Ko te Cardiac Troponin T (cTnT), he wāhanga iti o te matatini troponin e whakaatuhia motuhake ana i roto i ngā pūtau ngākau, ko tētahi o ngā tohu koiora tino nui, tino nui hoki i roto i te rongoā pūnaha ngākau hou. Ko tōna hiranga kei roto i tōna tino motuhaketanga ki te ngākau, te tino aro, me tōna tūranga matua i roto i te tautuhi, te wehewehe mōrearea, me te whakahaere i ngā mate pūkahukahu whakapeka (ACS) me ētahi atu whara o te ngākau.

Ko te mea nui, ko te cTnT te tohu matua mō te tautuhi i te mate ngakau (MI). I mua i te whakamahinga o te troponin, i whakawhirinaki ngā tautuhi ki ngā tohu iti ake te motuhake pērā i te Creatine Kinase-MB (CK-MB) me ngā tohu haumanu, ka hua ake te koretake o te tautuhi. Ko te tukunga o te cTnT ki roto i te toto i muri i te mate ngakau he tino motuhake ki te kino o te uaua o te ngakau. Nā te taenga mai o ngā whakamātautau troponin T teitei-aro (hs-cTnT) kua huri i tēnei mara. Ka taea e ēnei whakamātautau te kite i ngā pikinga iti o te cTnT i raro iho i te rohe tohutoro o runga 99 o te taupori noa. Mā tēnei ka taea e ngā tākuta te tautuhi i te whara o te ngakau i mua atu - i roto i te 1-3 haora o te whakaaturanga o te tari urupare ohorere - ka taea ai te whakatau tere ake, me te mea nui, te whakatau tere ake me te maia o te MI. Mā tēnei ka tere ake te maimoatanga mō ngā tūroro pono, ā, ka tukuna haumaru ngā tūroro iti te mōrearea, ka whakapai ake i te whai huatanga o te tari urupare ohorere me te rere o te tūroro.

Haunga ngā tātaritanga, he mahi nui tā te cTnT i roto i te wehewehenga mōrearea me te matapae. He hononga kaha te nui o te pikinga o te cTnT ki te whānuitanga o te kino o te uaua ngākau, ā, he tohu motuhake kaha mō ngā hua kino mō te wā poto me te wā roa, tae atu ki te ngoikore o te ngakau, te mate urutā auau, me te mate. Ahakoa ngā pikinga iti, mau tonu i kitea e ngā whakamātautau hs-cTnT i roto i ngā tūroro āhua pumau ka taea te tautuhi i te hunga he whara uaua ngākau iti, e tohu ana i te nui ake o te mōrearea o ngā mate cardiovascular a meake nei. Nā tēnei ka waiho te cTnT hei taputapu whai hua ehara i te mea i roto i ngā horopaki ohorere anake engari i roto hoki i te whakahaere i ngā āhuatanga mau tonu pēnei i te mate uaua ngākau pumau, te ngoikore o te ngakau, me te mate tākihi mau tonu.

Hei tāpiri atu, ko te ine i te cTnT te arataki i ngā whakataunga rongoā nui. He mea nui te pikinga me te hekenga rānei o te tauira cTnT hei tautuhi i te MI whakapeka e ai ki ngā aratohu whānui. Mā tēnei whakaū matū koiora ka whakamōhio tika i ngā wawaotanga tere pēnei i te angiography coronary me te revascularization (PCI, CABG rānei). Ka āwhina hoki i te whiriwhiri me te aroturuki i te whai huatanga o ngā maimoatanga rongoā, tae atu ki ngā kaihoko antiplatelet kaha (hei tauira, ticagrelor, prasugrel) me ngā rongoā anticoagulant.

Ka horapa te hiranga o te cTnT ki ngā āhuatanga o te ngākau kāore i te ischemic. Ka kitea ngā taumata teitei i roto i ngā mate maha e puta ai te taumahatanga, te whara rānei o te uaua o te ngākau, pērā i te myocarditis, te whara o te ngākau, te sepsis nui, te pulmonary embolism e puta ai te taumahatanga o te ngākau matau, me te paitini o te ngākau e pā ana ki te chemotherapy. I roto i ēnei horopaki, he tohu tairongo te cTnT mō te whai wāhi o te ngākau, e akiaki ana i te rangahau me te whakahaere i ngā mea kua whakaritea.

Hei whakamutunga, kua tino hurihia e te Cardiac Troponin T te mahi tirotiro ngakau. Nā tōna whanaketanga ki tētahi whakamātautau tairongo-teitei kua whakaū i tōna tūnga hei tohu koiora matua mō te whara o te uaua ngākau. Mā te whakarato i te tika o te tātaritanga, ngā mōhiohio matapae kaha, me ngā aratohu nui mō ngā maimoatanga whakaora ora, he mea nui te cTnT mō te whakapai ake i ngā putanga o ngā tūroro i roto i ngā āhuatanga ohorere o te ngakau me te whakahaere roa o te mate ngakau. Ko tōna ine he paerewa kore e taea te whiriwhiri i roto i te tiaki ngakau o nāianei.