Kubudirira Kwekuedza Kusingapindi Munzvimbo:Calprotectin yetsvina"Anoyambuka Miganhu" Kubatsira Kuongororwa Kwekukurumidza Kwekuzvimba Kwemudumbu Muvana

Mukuongorora zvirwere zvemudumbu zvevana, endoscopy yagara iri "nzira yakanaka" yekuona kuzvimba kwemudumbu. Zvisinei, kuongororwa uku kunopindirana hakungoperekedzwi nekusagadzikana kwemuviri kwevana, kunyanya vadiki, asiwo kunowanzounza kutya kukuru kwepfungwa uye kuoma kushanda pamwe chete. Izvi zvinoita kuti vabereki vazhinji vazeze panguva yekutanga kuongororwa uye vanogona kushaya mukana wekupindira nekukurumidza. Munguva pfupi yapfuura, tsvakiridzo itsva yekiriniki uye tsika yekushandisa yaunza nhau dzinonakidza:fecal calprotectin (FCP), chiratidzo chekare chisingapindi chirwere chekuongorora zvirwere zvemudumbu, chiri kuratidza mukana mukuru mukuongorora kwekutanga kuzvimba kwemudumbu muvana, zvichiita kuti pave ne "crossover" inoshamisa kubva "mudumbu rezasi" kuenda "mudumbu repamusoro".

Kubva Padambudziko re "Gold Standard" Kusvika Pakuvamba Kwekuyedzwa Kusingapindire

Kuzvimba kwemudumbu kwepamusoro senge gastritis ne gastroduodenitis hazviwanzoitika kuvana, uye zvikonzero zvacho zvinosanganisira hutachiona, mishonga, uye kushushikana. Pachivanhu, kuongororwa kunoda kuongororwa nemaziso uye kuongororwa kwenyama kuburikidza ne gastroscopy, inova nzira yakaoma uye inokuvadza. Nzira dzisingakuvadzi uye dziri nyore dzekuona dzagara dziri tarisiro yakajairika yevanachiremba nemhuri dzevana vane chirwere ichi.Calprotectin yetsvinaipuroteni inoratidza kuunganidzwa kwe neutrophil. Kana mucosa yemudumbu yazvimba, huwandu hwayo hunowedzera zvakanyanya. Kwemakore, yave ichishandiswa zvakanyanya mukuongorora mashandiro echirwere chemudumbu chinoputika (IBD) uye kuongororwa kwakasiyana kwe irritable bowel syndrome (IBS), kunyanya pakuzvimba kwemudumbu.

Tsvagiridzo yesainzi inosimbisa hwaro hwakasimba hwekushandiswa kwe "kuyambuka miganhu"

Ongororo dziri kuramba dzichiwedzera dzinoratidza kuti chiratidzo ichi chekuzvimba hachisi chemuura chete. Kana kuzvimba kukaitika mudumbu repamusoro (senge mudumbu neduodenum), masero ekuzvimba anopindawo nekuburitsa.calprotectinPuroteni iyi inofamba ichidzika nemudumbu pamwe chete nemvura yekugaya chikafu uye zvasara zvekudya, zvichizoonekwa mutsvina. Ongororo dzichangobva kuitwa muvana dzakaratidza kuticalprotectin yetsvinamazinga akakwira zvakanyanya muvana vane gastritis kana duodenitis yakasimbiswa ne endoscopically zvichienzaniswa nevaya vane dyspepsia inoshanda kana kuwanikwa kwe endoscopic kwakajairika. Kunyangwe huwandu hwakakwira hweFC hunokonzerwa nekuzvimba kwemudumbu hwepamusoro hunowanzo kuve hwakaderera pane hwevane IBD inoshanda, hwakaratidza mutsauko wakakosha muhuwandu kana huchienzaniswa nevanhu vane hutano. Izvi zvinoratidza kuti bvunzo dzeFC dzinogona kushandiswa senzira inoshanda yekuongorora vana kuti vaone vana vari panjodzi huru yekuzvimba kwemudumbu kweorganic pakati pevana vazhinji vane zviratidzo zvakaita sekurwadziwa mudumbu, kuzvimba, uye kuda kurutsa.

Kukosha kweKliniki: Kuvaka Nzira Iri Nani Yekuongorora Vana

Kushandiswa kwecalprotectin yetsvinaKwakaunza mabhenefiti akawanda mukuongorora nekurapa zvirwere zvemudumbu muvana:

1. Hazvipindi uye zvinotevedzera mitemo yakawanda: Zvinongodiwa sampuli shoma yetsvina, uye maitiro acho haapindi zvachose, izvo zvinoderedza mutoro wemuviri nepfungwa pavana. Vabereki vanogamuchira zvikuru maitiro aya, zvichiita kuti zvive nyore kukurumidza kuita ongororo inodzokororwa mumakiriniki ekunze.
2. Chishandiso chinoshanda chekuongorora nekuchenesa: Kune vana vane zviratidzo zvemudumbu zvinoramba zvichiitika,Calprotectin yetsvinabvunzo dzinogona kuitwa kutanga kuti pave nekusiyanisa zvinobudirira pakati pezvirwere zvinozvimba uye zvirwere zvinoshanda.Calprotectin yetsvinamazinga akajairika, zvinhu zvinoshanda zvinogona kutariswa pakutanga kana kurapwa kwakaitwa nenyanzvi uye kuongororwa kunogona kuitwa. Kana mazinga eFC akakwira, zvinopa hwaro hwakasimba hwekuita gastroscopy inopararira, kudzivirira nzira dze endoscopic dzisina basa uye kugadzirisa kugoverwa kwezviwanikwa zvehutano.
3. Kubatsirwa kuongorora kushanda uye kudzoka kwechirwere: Mushure mekuongororwa kwekuzvimba kwemudumbu repamusoro uye kutanga kwekurapwa, kutarisa shanduko dziri kuitikaCalprotectin yetsvinamwero wechirwere unogona kushanda sechiratidzo chekutarisa kana kuzvimba kwaderera uye kana kurapwa kwacho kuri kushanda. Zvinogonawo kubatsira kuona kudzoka kwechirwere nekukurumidza.

Maonero Eramangwana

Ehe, kushandiswa kwefecal calprotectin mudumbu repamusoro kuchiri kuda tsvakiridzo yakawanda kuti inyatsotsanangura kukosha kwayo kwakakwana uye kubvisa zvimwe zvinhu zvemudumbu zvinogona kukonzera kukwira kweFC. Zvisinei, senzira yakachengeteka, iri nyore, uye isingadhuri yekuongorora, pasina mubvunzo inovhura mukana mutsva wekuongorora nekukurumidza kuzvimba kwemudumbu wepamusoro muvana. Izvi zvinoratidza kufambira mberi mukuongorora zvirwere zvemudumbu zvevana kuenda kune nzira ine hunhu uye chaiyo. Tinotenda kuti nekuenderera mberi nekutsvaga kwakadzama uye ruzivo rwekiriniki rwakawanda,calprotectin yetsvina,"nyeredzi iyi inosanganisa zvipembenene," ichaita basa rakakosha mukuchengetedza hutano hwekugaya kwevana.

Baysen Medical inogara ichinyanya kutarisa pakuongorora kuti hupenyu huve nani. Takagadzira mapuratifomu mashanu etekinoroji - Latex, colloidal gold, Fluorescence Immunochromatographic Assay, Molecular, Chemiluminescence Immunoassay. Tine Colloidal Gold.Calprotectin yetsvina Kiti yekuyedza uye Fluorescence ImmunoassayKiti yekuyedza yeCalprotectinyekuyedza