Kukosha kweKuwanikwa kweHP-AG: Dombo rePakona muGastroenterology yemazuva ano

Kuonekwa kweHelicobacter pylori (H. pylori) antigen mutsvina (HP-AG) kwave kushandiswa senzira isingakuvadzi, yakavimbika zvikuru, uye inokosha pakurapa zvirwere zvemudumbu. Kukosha kwayo kunosanganisira kuongororwa kwezvirwere, kuongororwa mushure mekurapwa, uye kuongororwa kwehutano hweveruzhinji, zvichipa mabhenefiti akasiyana pane dzimwe nzira dzekuyedza.

Kukosha Kwekuongorora: Kururama uye Kureruka
Pakuongororwa kwekutanga kwehutachiona hweH. pylori, bvunzo dzeantigen dzetsvina, kunyanya idzo dzinoshandisa ma antibodies e monoclonal, ikozvino dzakurudzirwa senzira yekutanga yekuongorora mumitemo mikuru yepasi rose (semuenzaniso, Maastricht VI/Florence Consensus). Kunzwa kwavo uye kujeka kwavo kunokwikwidzana nekweyero yegoridhe yechinyakare, bvunzo yekufema yeurea (UBT), inowanzo pfuura 95% mumamiriro ezvinhu akanaka. Kusiyana ne serology, iyo inoona ma antibodies anoramba aripo kwenguva refu mushure mehutachiona, kuongororwa kweHP-AG kunoratidza hutachiona huripo. Izvi zvinoita kuti ive sarudzo iri nani yekuona kuti ndiani anoda kurapwa kwekubvisa. Uyezve, ndiyo yega bvunzo isingapindike inokurudzirwa yekushandisa muvana uye munzvimbo idzo UBT isingawanikwe kana isingashande. Kureruka kwayo - inoda sampuro diki yetsvina - inobvumira kuunganidzwa kuri nyore, kunyangwe kumba, zvichiita kuti kuongororwa kwakakura uye kuongororwa kuongororwe.

Basa Rakakosha Mukusimbisa Kubviswa Kwemutemo
Pamwe kushandiswa kwayo kwakanyanya ndiko kusimbisa kubviswa kwechirwere mushure mekurapwa. Mitemo iripo inotsigira zvakasimba nzira ye "kuyedza nekurapa" inoteverwa nekusimbiswa kwekubviswa kwechirwere. Bvunzo yeHP-AG yakakodzera basa iri, pamwe chete neUBT. Inofanira kuitwa mavhiki mana mushure mekupedza kurapwa nemishonga inorwisa mabhakitiriya kudzivirira mhedzisiro yenhema kubva muhuwandu hwebhakitiriya hwakaderedzwa. Kusimbisa kubviswa kwechirwere hakusi kungori tsika; zvakakosha kuve nechokwadi chekuti chirwere chegastritis chapera, kuongorora kubudirira kwekurapa mukudzivirira kudzoka kwechirwere, uye, chinonyanya kukosha, kuderedza njodzi yekenza yemudumbu inobatanidzwa neH. pylori. Kukundikana kwekurapa kwekutanga, kwakaonekwa kuburikidza nebvunzo yeHP-AG mushure mekurapwa, kunokurudzira shanduko muhurongwa, kazhinji kunosanganisira kuongororwa kwekugona kubatwa nechirwere.

Zvakanakira uye Rubatsiro rweHutano Hweveruzhinji
Bvunzo yeHP-AG ine zvakanakira zvakawanda. Inodhura zvishoma, haidi michina inodhura kana zvinhu zvinoonekwa seyakajairika, uye haikanganisike nemishonga yakaita seproton pump inhibitors (PPIs) kusvika padanho rakafanana neUBT (kunyange zvazvo maPPI achifanira kumbomiswa usati waongororwa kuti aone kana paine chokwadi). Haikanganisikewo nekusiyana kwenzvimbo mumabasa ebhakitiriya eurease kana chirwere chemudumbu (semuenzaniso, atrophy). Kubva pamaonero ehutano hwevanhu, nyore kushandisa kwayo kunoita kuti ive chishandiso chakanakisa chezvidzidzo zvezvirwere uye mapurogiramu makuru ekuongorora muvanhu vane huwandu hwakawanda hweH. pylori nekenza yemudumbu.

Miganhu uye Mamiriro Ezvinhu
Kunyange zvazvo zvichikosha zvikuru, kuongororwa kweHP-AG kune miganhu. Kubata sampuro nemazvo kwakakosha, uye huwandu hushoma hwebhakitiriya (semuenzaniso, mushure mekushandisa mishonga inorwisa mabhakitiriya kana PPI) kunogona kukonzera matambudziko enhema. Haipe ruzivo nezvekugona kubatwa nemishonga inorwisa mabhakitiriya. Saka, kushandiswa kwayo kunofanirwa kuenderana nemirairo yekiriniki.

Mukupedzisa, kuonekwa kweHP-AG ibasa guru rekurapa kweH. pylori kwemazuva ano. Kururama kwayo pakuongorora hutachiona, basa rayo guru pakusimbisa kubudirira kwayo mukubvisa chirwere, uye kushanda kwayo zvinosimbisa chinzvimbo chayo seyedzo yekutanga, isingapindi mishonga. Nekugonesa kuongororwa kunobudirira uye humbowo hwekurapwa, inobatsira zvakananga mukuvandudza mhedzisiro yemurwere, kudzivirira matambudziko, uye kusimudzira kuedza kwepasi rose kuderedza mutoro wezvirwere zvine chekuita neH. pylori, kusanganisira chirwere chemaronda emudumbu nekenza yemudumbu.

Isu baysen rapid test tinogona kupabvunzo ye antigen ye hp-agneruzivo rwemhando yepamusoro uye rwehuwandu. Ingotaura nesu kana muine kufarira!