Chirwere cheCoronavirus 2 (Severe acute respiratory syndrome 2 (SARS-CoV-2), chirwere chinokonzera denda reCoronavirus ra2019 (COVID-19), ihutachiona hweRNA hune tambo imwe chete, hune genome size inosvika 30 kb. Mhando dzakawanda dzeSARS-CoV-2 dzine zviratidzo zvakasiyana zvemutachiona dzakabuda mudenda rese. Zvichienderana nekukura kweprotein mutation landscape, dzimwe mhando dzakaratidza kutapurirana kwakanyanya, kutapurirana, uye hutachiona.

Rudzi rweBA.2.86 rweSARS-CoV-2, rwakatanga kuzivikanwa muna Nyamavhuvhu 2023, rwakasiyana nerudzi rweOmicron XBB rwuri kupararira pari zvino, kusanganisira EG.5.1 neHK.3. Rudzi rweBA.2.86 rune shanduko dzinopfuura makumi matatu muprotein yespike, zvichiratidza kuti rudzi urwu runokwanisa kudzivirira dziviriro yehutachiona hweSARS-CoV-2.

JN.1 (BA.2.86.1.1) ndiyo mhando yeSARS-CoV-2 yakabuda munguva pfupi yapfuura yakabva kurudzi rweBA.2.86. JN.1 ine shanduko huru yeL455S mupuroteni yespike uye mamwe matatu ekuchinja mumapuroteni asiri espike. Zvidzidzo zviri kuongorora HK.3 nedzimwe mhando dze "FLip" zvakaratidza kuti kuwana shanduko yeL455F mupuroteni yespike kunobatanidzwa nekuwedzera kwekutapurirana kwehutachiona uye kugona kudzivirira immune system. Kuchinja kweL455F neF456L kune zita remadunhurirwa rekuti ""Flip"shanduko dzemuviri nekuti dzinochinja nzvimbo dzemaamino acid maviri, akanyorwa kuti F naL, papuroteni inonzi spike.

Isu veBaysen Medical tinogona kupa bvunzo yeCOVID-19 yekushandisa kumba, tinokugamuchirai kuti mutibate kuti muwane rumwe ruzivo.