Iluphi Uhlobo Lwesitulo Olubonisa Umzimba Onempilo Kakhulu?

UMnu. Yang, owesilisa oneminyaka engu-45 ubudala, waya kodokotela ngenxa yohudo olungapheli, ubuhlungu besisu, nendle exutshwe namafinyila kanye nemivimbo yegazi. Udokotela wakhe uncome ukuhlolwa kwe-calprotectin ye-fecal, okuveze amazinga aphakeme kakhulu (>200 μg/g), okubonisa ukuvuvukala kwamathumbu. I-colonoscopy eyalandela yaqinisekisa ukutholakala kwe-ulcerative colitis engapheli.

Indle engavamile isebenza “njengesilinganiso” esibonakalayo sempilo yokugaya ukudla, enikeza izinkomba ezibalulekile zokutholwa kwezifo kusenesikhathi. Ukuhlonza okufika ngesikhathi kanye nokungenelela kungalawula ngokuphumelelayo ukuqhubeka kokuvuvukala futhi kunciphise ingozi yomdlavuza.

Imibandela Yokuhlola Yendle Enempilo

I-Bristol Stool Scale

I-Bristol Stool Classification System ihlukanisa i-stool morphology ngezinhlobo eziyisikhombisa, inikeza ukubonakaliswa okucacile kwesikhathi sokuhamba kwamathumbu nokusebenza kokugaya:

• Uhlobo 1-2:Indle eqinile, enezigaxa (ibonisa ukuqunjelwa).
• Uhlobo 3-4:Izihlalo ezibushelelezi, ezinjengesoseji (ezinhle, ifomu elinempilo).
• Uhlobo 5-7:Indle exegayo noma enamanzi (phakamisa isifo sohudo noma ukuhamba ngokushesha).

Umbala Wendle kanye Nemiphumela Yezempilo

Indle evamile ibonakala iphuzi ngokusagolide noma insundu ngenxa ye-bilirubin metabolism. Imibala engavamile ingase ibonise izinkinga eziyisisekelo:

• I-Black or Tarry Stools:
  • Izimbangela ezingezona eze-pathological: Izithako ze-iron, imithi ye-bismuth, noma ukusetshenziswa kwe-licorice emnyama.
  • Izimbangela ze-Pathological: Ukopha kwe-gastrointestinal ephezulu (isb., izilonda zesisu, umdlavuza wesisu). Indle emnyama ephikelelayo ehambisana nesiyezi noma i-anemia idinga ukunakekelwa kwezokwelapha ngokushesha.
• I-Red or Maroon Stools:
  • Izimbangela zokudla: Ama-beet noma isithelo sikadrako obomvu.
  • Izimbangela ze-Pathological: Ukopha okuphansi kwesisu (isb., ama-hemorrhoids, imifantu yendunu, umdlavuza we-colorectal).
• Izitulo Eziluhlaza:
  • Izimbangela ze-physiological: Ukudla kakhulu i-chlorophyll (isb, imifino enamaqabunga).
  • Izimbangela ze-Pathological: I-dysbiosis ye-gut (ukusetshenziswa kwangemuva kwemithi elwa namagciwane), isifo sohudo esithathelwanayo, noma ukuqhekeka kwe-bile okwanele.
• Indle Ephaphathekile noma Enombala Wobumba:
  • Khombisa ukuvinjelwa kwemigudu ye-bile, okungenzeka ngenxa ye-gallstones, i-hepatitis, noma umdlavuza we-pancreatic.

Ezinye Izinkomba Ze-morphological kanye Nezingozi Zezempilo

• Ezintantayo vs. Izitulo Ezicwilayo:
  • Ukuntanta: Ukudla okunefayibha ephezulu okubangela ukukhiqizwa kwegesi ngesikhathi sokuvutshelwa.
  • Ukucwila: Ukudla okuphezulu kwamaprotheni ezilwane, okungenzeka kuxhumene nengozi yomdlavuza we-colorectal.
• Okufana Netshe Elincane noma “Ubulongwe Bezimvu” (Indle Eyomile ku-TCM):
  • Phakamisa ukushoda kwe-Qi noma ukungalingani kwe-gut microbiota.
• Amafinyila noma Imivimbo Yegazi:
  • Ingase ibonise isifo samathumbu esivuthayo (IBD), ama-polyps amathumbu, noma i-enteritis ethathelwanayo.

Ithuluzi Lokuxilonga Elibalulekile: Inani Lomtholampilo Le-FecalUkuhlolwa kweCalprotectin

I-Calprotectiniphrotheni ekhombisa umsebenzi we-neutrophil emathunjini. Ukuhlolwa kwayo kunikeza izinzuzo ezibalulekile:

1. Ukuhlola Okungahlaseli:
   • Ihlola ukuvuvukala kwamathumbu ngamasampula endle, isiza ekuxilongweni kwe-IBD, i-adenomas, noma umdlavuza we-colorectal ngaphandle kwezinqubo zokuqala zokuhlasela njenge-colonoscopy.
2. Ukuxilongwa Okuhlukile:
   • Isiza ukuhlukanisa phakathi kwe-inflammatory bowel syndrome (IBD) kanye nesifo samathumbu esicasulayo (IBS).
3. Ukuqapha Ukwelashwa:
   • Ukulandelelai-calprotectinamazinga ahlola ngokuguquguqukayo ukusebenza kwemithi kanye nengozi yokuphindela ekuguleni.