I-Cal yi-heterodimer, eyenziwe yi-MRP 8 kunye ne-MRP 14. Ifumaneka kwi-neutrophils cytoplasm kwaye ibonakaliswa kwiimembrane zeseli ze-mononuclear. I-Cal yiprotheni yesigaba esibukhali, inesigaba esizinzileyo malunga neveki enye kwilindle lomntu, ifunyaniswa ukuba luphawu lwesifo samathumbu esivuthayo. Le khithi luvavanyo olulula, olubonakalayo olulinganiselayo olubona i-cal kwilindle lomntu, lunobuntununtunu bokufumanisa obuphezulu kunye nobuchwephesha obuqinileyo. Uvavanyo olusekelwe kwi-high specificit double antibodies sandwich reaction principle kunye ne-gold immunochromatographic assay analysis techniques, lunokunika iziphumo kwimizuzu eli-15.