UKUSETSHENZISWA OKUHLOSIWE

I-Gastrin, eyaziwa nangokuthi i-pepsin, iyi-hormone yesisu ekhishwa kakhulu ngamaseli e-G e-gastric antrum kanye ne-duodenum futhi idlala indima ebalulekile ekulawuleni ukusebenza komgudu wokugaya ukudla kanye nokugcina isakhiwo esiphelele somgudu wokugaya ukudla. I-Gastrin ingakhuthaza ukukhishwa kwe-asidi yesisu, ikhuthaze ukukhula kwamaseli e-mucosal yesisu, futhi ithuthukise ukondleka kanye nokuhlinzekwa kwegazi kwe-mucosa. Emzimbeni womuntu, ngaphezu kwama-95% e-gastrin esebenzayo ngokwebhayoloji yi-α-amidated gastrin, equkethe ikakhulukazi ama-isomers amabili: i-G-17 kanye ne-G-34. I-G-17 ikhombisa okuqukethwe okuphezulu kakhulu emzimbeni womuntu (cishe ama-80% ~ 90%). Ukukhishwa kwe-G-17 kulawulwa ngokuqinile yinani le-pH le-gastric antrum futhi kubonisa indlela yokuphendula engemihle ehlobene ne-gastric acid.

Le khithi yenzelwe ukuthola inani le-Gastrin 17 (G-17) ku-serum/plasma/amasampula egazi lomuntu wonke. Le khithi inikeza kuphela umphumela wokuhlolwa kwe-Gastrin 17 (G-17).