Interleukin-6 ipolypeptide ine macheni maviri eglycoprotein, ane huremu hwemamorekuru e130kd. Senhengo yakakosha ye cytokine network, interleukin-6 (IL-6) inoita basa guru mu acute inflammatory reaction, uye inogona kutungamira acute phase reaction yechiropa, uye kukurudzira kugadzirwa kweC-reactive protein (CRP) ne fibrinogen. Zvirwere zvakawanda zvinotapukira zvinogona kukonzera kukwira kwe serum IL-6 level, uye IL-6 level inobatanidzwa zvakanyanya nemigumisiro yemurwere. Se pleiotropic cytokine ine mabasa akakura, IL-6 inoburitswa ne T cell, B cell, mononuclear phagocyte, uye endothelial cell, uye chikamu chakakosha che inflammatory mediator network. Kana paine inflammatory reaction, IL-6 inotanga kugadzirwa, izvo zvinokonzeresa kugadzirwa kweCRP ne procalcitonin (PCT) pakugadzirwa kwayo. Ichagadzirwa nekukurumidza kana paine hutachiona, kukuvara kwemukati nekunze, kuvhiyiwa, stress reaction, brain death, tumorigenesis, uye acute inflammatory reaction process yemamwe mamiriro ezvinhu. IL-6 inobatanidzwa mukuvapo uye kukura kwezvirwere zvakawanda, huwandu hwayo muropa hunobatanidzwa zvakanyanya nekuzvimba, hutachiona hwehutachiona uye chirwere che autoimmune, uye shanduko dzayo dzinoitika CRP isati yasvika. Zvichienderana nemhedzisiro yekutsvagisa, huwandu hweIL-6 hunowedzera nekukurumidza kana paine hutachiona hwebhakitiriya, huwandu hwePCT hunokwira mushure memaawa maviri, nepo CRP inongowedzera nekukurumidza mushure memaawa matanhatu. Kuburitswa kusingajairika kana kuratidzwa kwemajini kweIL-6 kunogona kutungamira mukuitika kwezvirwere zvakasiyana-siyana, huwandu hwakawanda hweIL-6 hunogona kuburitswa muropa kana paine chirwere, uye kuonekwa kweIL-6 kwakakosha zvikuru pakuongororwa kwechirwere uye kutonga kwekufanotaura.