umzimba: I-Sepsis, edla ngokubizwa ngokuba "ngumbulali othuleyo," sisifo esiyingozi esihlala singunobangela wokufa ngenxa yosulelo kwihlabathi liphela. Kuqikelelwa ukuba i-20 ukuya kwi-30 yezigidi zeemeko ze-sepsis minyaka yonke kwihlabathi jikelele, ukungxamiseka ekuchongeni nasekuphatheni i-sepsis kwangethuba kubaluleke kakhulu. Yimeko apho umntu elahlekelwa ubomi bakhe phantse yonke i-3 ukuya kwi-4 imizuzwana, egxininisa imfuno ebalulekileyo yokungenelela ngokukhawuleza.

I-AI engabonakaliyoiye yatshintsha indlela yokufunyaniswa nokunyangwa kwe-sepsis. Iprotheyini ye-Heparin-binding (HBP) iye yavela njengophawu oluphambili lokufunyanwa kwangoko usulelo lwebhaktheriya, ukunceda abaqeqeshi bezempilo ekuchongeni izigulane ze-sepsis ngokukhawuleza. Olu phuhliso luye lwaphucula kakhulu iziphumo zonyango kunye nokunciphisa iziganeko zentsholongwane enzima yebhaktheriya kunye ne-sepsis.

I-AI engabonakaliyoidlala indima ebalulekileyo ekuvavanyeni ubuzaza bosulelo ngokusekelwe kugxininiso lwe-HBP. Okukhona aphezulu amanqanaba e-HBP, kokukhona usulelo luqatha, lunika ulwazi oluxabisekileyo kubaboneleli bezempilo ukuze balungelelanise izicwangciso zonyango ngokufanelekileyo. Ukongezelela, i-HBP isebenza njengenjongo yeziyobisi ezahlukeneyo ezifana ne-heparin, i-albumin, kunye ne-simvastatin ukujongana nokungasebenzi kakuhle kwamalungu ngokunciphisa amanqanaba e-plasma e-HBP ngokufanelekileyo.