Ukuhlolwa Kwangethuba, Uxolo Lwengqondo: Ukuqonda i-HCV kunye neeTekhnoloji ezimbini Eziphambili Zokufumanisa Okukhawulezayo

Intsholongwane yeHepatitis C (HCV) Usulelo yingxaki yempilo yoluntu kwihlabathi liphela. Idluliselwa kakhulu ngegazi, kwaye usulelo lwasekuqaleni ludla ngokubonisa iimpawu ezingenazimpawu, nto leyo eshiya abantu abaninzi abasulelekileyo bengazi ngemeko yabo. Nangona kunjalo, intsholongwane yonakalisa isibindi buthule, nto leyo enokubangela ukuba iqhubekele phambili ibe yi-fibrosis yesibindi, i-cirrhosis, kwanomhlaza wesibindi. Ke ngoko, ukuxilongwa kwangoko kunye nokuxilongwa ngamanyathelo okuqala abalulekileyo ekumiseni ukuqhubela phambili kwesifo kunye nokuphucula amazinga okunyanga.

Okwangoku, okokuqalaI-HCV Ukuhlolwa kuxhomekeke kakhulu ekufumaneni ubukhoI-HCVii-antibodies egazini. Ngokuhambela phambili kwetekhnoloji, iindlela zokuvavanya ezilula nezikhawulezayo ziye zenza kube lula kakhulu ukuphonononga, phakathi kwazo ii-colloidal gold assays kunye nee-fluorescent immunoassay reagents ziiteknoloji ezimbini eziphambili ezisetyenziswa kakhulu.

Uvavanyo lweColloidal Gold Rapid: "IScout" ekhawulezayo nelula

Indlela yegolide ye-colloidal yiteknoloji esetyenziswa kakhulu kwinto esiyibiza ngokuba yi-"rapid test." Umgaqo wayo oyintloko ubandakanya ukusebenzisa ii-nanoparticles zegolide ezilungiselelwe ngokukodwa njengee-tracers.I-HCV Ii-antibodies zikhona kwisampulu, zibopha ngokukodwa kwii-antigens ezilungiselelwe kwangaphambili kwi-reagent kwaye ziqokelelane kumgca wovavanyo, nto leyo ebangela ukuba amasuntswana egolide angabonakaliyo ekuqaleni ahlangane aze enze ibhendi ebomvu ecacileyo.

Iingenelo ezinkulu zale ndlela zezi:

1) Isantya:Isantya sinokuvavanywa ngokubonakalayo kwimizuzu eli-15-20.

2) Kulula ukuyisebenzisa:Akukho zixhobo zinzima zifunekayo; abasebenzi abaqeqeshiweyo banokugqibezela inkqubo kwiindawo zonyango lwempilo eziphambili okanye kwiindawo ezithile zokufakelwa.

3) Uzinzo oluhle:Ii-reagents zihlala zigcinwa kwaye zithuthwe kubushushu begumbi.

Ke ngoko, uvavanyo lwe-colloidal gold rapid lufanelekile kakhulu kuvavanyo lokuqala olukhulu, uvavanyo olungxamisekileyo, kunye novavanyo lokuqala kwiindawo ezinezibonelelo zonyango ezinqongopheleyo, nto leyo echonga ngokufanelekileyo abantu abanokuba nentsholongwane kuluntu.

I-Fluorescent Immunoassay Diagnostic Reagent: "Uhlalutyo" Olunovelwano Noluchanekileyo

Uvavanyo lwe-fluorescent immunochromatographic lubonisa uphuculo olubalulekileyo kwitekhnoloji ye-chromatography yendabuko. Lusebenzisa ii-microspheres ezikhethekileyo ze-fluorescent njengeempawu. Emva kokuba kwenzeke i-antigen-antibody reaction, izinto ze-fluorescent eziqokelelwe kumgca wovavanyo zikhupha isignali ebonakalayo ye-fluorescent xa zivuselelwa ngumthombo othile wokukhanya.

Xa kuthelekiswa nendlela yegolide ye-colloidal, iimpawu zayo eziphambili zezi:

1) Isaziso Esiphezulu kunye noMgangatho weWaveform:Iyakwazi ukubona ukumelana okuqinileyo, nto leyo ekhokelela kwiziphumo ezichanekileyo ngakumbi kwaye inciphise ngempumelelo umngcipheko wokufunyanwa okungachanekanga kunye neempembelelo ezingezizo.

2) Uhlalutyo lobungakanani:Ukufunda ubunzulu be-fluorescence usebenzisa isixhobo esikhethekileyo sokubona ukukhanya kunika ulwazi oluthe kratya malunga nokubona ukukhanya.

3) Ifanelekile ngakumbi kwi-automation:Idibana ngokulula nezixhobo zokufumanisa, iphucula ukusebenza kakuhle kovavanyo lweebhetshi kwiilabhoratri.

Ii-reagents ze-fluorescent immunoassay zisetyenziswa kakhulu kwizibhedlele, kumasebe elebhu, kumaziko olawulo lwezifo, okanye kwiilebhu zovavanyo lomntu wesithathu. Zisebenza njengoqinisekiso olongezelelweyo lweesampuli ezakha zabonakala okanye zisetyenziswa ngokuthe ngqo kwiimeko zovavanyo lweklinikhi ezifuna ukuchaneka okuphezulu.

Isishwankathelo

Nokuba luvavanyo lwegolide olusebenzisa i-colloidal, isixhobo esinamandla sokuhlola ngokukhawuleza, okanye uvavanyo lwe-fluorescent immunoasses, ukuqinisekiswa ngokuchanekileyo kwendlela ekhethwayo, zombini zizixhobo ezibalulekileyo ekulweni ne-hepatitis C. Ukukhetha indlela kuxhomekeke kwimeko ethile yokusetyenziswa, izixhobo ezikhoyo, kunye neemfuno zovavanyo.

I-Baysen Medical isoloko igxile kwindlela yokuxilonga ukuphucula umgangatho wobomi. Siphuhlise amaqonga etekhnoloji ama-5- iLatex, igolide ye-colloidal, uvavanyo lwe-Fluorescence Immunochromatographic, i-Molecular, i-Chemiluminescence Immunoassay, i-OurUvavanyo lwe-HCV olukhawulezayoKwayeI-reagent ye-HCV FIA Kulula ukuyisebenzisa kwaye ingafumana iziphumo zovavanyo kwimizuzu eli-15