The World Health Organization estimates that tens of millions of people worldwide suffer from diarrhoea every day and that there are 1.7 billion cases of diarrhoea each year, with 2.2 million deaths due to severe diarrhoea. And CD and UC, easy to repeat, difficult to cure, but also secondary gastrointestinal infection, tumor and other complications. Otherwise Colorectal cancer has the third highest incidence and second highest mortality worldwide.
Calprotectin, It is a calcium-zinc binding protein secreted by neutrophils, is a marker of intestinal inflammation. It is so stable and it is the Markers of intestinal inflammation and affected by the “severity of intestinal inflammation. Otherwise Cal has high specificity in diagnosing intestinal inflammation.
Detection of hemoglobin in faeces can effectively assess the risk of intestinal bleeding, but It is easily digested and hydrolyzed by digestive enzymes and bacteria, which makes it difficult to detect a small amount of bleeding in feces. But The diagnosis of intestinal bleeding is highly specific.
So Combination of FOB and Cal has a better diagnostic accuracy performance compared to each test alone for the detection of relevant colonic pathology in symptomatic patients. Performing FOB and FC before colonoscopy is a cost-effective strategy in order to avoid unnecessary procedures and complications.
We had developing the Diagnostic Kit for Calprotectin/Fecal Occult Blood , The detection cost for cal and fob combo is so low, and it is more suitable for intestinal disease screening.
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Post time: Apr-11-2023