Ferritin: Ikimenyetso cyihuse kandi cy'ukuri cy'isuzuma ry'ubuke bw'icyuma n'amaraso make

Intangiriro

Kubura icyuma gishyushye no kubura amaraso make ni ibibazo by’ubuzima bikunze kugaragara ku isi yose, cyane cyane mu bihugu bikiri mu nzira y’amajyambere, abagore batwite, abana n’abagore bageze mu kigero cyo kubyara. Kubura icyuma gishyushye (IDA) ntibigira ingaruka gusa ku mikorere y’umubiri n’iy’ubwenge bw’abantu, ahubwo bishobora no kongera ibyago byo gutwita no gutinda gukura kw’abana. Kubwibyo, gusuzuma hakiri kare no gufata ingamba ni ingenzi. Mu bimenyetso byinshi byo kumenya, ferritin yabaye igikoresho cy’ingenzi cyo gusuzuma kubura icyuma gishyushye no kubura amaraso make bitewe nuko ifite ubushobozi bwo kumva no kugaragaza umwihariko wayo. Iyi nkuru izavuga ku miterere y’ibinyabuzima bya ferritin, ibyiza byayo mu gusuzuma kubura icyuma gishyushye no kubura amaraso make, ndetse n’akamaro kayo mu buvuzi.

Ibiranga ibinyabuzima byaFerritin

Ferritinni poroteyine ibungabunga icyuma iboneka cyane mu ngingo z'umuntu. Ikorwa ahanini n'umwijima, urwagashya n'umusemburo w'amagufwa. Inshingano yayo y'ingenzi ni ugubika icyuma no kugenzura uburyo icyuma gitunganywa. Mu maraso, ingano yacyoferritinbifitanye isano ryiza n'ubushobozi bw'umubiri bwo kubika icyuma. Bityo, serumferritinUrugero ni kimwe mu bimenyetso by’ingenzi byerekana uko icyuma kibikwa mu mubiri. Mu bihe bisanzwe, urugero rwa ferritin ku bagabo bakuru ruri hagati ya 30-400 ng/mL, naho ku bagore ni hagati ya 15-150 ng/mL, ariko mu gihe cy’ibura ry’icyuma, iki gipimo kizagabanuka cyane.

Ibyiza byaFerritinmu gusuzuma ikibazo cy'ubukene bw'icyuma

1. Gusobanukirwa cyane, kumenya hakiri kare ikibazo cy'ibura ry'ubutare

Iterambere ry'ibura ry'ubutare rigabanyijemo ibice bitatu:

• Icyiciro cyo kubura icyuma: icyuma cyo kubika(ferritin) igabanuka, ariko hemoglobine iba isanzwe;
• Icyiciro cya erythropoiesis yo kubura icyuma:ferritinigabanuka kurushaho, ubwinshi bwa transferrin buragabanuka;
• Icyiciro cyo kubura icyuma: hemoglobin iragabanuka, kandi ibimenyetso bisanzwe byo kubura amaraso bigaragara.

Uburyo busanzwe bwo gupima (nk'ibipimo bya hemoglobine) bushobora gusa kugaragaza ibibazo biri mu cyiciro cyo kubura amaraso, mu giheferritingupima bishobora kugaragaza ibitagenda neza mu gihe cyo kubura icyuma gikozwe mu bwonko mu ntangiriro, bityo bigatanga amahirwe yo kwitabazwa hakiri kare.

2. Gusobanura neza ibintu, bigabanya isuzuma ryibeshye

Indwara nyinshi (nk'ububyimbirwe budakira n'ubwandu) zishobora gutera amaraso make, ariko ntiziterwa no kubura icyuma. Muri iki gihe, kwishingikiriza gusa kuri hemoglobine cyangwa ingano y'umubiri (MCV) bishobora gutuma umuntu atekereza nabi impamvu.Ferritingupima bishobora gutandukanya neza indwara yo kubura icyuma (anemia) n'izindi ndwara zo kubura icyuma (nk'indwara yo kubura icyuma) z'indwara zidakira, bigatuma habaho uburyo bwo gusuzuma indwara neza.

3. Byihuse kandi byoroshye, bikwiriye gukoreshwa mu gusuzuma ibintu binini

Ikoranabuhanga rigezweho ryo gupima ferritin rituma igenwa ry’umuti wihuta kandi uhendutse, kandi rikwiriye imishinga y’ubuzima rusange nko gusuzuma abaturage, kwita ku buzima bw’ababyeyi n’abana, no gukurikirana imirire y’abana. Ugereranyije n’ibizamini byangiza imiterere y’umubiri nk’ibara ry’icyuma mu magufwa (ibipimo ngenderwaho bya zahabu), gupima ferritin mu maraso biroroshye guteza imbere.

Uburyo Ferritin ikoreshwa mu buvuzi mu kuvura indwara zo kubura amaraso

1. Uburyo bwo kuvura inyunganiramirire y'icyuma

Ferritinurugero rushobora gufasha abaganga kumenya niba abarwayi bakeneye inyongeramusaruro ya feri no gukurikirana uburyo ubuvuzi bukora neza. Urugero:

• Ferritin<30 ng/mL: bigaragaza ko ububiko bw'icyuma bwagabanutse kandi ko hakenewe kongerwamo icyuma;
• Ferritin<15 ng/mL: bigaragaza cyane ko umuntu afite ikibazo cyo kubura icyuma gihagije;
• Iyo ubuvuzi bugize akamaro, ferritin urwego ruzagenda ruzamuka buhoro buhoro kandi rushobora gukoreshwa mu gusuzuma imikorere

1. Inyongeramusaruro y'icyuma iyobora

Ferritinurwego rufasha abaganga kumenya ko bakeneye ubuvuzi bw'icyuma no kugenzura imikorere y'ubuvuzi. Urugero:

• Ferritin<30 ng/mL: Bigaragaza ko icyuma cyabuze, gisaba kongerwamo.
• Ferritin<15 ng/mL: Bigaragaza cyane ko umuntu afite ikibazo cyo kubura icyuma.
• Mu gihe cyo kuvurwa, kwiyongeraferritinurwego rwemeza ko ubuvuzi bufite akamaro.

2. Gusuzuma abantu bihariye

• Abagore batwite: ubwinshi bw'ubutare buriyongera mu gihe batwite, kandiferritingupima bishobora gukumira ibibazo by’umubyeyi n’umwana.
• Abana: kubura icyuma gikozwe mu bwonko bigira ingaruka ku iterambere ry’ubwonko, kandi gusuzuma hakiri kare bishobora gutuma habaho ubwiyongere bw’indwara.
• Abarwayi bafite indwara zidakira: nk'abarwayi b'impyiko n'indwara zo mu mara ziterwa n'ububyimba,ferritin hamwe n'ubwinshi bwa transferrin bishobora kugaragaza ubwoko bw'amaraso adahagije.

Imbibi zaFerritinIbizamini n'Ibisubizo

Nubwo ferritin ari cyo kimenyetso gikunzwe cyane mu gusuzuma ikibazo cy’ubuke bw’icyuma, igomba gusobanurwa neza mu bihe bimwe na bimwe:

• Kubyimba cyangwa kwandura indwara:Ferritin, nk'iporoteyine ikora mu gihe cy'ako kanya, ishobora kwiyongera mu buryo butari bwo mu ndwara zandurira mu maraso, mu kibyimba cyangwa mu kubyimba guhoraho. Muri iki gihe, ishobora guhuzwa naPoroteyine ikora C (CRP) ortransferrinubwinshi bw'ibisobanuro kugira ngo habeho umwanzuro wuzuye.
• Indwara y'umwijima:FerritinKu barwayi ba cirrhose, indwara ishobora kwiyongera bitewe n’ibyangiritse by’uturemangingo tw’umwijima, bityo ikaba igomba gusuzumwa hamwe n’ibindi bimenyetso by’imikorere y’icyuma.

Umwanzuro

FerritinGupima byabaye igikoresho cy'ingenzi mu gusuzuma ikibazo cy'ubushyuhe n'amaraso make bitewe n'uburyo bworoshye bwo kumva, kugaragaza imiterere y'umubiri no koroshya indwara. Ntabwo bishobora gusa kumenya ikibazo cy'ubushyuhe hakiri kare no kwirinda ko amaraso make atera, ahubwo binayobora ubuvuzi nyabwo no kunoza imiterere y'umurwayi. Mu buzima rusange no mu buvuzi, guteza imbereferritin Gupima bishobora gufasha kugabanya umutwaro w'indwara zo kubura amaraso mu by'ubutare, cyane cyane ku bantu bafite ibyago byinshi byo kurwara (nk'abagore batwite, abana n'abarwayi b'indwara zidakira). Mu gihe kizaza, hamwe n'iterambere ry'ikoranabuhanga ryo kuvumbura indwara,ferritin bishobora kugira uruhare runini mu gukumira no kugenzura indwara yo kubura amaraso ku isi.

Baysen Medical ihora yibanda ku buryo bwo gusuzuma kugira ngo irusheho kuba nziza. Twakoze ikoranabuhanga rigezweho rigizwe n'ibikoresho bitanu - Latex, colloidal gold, Fluorescence Immunochromatographic Assay, Molecular, Chemiluminescence Immunoassay, OurAgakoresho ko gupima Ferritin byoroshye gukora kandi ushobora kubona igisubizo cy'ikizamini mu minota 15