Pepsinogen IAna haɗa shi kuma ana fitar da shi ta manyan ƙwayoyin halitta na yankin glandular oxyntic na ciki, kuma yankin pyloric na ciki ana haɗa shi kuma ana fitar da pepsinogen II. Dukansu suna kunna zuwa pepsins a cikin lumen na ciki ta hanyar HCl da ƙwayoyin fundic parietal ke fitarwa.

1. Menene pepsinogen II?
Pepsinogen II yana ɗaya daga cikin furotin aspartic guda huɗu: PG I, PG II, Cathepsin E da D. Ana samar da Pepsinogen II galibi a cikin mucosa na glandar Oxyntic na ciki, antrum na ciki da duodenum. Ana fitar da shi galibi cikin lumen na ciki da kuma cikin zagayawar jini.
2. Menene sinadaran pepsinogen?
Pepsinogens sun ƙunshi sarkar polypeptide guda ɗaya mai nauyin kwayoyin halitta kimanin Da 42,000. Ana haɗa Pepsinogens kuma ana fitar da su galibi ta manyan ƙwayoyin ciki na cikin ɗan adam kafin a canza su zuwa pepsin, wanda yake da mahimmanci ga tsarin narkewar abinci a cikin ciki.
3. Menene bambanci tsakanin pepsin da pepsinogen?
Pepsin wani enzyme ne na ciki wanda ke aiki don narkar da sunadaran da ake samu a cikin abincin da aka ci. Manyan ƙwayoyin ciki suna fitar da pepsin a matsayin zymogen mara aiki da ake kira pepsinogen. Kwayoyin parietal a cikin rufin ciki suna fitar da hydrochloric acid wanda ke rage pH na ciki.

Kayan Bincike don Pepsinogen I/ PepsinogenII (Fluorescence Immuno Assay)Gwajin haske ne na immunochromatographic don gano PGI/PGII a cikin jini ko plasma na ɗan adam, galibi ana amfani da shi don tantance aikin ƙwayoyin oxyntic na ciki da cutar glandar mucinous na ciki a asibiti.

Barka da zuwa tuntuɓar mu don ƙarin bayani.