I-C-peptide, eyaziwa ngokuba yi-linking peptide, yi-amino acid ebalulekileyo kwimveliso ye-insulin. Ikhutshwa yi-pancreas kunye ne-insulin kwaye isebenza njengophawu oluphambili lokuvavanya umsebenzi we-pancreatic. Ngelixa i-insulin ilawula amanqanaba eswekile egazini, i-C-peptide idlala indima eyahlukileyo kwaye ibalulekile ekuqondeni iimeko ezahlukeneyo zempilo, ingakumbi isifo seswekile. Ngokulinganisa amanqanaba e-C-peptide, ababoneleli bezempilo banokwahlula phakathi kohlobo 1 nohlobo 2 lwesifo seswekile, bakhokele izigqibo zonyango, kwaye bajonge ukusebenza kakuhle konyango.

Ukulinganisa amanqanaba e-C-peptide kubalulekile ekuxilongeni nasekulawuleni isifo seswekile. Abantu abanesifo seswekile sohlobo loku-1 badla ngokuba namanqanaba aphantsi okanye angaziwayo e-insulin kunye ne-C-peptide ngenxa yokuhlasela kwenkqubo yomzimba yokuzikhusela kwiiseli ze-beta ezivelisa i-insulin. Kwelinye icala, abantu abanesifo seswekile sohlobo lwesibini banokuba namanqanaba e-C-peptide aqhelekileyo okanye aphezulu kuba imizimba yabo ivelisa i-insulin kodwa ayichasani nemiphumo yayo. Ukubeka esweni amanqanaba e-C-peptide kwizigulana, njengabo bafakelwa iiseli ze-islet, kunokubonelela ngengcaciso ebalulekileyo malunga nempumelelo yeenkqubo zonyango.

Izifundo zikwaphonononge iziphumo ezinokubakho zokukhusela ze-C-peptide kwiithishu ezahlukeneyo. Olunye uphando lubonisa ukuba i-C-peptide inokuba neempawu zokulwa nokuvuvukala ezinokunceda ukunciphisa iingxaki ezinxulumene nesifo seswekile, njengokonakala kwemithambo-luvo kunye nezintso. Nangona i-C-peptide ngokwayo ingachaphazeli ngqo amanqanaba eswekile egazini, isebenza njenge-biomarker exabisekileyo yokulawula isifo seswekile kunye nokulungelelanisa izicwangciso zonyango ngokweemfuno zomntu ngamnye. Ukuba ufuna ukuphonononga nzulu ukuqonda isifo seswekile, ukuhlala unolwaziiindaba zoshishinoezinxulumene nokhathalelo lwempilo kunye nophuhliso lwezonyango zinokubonelela ngolwazi oluxabisekileyo kwiingcali kunye nezigulana.