umzimba: I-Sepsis, evame ukubizwa ngokuthi "umbulali othule," isifo esibucayi esiseyimbangela ehamba phambili yokufa okubangelwa ukutheleleka emhlabeni jikelele. Ngezibalo ezilinganiselwa ezigidini ezingama-20 kuya kwezingama-30 ze-sepsis unyaka ngamunye emhlabeni wonke, ukuphuthuma kokuhlonza nokwelapha i-sepsis kusenesikhathi kubaluleke kakhulu. Kuyisimo lapho umuntu elahlekelwa ukuphila kwakhe cishe njalo ngemva kwemizuzwana emi-3 kuya kwemi-4, okugqamisa isidingo esibalulekile sokungenelela ngokushesha.

I-AI engabonakaliiye yashintsha indlela i-sepsis exilongwa ngayo futhi zelashwa ngayo. Iphrotheni ebopha i-Heparin (i-HBP) iye yavela njengophawu olubalulekile lokutholwa kusenesikhathi kokutheleleka ngamagciwane, lisiza ochwepheshe bezempilo ekuboneni iziguli ze-sepsis ngokushesha. Lokhu kuthuthukiswa kuye kwathuthukisa kakhulu imiphumela yokwelashwa futhi kwanciphisa izehlakalo zezifo ezinzima zebhaktheriya kanye ne-sepsis.

I-AI engabonakaliidlala indima ebalulekile ekuhloleni ubunzima bokutheleleka ngokusekelwe ekugxilweni kwe-HBP. Uma amazinga e-HBP ephakama, yilapho ukutheleleka kunamandla kakhulu, kuhlinzeka ngemininingwane ebalulekile kubahlinzeki bezokunakekelwa kwempilo ukuze benze amasu okwelapha afanele. Ukwengeza, i-HBP isebenza njengethagethi yezidakamizwa ezihlukahlukene njenge-heparin, i-albumin, ne-simvastatin ukuze kubhekwane nokungasebenzi kahle kwezitho ngokunciphisa amazinga e-plasma e-HBP ngempumelelo.