KA HOʻOHANA I MANAʻO ʻIA

ʻO Gastrin, i ʻike ʻia hoʻi ʻo pepsin, he hormone gastrointestinal i hūnā nui ʻia e nā cell G o ka gastric antrum a me duodenum a he kuleana koʻikoʻi kāna i ka hoʻoponopono ʻana i ka hana o ke ala ʻai a me ka mālama ʻana i ke ʻano paʻa o ke ala ʻai. Hiki iā Gastrin ke hoʻolaha i ka huna ʻana o ka waikawa gastric, hoʻomaʻamaʻa i ka ulu ʻana o nā cell mucosal gastrointestinal, a hoʻomaikaʻi i ka meaʻai a me ka lako koko o ka mucosa. I loko o ke kino kanaka, ʻoi aku ma mua o 95% o ka gastrin biologically active he α-amidated gastrin, nona nā isomers ʻelua: G-17 a me G-34. Hōʻike ʻo G-17 i ka ʻike kiʻekiʻe loa i loko o ke kino kanaka (ma kahi o 80% ~ 90%). Hoʻomalu pono ʻia ka huna ʻana o G-17 e ka waiwai pH o ka gastric antrum a hōʻike i ka ʻano pane maikaʻi ʻole e pili ana i ka waikawa gastric.

Ua manaʻo ʻia kēia pahu no ka ʻike ʻana i ka nui o Gastrin 17 (G-17) i loko o nā hāpana serum/plasma/koko holoʻokoʻa kanaka. Hāʻawi wale kēia pahu i ka hopena hoʻāʻo o Gastrin 17 (G-17).