma kugira ngo irusheho kuba nziza. Twakoze ikoranabuhanga rigezweho rigizwe na: Latex, colloidal gold, Fluorescence Immunochromatographic Assay, Molecular, Chemiluminescence Immunoassay. DufiteIkizamini cya ALB FIA yo gukurikirana imvune z'impyiko mu gihe cy'intangiriro