Uvavanyo lwe-IgE olupheleleyo luchonga njani izinto ezibangela i-allergy?

Ngaba uhlala ufumana amaqhuqhuva aphindaphindayo, i-rhinitis, okanye ukuphefumla ngequbuliso? Ezi ngxaki zinokuthi zikhombe kumthombo omnye—ii-allergies. Imizimba yethu ine-"inkqubo yokuxilonga" enobuchule, kwayeI-IgE iyonkeyinxalenye ebalulekileyo. Ukuqondaiyonke i-IgEUvavanyo lusenokuba linyathelo lakho lokuqala ekutyhileni imfihlakalo yezinto ezingadibaniyo neziyobisi.

Yintoni iI-IgE iyonke?

I-Immunoglobulin E (IgE) yeyona antibody incinci kakhulu kwi-serum. Uxinzelelo lwe-IgE kwi-serum luyiezinxulunyaniswa nobudala, apho amaxabiso aphantsi alinganiswa ekuzalweni. Ngokubanzi, amagqabi e-lgE abantu abadalaifunyenwe xa ineminyaka emi-5 ukuya kweyesi-7 ubudala. Phakathi kweminyaka eli-10 neli-14 ubudala, amanqanaba e-IgE anokuba phezulu kuneabo kubantu abadala. Emva kweminyaka engama-70 ubudala, amanqanaba e-IgE anokwehla kancinci aze abe phantsi kunamanqanaba abonwayokubantu abadala abangaphantsi kweminyaka engama-40 ubudala.
Nangona kunjalo, inqanaba eliqhelekileyo le-IgE alinakukwazi ukuthintela izifo ze-allergy. Ke ngoko, kwisifo esahlukileyokwizifo ze-allergy kunye nezifo ezingezizo ze-allergy, ukuchonga ubungakanani benqanaba le-IgE kwi-serum yomntu kuyasebenza kuphela.ukubaluleka xa kusetyenziswa kunye nezinye iimvavanyo zeklinikhi.

I-IgE iyonkeUvavanyo: "I-Navigator" yokufumanisa i-Allergy

I-IgE iyonke iyasebenza ekufumaneni I-Immunoglobulin E iyonke (T-IgE)kwiisampuli zegazi/plasma/zegazi elipheleleyo ebantwini. Nangona ingenakukwazi ukumisela ngokuthe ngqo ukuba yeyiphi into ethile ebangela i-allergy, ibaluleke kakhulu ekuxilongweni kwezifo ze-allergy:

1. Uvavanyo oluncedisayo:Iphakanyisiweyoiyonke i-IgEinqanaba libonisa ngamandla ukuba kukho i-allergy okanye usulelo lwe-pathogen, nto leyo ebonisa ugqirha indlela yokuvavanya ngakumbi.

2. Uvavanyo loMngcipheko kunye neNgxakiy: Ngokubanzi, ixabiso eliphezuluiyonke i-IgEinqanaba libonisa ukuba kukho i-allergy engakumbi, nto leyo enceda ekuvavanyeni ubukhali kunye nomngcipheko wokuhlaselwa zizifo ezifana ne-asthma.

3. Uxilongo lokwahluka: Inceda ukwahlula phakathi kwezifo ze-allergy (ezifana ne-allergy rhinitis) kunye nezifo ezingezizo ze-allergy (umz., i-vasomotor rhinitis).

4. Ukujonga ukusebenza kakuhle koNyango: Ukubekwa esweni rhoqo kweiyonke i-IgEutshintsho ngexesha lonyango lokunciphisa uvakalelo okanye ukungenelela ngamayeza lunokuvavanya ngokungathanga ngqo isiphumo sonyango.

Ngubani ofuna ukufunyanwa kwe-Total IgE?

Kucetyiswa ukuba abantu abanezi meko zilandelayo badibane nogqirha ukuze babone ukuba iyonke i-IgE tKuyacetyiswa ukuba u-esting:

1. Iimpawu ezirhanelekayo zokunganyamezelani (i-eczema, i-urticaria/ii-hives, i-allergy rhinitis, i-asthma, njl.njl.)

2. Imbali ecacileyo yosapho malunga nee-allergies

3. Abantu abachaphazeleka kwimisebenzi ethile (umz., luthuli, iikhemikhali)

4. Uvavanyo lokuqala ngaphambi kokuba uqhubeke novavanyo oluthile lwe-allergen

Iingcebiso ezivela kwiBaysen Medical

Njengomvelisi ochwephesha wezixhobo zovavanyo lwezonyango, i-We Baysen Medical izimisele ukubonelela ngokuchanekileyo nangokuthembekileyoiyonke i-IgE Ii-reagents ze-Fia ezine-Reader-I-Wiz-A101 kwayeI-WIZ-A202,I-WIZ-A203, ukunceda amaziko ezempilo ekuchongeni iimpawu zokunganyamezelani ngokukhawuleza nangokuchanekileyo. Nangona kunjalo, into esifuna ukuyigxininisa ngakumbi kukuba ukunganyamezelani akulawuleki. Ngovavanyo lwesayensi ukucacisa imeko yomntu, nangaphantsi kwesikhokelo sikagqirha—ngokuphepha ukuvezwa yi-allergen, ukufumana unyango oluqhelekileyo, okanye unyango lokunciphisa uvakalelo—uninzi lweempawu zokunganyamezelani zinokulawulwa ngempumelelo.