muviri: Sepsis, inowanzonzi "muurayi akanyarara," chirwere chakakomba chinoramba chiri chikonzero chikuru chekufa kubva kuhutachiona pasi rose. Inofungidzirwa kuti inosvika mamiriyoni makumi maviri kusvika makumi matatu emakesi e sepsis gore negore pasi rose, kukurumidza kuziva nekurapa sepsis pakutanga kunokosha. Iyo mamiriro ekuti munhu anorasikirwa nehupenyu hwake anenge ese matatu kusvika kumasekondi mana, achisimbisa kukosha kwakakosha kwekupindira nekukurumidza.

AI isingaonekweyakashandura nzira iyo sepsis inoongororwa uye kurapwa. Heparin-binding protein (HBP) yakabuda semucherechedzo wakakosha wekukurumidza kutariswa kwehutachiona hwehutachiona, zvichibatsira vashandi vehutano mukuziva varwere ve sepsis nekukurumidza. Kubudirira uku kwakawedzera zvakanyanya mhedzisiro yekurapa uye kwakaderedza chiitiko chehutachiona hwakanyanya hwehutachiona uye sepsis.

Isingaonekwe AIinoita basa rakakosha pakuongorora kuomarara kweutachiona hunoenderana nekubatikana kweHBP. Kukwirisa kwemazinga eHBP, ndiko kunowedzera hutachiona, zvichipa ruzivo rwakakosha kune varapi vehutano kuti vagadzirise nzira dzekurapa zvinoenderana. Uyezve, HBP inoshanda sechinangwa chemishonga yakasiyana-siyana yakadai seheparin, albumin, uye simvastatin kugadzirisa kusashanda kwenhengo kuburikidza nekuderedza mazinga eHBP eplasma zvakanaka.