Ikhithi Yokuxilonga ye-Heparin Binding Protein
Ulwazi lokukhiqiza
| Inombolo Yemodeli | I-HBP | Ukupakisha | Izivivinyo ezingu-25/ikhithi, amakhithi angu-30/i-CTN |
| Igama | Ikhithi Yokuxilonga ye-Heparin Binding Protein | Ukuhlukaniswa kwezinsimbi | Isigaba II |
| Izici | Ukuzwela okuphezulu, Ukusebenza okulula | Isitifiketi | I-CE/ ISO13485 |
| Ukunemba | > 99% | Isikhathi sokuphelelwa yisikhathi | Iminyaka Emibili |
| Indlela Yokwenza | Ukuhlolwa kwe-Fluorescence Immunochromatographic | Isevisi ye-OEM/ODM | Kuyatholakala |
Sebenzisa Ngokuhlosile
Le khithi iyasebenza ekutholakaleni kwe-heparin binding protein (HBP) ngaphakathi kwe-vitro kusampula yegazi/plasma yomuntu wonke,futhi ingasetshenziswa ekuxilongweni kwezifo ezisizayo, njengokwehluleka kokuphefumula nokujikeleza kwegazi, i-sepsis enzima,ukutheleleka komgudu womchamo ezinganeni, ukutheleleka kwesikhumba okubangelwa amagciwane kanye ne-meningitis ebangelwa amagciwane. Le khithi inikeza kuphelaimiphumela yokuhlolwa kwe-heparin binding protein, kanye nemiphumela etholakele kufanele isetshenziswe kanye neminye imiphumela yezokwelapha.ulwazi lokuhlaziya.
Inqubo yokuhlola
| 1 | I-1: Ukusetshenziswa kwe-analyzer yokuzivikela yomzimba ephathekayo |
| 2 | Vula iphakethe lesikhwama se-aluminium foil eline-reagent bese ukhipha idivayisi yokuhlola. |
| 3 | Faka idivayisi yokuhlola ngokuvundlile endaweni yokuhlaziya amasosha omzimba. |
| 4 | Ekhasini lasekhaya le-interface yokusebenza ye-immune analyzer, chofoza okuthi “Standard” ukuze ufake i-interface yokuhlola. |
| 5 | Chofoza okuthi “QC Scan” ukuze uskene ikhodi ye-QR ngaphakathi kwekhithi; amapharamitha ahlobene nekhithi yokufaka kuthuluzi bese ukhetha uhlobo lwesampula. Qaphela: Inombolo ngayinye yebhetshi yekhithi kufanele iskene kanye. Uma inombolo yebhetshi isiskene, khona-ke yeqa lesi sinyathelo. |
| 6 | Hlola ukuvumelana “kwegama lomkhiqizo”, “inombolo yeqoqo” njll. esibonakalayo sokuhlola ngolwazi oluselebula lekhithi. |
| 7 | Qala ukwengeza isampula uma ulwazi luhambisana:Isinyathelo 1: thatha isampula yegazi eliphelele eliyi-80μL kancane kancane, bese uqaphela ukuthi awekho amabhamuza e-pipette; Isinyathelo 2: isampula ye-pipette ukuze isampula i-diluent, bese uxuba kahle isampula nesampula i-diluent; Isinyathelo 3: isixazululo se-pipette esingu-80µL sixutshwe kahle emthonjeni wedivayisi yokuhlola, bese unaka amabhamuza e-pipette ngesikhathi sokuthatha amasampula |
| 8 | Ngemva kokwengeza okuphelele kwesampula, chofoza okuthi “Isikhathi” bese isikhathi esisele sokuhlola sizoboniswa ngokuzenzakalelayo ku-interface. |
| 9 | I-immune analyzer izoqedela ngokuzenzakalelayo ukuhlolwa nokuhlaziywa lapho isikhathi sokuhlolwa sesifikile. |
| 10 | Ngemva kokuthi ukuhlolwa yi-immune analyzer sekuqediwe, umphumela wokuhlolwa uzoboniswa ku-interface yokuhlola noma ungabukwa "ngomlando" ekhasini lasekhaya le-interface yokusebenza. |
Isifinyezo
Iphrotheni ebopha i-heparine iyi-molecule yephrotheni ekhishwa yi-granule ye-azurophilic ye-neutrophil esebenzayo.
i-granulin ebalulekile ekhishwa yi-neutrophil, ingavuselela i-monocyte kanye ne-macrophage, futhi inomphumela obalulekile
umsebenzi wokulwa namagciwane, izici ze-chemotactic kanye nomphumela wokulawulwa kwempendulo yokuvuvukala.
Ucwaningo lubonisa ukuthi iphrotheni ingaguqula namaseli e-endothelial, ibangele ukuvuza kwemithambo yegazi, futhi ikhuthaze ukufuduka
Amaseli amhlophe egazi aya endaweni yokutheleleka, futhi andise ukungena kwe-Vaso. Ngokusho kombiko wocwaningo, i-HBP ingaba khona
isetshenziselwa ukuxilongwa kwezifo ezisizayo, njengokwehluleka kokuphefumula nokujikeleza kwegazi, i-sepsis enzima, umgudu womchamo
ukutheleleka ezinganeni, ukutheleleka kwesikhumba okubangelwa amagciwane kanye ne-bacterial meningitis ebukhali.
Isici:
• Ukuzwela okuphezulu
• ukufundwa kwemiphumela ngemizuzu eyi-15
• Ukusebenza okulula
• Intengo eqondile yasefektri
• udinga umshini wokufunda imiphumela
