Troponin T y'umutima (cTnT), igice gito cy'urusobe rwa troponin rugaragara mu buryo bwihariye mu maraso y'umutima, ni kimwe mu bimenyetso by'ingenzi kandi by'ingenzi mu buvuzi bw'indwara z'umutima n'imitsi. Akamaro kayo gashingiye ku buryo idasanzwe bw'umutima, ubushobozi bwayo bwo kumva neza indwara z'umutima, n'uruhare rwayo rw'ingenzi mu gusuzuma, gushyira mu byiciro ibyago byo kurwara indwara z'umutima, no kuvura indwara z'umutima zifata imitsi (ACS) n'izindi ndwara z'umutima.

Mbere na mbere, cTnT ni cyo gipimo cy’ingenzi mu gusuzuma indwara ya myocardial infarction (MI). Mbere yo gukoresha troponin, isuzuma ryashingiraga ku bimenyetso bitari bimwe nka Creatine Kinase-MB (CK-MB) n'ibimenyetso by'uburwayi, biganisha ku kutamenya neza indwara. Irekurwa rya cTnT mu maraso nyuma yo kwangirika k'umutima ni umwihariko cyane ku kwangirika kw'imitsi y'umutima. Kuza kw'isuzuma rya troponin T (hs-cTnT) ryarushijeho guhindura uru rwego. Ibi bipimo bishobora kumenya ubwiyongere buto bwa cTnT buri munsi y'umupaka wa 99 ku ijana w'abaturage basanzwe. Ibi bituma abaganga bamenya imvune z'umutima hakiri kare cyane—akenshi mu masaha 1-3 nyuma yo kwitabazwa mu bitaro byihutirwa—bituma habaho kwihutisha no gupima MI vuba kandi vuba. Ibi byihutisha ubuvuzi bw'ukuri kandi bigasezerera abarwayi bafite ibyago bike, binoza imikorere y'ibitaro byihutirwa n'umuvuduko w'abarwayi.

Uretse gusuzuma indwara, cTnT igira uruhare runini mu gushyira mu byiciro ibyago no kumenya niba indwara ishobora kugaragara. Ubunini bw'ubwiyongere bwa cTnT bufitanye isano rikomeye n'ingano y'ibyangiritse by'umutima kandi ni ikimenyetso gikomeye cyerekana ingaruka mbi z'igihe gito n'igihe kirekire, harimo gucika intege k'umutima, guhagarara k'umutima, n'impfu. Ndetse n'ubwiyongere buke budakira buboneka mu isuzuma rya hs-cTnT ku barwayi basa n'abahagaze neza bushobora kumenya abafite imvune z'umutima zidakunze kugaragara, bikaba bigaragaza ibyago byinshi byo guhura n'indwara z'umutima mu gihe kizaza. Ibi bituma cTnT iba igikoresho cy'agaciro atari mu bihe bikomeye gusa ahubwo no mu kuvura indwara zidakira nk'indwara zidakira z'imitsi y'umutima, gucika intege k'umutima, n'indwara zidakira z'impyiko.

Byongeye kandi, gupima cTnT biyobora mu gufata ibyemezo by'ingenzi mu buvuzi. Uburyo cTnT izamuka cyangwa igabanuka ni ingenzi kugira ngo hamenyekane MI ikabije hakurikijwe amabwiriza rusange. Uku kwemeza biochemical gutanga amakuru ataziguye ku bikorwa byihutirwa nko gupima umutima no gusubiza imitsi mu maraso (PCI cyangwa CABG). Bifasha kandi mu guhitamo no gukurikirana imikorere y'imiti, harimo imiti ikomeye igabanya platelet (urugero: ticagrelor, prasugrel) n'imiti igabanya amaraso.

Akamaro ka cTnT kagera no ku ndwara z'umutima zitarimo insemike. Ingano iri hejuru igaragara mu ndwara zitandukanye aho habaho gukomereka k'umutima cyangwa imvune, nko kubabara umutima, kugabanuka k'umutima, sepsis ikomeye, kugongana kw'ibihaha bitera gukomereka k'umutima iburyo, ndetse n'uburozi bw'umutima buterwa na chimiotherapie. Muri ibi bihe, cTnT ikora nk'ikimenyetso cy'ubwiyongere bw'indwara z'umutima, bigatuma hakorwa iperereza ryimbitse kandi hagakorwa uburyo bukwiye bwo kuvura.

Mu gusoza, Cardiac Troponin T yahinduye cyane imikorere y’indwara z’umutima. Impinduka zayo mu gupima indwara z’umutima zatumye ikomera nk’ikimenyetso cy’ingenzi cy’indwara z’umutima. Binyuze mu gutanga uburyo bwo gusuzuma indwara, amakuru akomeye yerekeye ibyabaye, n’ubuyobozi bw’ingenzi mu kuvura indwara zikiza ubuzima, cTnT ni ingenzi cyane mu kunoza imikorere y’abarwayi haba mu bihe by’ubutabazi bw’indwara z’umutima ndetse no mu gihe kirekire cyo kuvura indwara z’umutima. Igipimo cyayo ni igipimo kidasubirwaho mu buvuzi bw’indwara z’umutima muri iki gihe.