UKUSETYENZISWA OKUJOLISWEYO

Ikhithi yokuxilongangenxaI-Triiodothyronine iyonke(uvavanyo lwe-fluorescence immunochromatographic) luvavanyo lwe-fluorescence immunochromatographic lokufumanisa ubungakanani be-Total Triiodothyronine (TT3) kwi-serum okanye kwi-plasma yomntu, esetyenziswa kakhulu ukuvavanya umsebenzi we-thyroid. Luyi-reagent yokuxilongwa encedisayo. Zonke iisampulu ezilungileyo kufuneka ziqinisekiswe zezinye iindlela. Olu vavanyo lwenzelwe ukusetyenziswa ziingcali zonyango kuphela.

ISISHWANKATHELO

Ubunzima bemolekyuli yeTriiodothyronine (T3) yi-651D. Yeyona ndlela iphambili esebenzayo yehomoni ye-thyroid. I-T3 iyonke (i-T3 iyonke, i-TT3) kwi-serum yahlulwe ngokweentlobo zokubopha kunye neentlobo ezikhululekileyo. I-99.5% ye-TT3 ibopha kwi-serum Iiproteni ze-Thyroxine Binding (TBP), kwaye i-T3 yasimahla (i-T3 yasimahla) ibandakanya i-0.2 ukuya kwi-0.4%. I-T4 kunye ne-T3 zithatha inxaxheba ekugcineni nasekulawuleni umsebenzi we-metabolic yomzimba. Ukulinganiswa kwe-TT3 kusetyenziswa ukuvavanya imeko yokusebenza kwe-thyroid kunye nokuchonga izifo. I-TT3 yeklinikhi luphawu oluthembekileyo lokuchonga kunye nokujongwa ngempumelelo kwe-hyperthyroidism kunye ne-hypothyroidism. Ukuchonga i-T3 kubaluleke ngakumbi ekuchongeni i-hyperthyroidism kune-T4.