UKUSETYENZISWA OKUJOLISWEYO

Isixhobo sokuxilonga sasimahla I-Prostate Specific Antigen (uvavanyo lwe-fluorescence immunochromatographic) luvavanyo lwe-fluorescence immunochromatographic lokufumanisa ubungakanani be-Prostate Specific Antigen (fPSA) yasimahla kwi-serum okanye kwi-plasma yomntu. Umlinganiselo we-fPSA/tPSA ungasetyenziswa ekuxilongweni komhlaza we-prostate kunye ne-benign prostatic hyperplasia. Zonke iisampulu ezilungileyo kufuneka ziqinisekiswe zezinye iindlela. Olu vavanyo lwenzelwe ukusetyenziswa ziingcali zonyango kuphela.

ISISHWANKATHELO

I-antigen ye-prostate-specific antigen (fPSA) yi-antigen ye-prostate-specific ekhutshwa egazini ngendlela ekhululekileyo kwaye ikhutshwa ziiseli ze-prostate epithelial. I-PSA (Prostate Specific Antigen) yenziwe kwaye ikhutshwe ziiseli ze-prostate epithelial kwi-semen kwaye yenye yezona zinto ziphambili ze-plasma yesiminal. Iqulethe ii-amino acid residues ezingama-237 kwaye ubunzima bayo be-molecular bumalunga ne-34kD. Inomsebenzi we-serine protease we-single chain glycoprotein, ithatha inxaxheba kwinkqubo yolwelo lwe-semen. I-PSA egazini sisiphumo se-PSA ekhululekileyo kunye ne-PSA edibeneyo. Amanqanaba e-plasma yegazi, kwi-4 ng/mL yexabiso elibalulekileyo, i-PSA kumhlaza we-prostate Ⅰ ~ Ⅳ ixesha lobuthathaka be-63%, 71%, 81% kunye ne-88% ngokwahlukeneyo.