Imeghe dashboard ọrịa shuga: nghọtaHbA1c, Insulin, naC-Peptide

Na mgbochi, nchoputa, na njikwa nke ọrịa shuga, ọtụtụ isi ihe na-egosi na akụkọ ụlọ nyocha dị oke mkpa. Na mgbakwunye na nke a maara nke ọma glucose ọbara na-ebu ọnụ na glucose ọbara postprandial,HbA1c, insulin, na C-peptidena-arụkwa ọrụ ndị dị mkpa. Ha na-eme ihe dị ka ndị nchọpụta atọ, nke ọ bụla nwere nka nke ya, na-ekpughe eziokwu gbasara etu anụ ahụ si ahazi glucose ọbara n'ụdị dị iche iche.

1.Glycosylated haemoglobin A1c (HbA1c): "Onye na-edekọ ogologo oge" nke glucose ọbara

Ị nwere ike iche maka ya dị ka "kaadị mkpesa shuga dị n'ọbara" n'ime ọnwa 2-3 gara aga. Hemoglobin dị n'ọbara ọbara gị na-ejikọta ya na glucose n'ọbara - usoro a na-akpọ glycation. Ka ọ̀tụ̀tụ̀ shuga dị n'ọbara na-abawanye, otú ahụ ka ọ̀tụ̀tụ̀ glycation na-abawanye.

Isi ọrụ ya bụ:

• Nyochaa njikwa glucose ọbara ogologo oge: n'adịghị ka mmụgharị nwa oge na ọkwa glucose ọbara,HbA1cna-egosipụta nke ọma nkezi ọkwa glucose ọbara n'ime izu 8-12 gara aga ma bụrụ ọkọlọtọ ọla edo maka nyocha ịdị irè nke usoro ọgwụgwọ ọrịa shuga.
• Ịnye aka na nchọpụta ọrịa shuga: Dị ka ụkpụrụ WHO si kwuo, an HbA1cEnwere ike iji ọkwa ≥ 6.5% mee ihe dị ka otu ụkpụrụ maka ịchọpụta ọrịa shuga.

Na nkenke, ọ bụrụ na ibu ọnụ na mgbe nri gasịrị, glucose ọbara bụ “nyocha” nke obere oge,HbA1cbụ “akwụkwọ,” na-egosi nkọwa zuru oke nke njikwa glucose ogologo oge gị.

2. Insulin na C-Peptide: Onye mmekọ ọla edo nke ọrụ Pancreatic

Iji ghọta ihe na-akpata okwu shuga n'ọbara, anyị ga-eleba anya na isi mmalite - ọrụ nke mkpụrụ ndụ beta nke pancreatic. Nke a bụ ebe “ụmụnne ejima,”InsulinnaC-Peptide, Bata.

• Insulin: Ezobere ya site na mkpụrụ ndụ beta nke pancreatic, ọ bụ naanị homonụ na-ebelata shuga ọbara. Ọ na-eme dị ka “igodo,” imeghe ọnụ ụzọ cell na ikwe ka shuga banye n'ọbara ma mee ka ọ bụrụ ike.
• C-Peptide: Nke a bụ ihe emepụtara n'otu oge yana nha nha yana insulin site na mkpụrụ ndụ beta. Ọ nweghị ọrụ ọ bụla n'ibelata shuga ọbara n'onwe ya, mana ọ bụ "ịgba akaebe kwesịrị ntụkwasị obi" nyeinsulinmmepụta.

Yabụ, kedu ihe kpatara nwalee ha abụọ n'otu oge?

Isi uru bụ nke ahụ C-peptidekwụsiri ike ma nwee ogologo ndụ ọkara karịa insulin, na-enye ya ohere igosipụta nke ọma ọrụ nzuzo nke mkpụrụ ndụ β-pancreatic. N'ime ndị ọrịa nwere ọrịa shuga na-enwetala ọgwụgwọ insulin exogenous, ọgwụ mgbochi insulin nwere ike ịmalite, na-egbochi izi ezi nke nnwale insulin.C-peptide, Otú ọ dị, nke a emetụtaghị ya, si otú a na-aghọ ihe ngosi a pụrụ ịdabere na ya maka ịlele ikike nzuzo insulin nke onye ọrịa.

3. The Trio in Concert: Foto zuru oke

Na omume ụlọ ọgwụ, ndị dọkịta na-ejikọta ihe atọ ndị a iji mepụta profaịlụ metabolic doro anya:

1. Ịmata Ụdị Ọrịa shuga:

• Maka onye ọrịa achọpụtara na-arịa ọrịa shuga, dị oke alainsulinnaC-peptideỌkwa a na-egosi ụkọ siri ike na mmepụta insulin, ikekwe na-ekewa ya dị ka ụdị ọrịa shuga 1.
• If insulin na C-peptideỌkwa dị mma ma ọ bụ ọbụna dị elu, mana shuga ọbara ka dị elu, ọ na-egosi nguzogide insulin, njirimara nke ụdị ọrịa shuga 2.

2. Nyochaa Ọrụ Pancreatic & InsulinNguzogide:

• Nke insulin / C-peptide Nnwale ntọhapụ” na-ahụ mgbanwe dị egwu nke ihe ngosi ndị a mgbe ha richara mmanya na-egbu egbu, nke nwere ike inye aka chọpụta nchekwa na ikike nzuzo nke mkpụrụ ndụ β-pancreatic.
• Elu insulinna elu C-peptideọkwa shuga dị n'ọbara na-esonyere ya bụ ihe akaebe nke nguzogide insulin.

3. Atụmatụ ọgwụgwọ na-eduzi:

• Maka ndị ọrịa mamịrị 2dị nke abụọ nwere ọrụ pancreatic echekwara echekwabara, ọgwụ ndị na-eme ka nguzogide insulin nwere ike bụrụ nhọrọ mbụ.
• Maka ndị ọrịa nwere ọrụ pancreatic ọ fọrọ nke nta ka ike gwụ, ọ dị mkpa ịmalite ọgwụgwọ insulin n'oge.

Nchịkọta

• HbA1c na-egosipụta "nsonaazụ" nke njikwa shuga ọbara dị ogologo oge
• InsulinnaC-Peptidegosi “ikike” na “arụmọrụ” nke usoro njikwa shuga dị n'ime ahụ gị.
• Ọbara glucose na-egosi “ọnọdụ” ahụ gị ugbu a.

Ịghọta ihe nrịbama atọ a pụtara na-enye ohere maka nghọta miri emi banyere ọrịa shuga. Ọ na-enye gị ike ka gị na dọkịta gị nwee mkparịta ụka nke ọma ma rụkọọ ọrụ ọnụ iji mepụta nleba anya na atụmatụ ọgwụgwọ ahaziri maka nkenke, njikwa ahụike sayensị.

Mmechi

Anyị Baysen Medical na-elekwasị anya mgbe niile na usoro nyocha iji melite ogo ndụ. Anyị mepụtara nyiwe teknụzụ 5- Latex, ọla edo colloidal, Fluorescence Immunochromatographic Assay, Molecular, Chemiluminescence Immunoassay, AnyịNgwa nyocha HbA1c,Ngwa nyocha insulin ,Ngwa ule C-peptideọrụ dị mfe ma nwee ike nweta nsonaazụ ule na nkeji iri na ise