Ko te Interleukin-6 he polypeptide e rua ngā mekameka glycoprotein, ko te taumaha ngota o te 130kd. Hei mema nui o te whatunga cytokine, he mahi nui tā te interleukin-6 (IL-6) i roto i te tauhohenga mumura tere, ā, ka taea e ia te whakahaere i te tauhohenga wāhanga tere o te ate, me te whakaoho i te whakaputanga o te pūmua C-reactive (CRP) me te fibrinogen. He maha ngā mate pāwera ka arahi pea ki te pikinga o te taumata IL-6 i roto i te toto, ā, he hononga tata te taumata IL-6 ki ngā putanga o te tūroro. Hei cytokine pleiotropic me ngā mahi whānui, ka tukuna te IL-6 e te pūtau T, te pūtau B, te mononuclear phagocyte, me te pūtau endothelial, ā, he wāhanga matua o te whatunga takawaenga mumura. I te putanga mai o te tauhohenga mumura, ka puta tuatahi ngā IL-6, ka whakaoho i te whakaputanga o te CRP me te procalcitonin (PCT) i te wā e puta ai. Ka tere te whakaputanga mēnā ka pāngia koe e te mate, ngā whara o roto me waho, te pokanga, te tauhohenga ahotea, te mate roro, te mate pukupuku, me te tukanga tauhohenga mumura tere o ētahi atu āhuatanga. Kei roto te IL-6 i te putanga mai me te whanaketanga o ngā mate maha, he hononga tata tōna taumata toto ki te mumura, te mate huaketo me te mate pūnaha ārai mate, ā, ka puta wawe ōna huringa i te CRP. E ai ki ngā hua rangahau, ka tere te piki o te taumata IL-6 i te pangia e te kitakita, ka piki te taumata PCT i muri i te 2 hāora, ko te CRP ia ka tere te piki i muri i te 6 hāora. Ko te whakaputanga rerekē, te whakaaturanga ira rānei o te IL-6 ka arahi pea ki te putanga mai o ngā mate maha, ka taea te whakaputa i te nui o te IL-6 ki roto i te rere toto i roto i te āhua mate, ā, he mea tino nui te kitenga o te IL-6 ki te tautuhi mate me te whakatau matapae.