Ukuhlolwa kwe-IgE okuphelele kuhlonza kanjani izinto ezibangela ukungezwani komzimba?

Ingabe uvame ukubhekana nokuqubuka okuphindaphindiwe, i-rhinitis, noma ukuphefumula ngokuzumayo? Lezi zinkinga zingase zikhombe emthonjeni ofanayo—ukungezwani komzimba. Imizimba yethu ine-"system yokuxilonga" eyinkimbinkimbi, futhiIngqikithi ye-IgEkuyingxenye ebalulekile. Ukuqondai-IgE iyonkeUkuhlolwa kungaba yisinyathelo sakho sokuqala ekuchazeni imfihlakalo yokungezwani komzimba.

KuyiniIngqikithi ye-IgE?

I-Immunoglobulin E (IgE) yi-antibody encane kakhulu ku-serum. Ukuhlushwa kwe-IgE ku-serum kungu-okuhambisana nobudala, kanti amanani aphansi kakhulu alinganiswa ekuzalweni. Ngokuvamile, amaqabunga e-lgE abantu abadalaitholwe ineminyaka engu-5 kuya kwengu-7 ubudala. Phakathi kweminyaka engu-10 nengu-14 ubudala, amazinga e-IgE angase abe phezulu kune-labo kubantu abadala. Ngemva kweminyaka engu-70, amazinga e-IgE angase ehle kancane futhi abe ngaphansi kwamazinga abonwe.kubantu abadala abangaphansi kweminyaka engama-40.
Kodwa-ke, izinga elijwayelekile le-IgE alikwazi ukuhlukanisa izifo zokungezwani komzimba. Ngakho-ke, ekuxilongweni okuhlukilengezifo zokungezwani komzimba kanye nezingezona ezokwaliwa, ukuhlonza inani le-IgE egazini lomuntu kuyasebenza kuphela.ukubaluleka lapho isetshenziswa kanye nezinye izivivinyo zemitholampilo.

Ingqikithi ye-IgEUkuhlolwa: "I-Navigator" Yokuxilonga Ukungezwani Nomzimba

I-IgE ephelele iyasebenza ekutholeni I-Immunoglobulin E ephelele (T-IgE)kumasampula egazi lomuntu/i-plasma/igazi eliphelele. Nakuba ingenakunquma ngokuqondile ukuthi iyiphi into ethile ebangela ukungezwani komzimba, ibaluleke kakhulu ekuxilongweni okusizayo kwezifo zokungezwani komzimba:

1. Ukuhlolwa okusizayo:Okuphakanyisiwei-IgE iyonkeIzinga lisikisela kakhulu ukuthi kukhona ukwakheka kwe-allergy noma ukutheleleka kwe-pathogen, okubonisa udokotela isiqondiso sokuhlolwa okwengeziwe.

2. Ukuhlolwa Kwengozi Nesivikeloy: Ngokuvamile, isilinganiso esiphezului-IgE iyonkeIzinga libonisa ukusabela okungathi sína kokungezwani komzimba, okusiza ekuhloleni ubukhali kanye nengozi yokuhlaselwa yizimo ezifana ne-asthma.

3. Ukuxilongwa Okuhlukile: Kuyasiza ukuhlukanisa phakathi kwezifo zokungezwani komzimba (njenge-rhinitis yokungezwani komzimba) kanye nezifo ezingezona ezokwaliwa yi-allergy (isb., i-vasomotor rhinitis).

4. Ukuqapha Ukusebenza Kokwelashwa: Ukuqapha njaloi-IgE iyonkeIzinguquko ngesikhathi sokwelashwa kokungazweli noma ukungenelela kwezidakamizwa zingahlola ngokungaqondile umphumela wokwelashwa.

Ubani Odinga Ukutholwa Kwe-Total IgE?

Kunconywa ukuthi abantu abanezimo ezilandelayo baxhumane nodokotela ukuze bathole ukuthi i-IgE iyonke tKunconywa ukuthi u-esting:

1. Izimpawu zokungezwani komzimba eziphinde zivele (i-eczema, i-urticaria/ama-hives, i-allergy rhinitis, i-asthma, njll.)

2. Umlando ocacile womndeni wokungezwani komzimba

3. Abantu abachayeke emsebenzini othile (isib. othulini, kumakhemikhali)

4. Ukuhlolwa kokuqala ngaphambi kokuqhubeka nokuhlolwa okuthile kwe-allergen

Kunconywa yi-Baysen Medical

Njengomkhiqizi ochwepheshe wama-reagent okuhlola ezokwelapha, i-We Baysen Medical izibophezele ekuhlinzekeni okunembile nokuthembekilei-IgE iyonke Ama-reagent e-Fia ane-Reader-I-Wiz-A101 futhiI-WIZ-A202,I-WIZ-A203, ukusiza izikhungo zezempilo ekuboneni izimpawu zokungezwani komzimba ngokushesha nangokunembile. Kodwa-ke, esifisa ukukugcizelela kakhulu ukuthi ukungezwani komzimba akuyona into engalawuleki. Ngokuhlolwa kwesayensi ukuze kucaciswe isimo somuntu, nangaphansi kwesiqondiso sikadokotela—ngokugwema ukuchayeka ku-allergen, ukuthola ukwelashwa okujwayelekile, noma ukwelashwa kokunciphisa ukusabela komzimba—izimpawu eziningi zokungezwani komzimba zingalawulwa ngempumelelo.