Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), e leng kokoana-hloko e bakang seoa sa morao tjena sa lefu la coronavirus la 2019 (COVID-19), ke kokoana-hloko ea RNA e nang le moelelo o motle, e nang le mothapo o le mong e nang le boholo ba genome bo ka bang 30 kb. Mefuta e mengata ea SARS-CoV-2 e nang le matšoao a fapaneng a phetoho e hlahile ho pholletsa le seoa. Ho latela sebaka sa bona sa phetoho ea protheine e matla, mefuta e meng e bontšitse phetiso e phahameng, tšoaetso le bokhopo.

Leloko la BA.2.86 la SARS-CoV-2, le ileng la hlwauwa ka lekgetlo la pele ka Phato 2023, le fapane ka tlhaho le meloko ya Omicron XBB e ntseng e potoloha hona jwale, ho kenyeletswa le EG.5.1 le HK.3. Leloko la BA.2.86 le na le diphetoho tse fetang 30 protheineng ya spike, e leng se bontshang hore leloko lena le kgona haholo ho qoba boitshireletso ba mmele bo seng bo ntse bo le teng ba anti-SARS-CoV-2.

JN.1 (BA.2.86.1.1) ke mofuta o sa tsoa hlaha oa SARS-CoV-2 o tsoileng lelokong la BA.2.86. JN.1 e na le phetoho e ikhethang ea L455S protheineng ea spike le liphetoho tse ling tse tharo liprotheineng tse seng tsa spike. Lithuto tse batlisisang HK.3 le mefuta e meng ea "FLip" li bontšitse hore ho fumana phetoho ea L455F protheineng ea spike ho amahanngoa le keketseho ea phetiso ea vaerase le bokhoni ba ho qoba sesole sa 'mele. Liphetoho tsa L455F le F456L li bitsoa ""Phetla”diphetoho tsa lefutso hobane di fetola maemo a di-amino acid tse pedi, tse ngotsweng F le L, protheineng e hlabang.

Re baysen medical re ka fana ka tlhahlobo ea covid-19 bakeng sa tšebeliso ea lapeng, rea u amohela ho ikopanya le rona bakeng sa lintlha tse ling.