He aha ka Calprotectin?

He protein ʻo Calprotectin i loaʻa maoli i loko o kou kino, ʻoi aku hoʻi i loko o kahi ʻano o ke koko keʻokeʻo i kapa ʻia he neutrophil. ʻO kēia mau cell kekahi ʻāpana o kāu ʻōnaehana pale a holo wikiwiki i nā wahi o ka mumū a i ʻole ka maʻi. Ke loaʻa ka mumū i loko o nā ʻōpū, lilo kēia mau neutrophils i mea hana a hoʻokuʻu i ka calprotectin. No laila, pili pono ka pae o ka calprotectin i loko o kahi hāpana ʻōpala me ka nui o ka mumū i loko o ke ala gastrointestinal (GI).

No ke aha i hana ʻia ai ka hoʻāʻo?

ʻO ke kumu nui no ka hoʻāʻo calprotectin ʻo ia ke kōkua i nā kauka e hoʻokaʻawale ma waena o ʻelua mau ʻano nui o nā pilikia o ka ʻōpū:

1. Ka Maʻi ʻŌpū Mumū (IBD): Hoʻokomo pū kēia me nā kūlana e like me ka maʻi a Crohn a me ka colitis ulcerative, kahi e hoʻouka hewa ai ka ʻōnaehana pale i ka uhi o ke ala GI, e hoʻoulu ai i ka mumū mau loa.
2. ʻO ka maʻi ʻōpū huhū (IBS): He maʻi hana kēia kahi e palupalu ai ka ʻōpū a hoʻoulu i nā hōʻailona e like me ka ʻūlū a me ka pehu ʻana, akā ʻaʻohe mumū a hōʻino paha i ʻike ʻia.

Hiki ke like loa nā hōʻailona o IBD a me IBS—e like me ka ʻeha o ka ʻōpū, ka maʻi palahēhē mau, a me ka pehu ʻana. Hana ka hoʻāʻo calprotectin ma ke ʻano he "hōʻailona mumū" kōkua e kuhikuhi i nā kauka i ke ala kūpono.

Pehea e hana ʻia ai ka hoʻāʻo?

He mea maʻalahi loa ka hoʻāʻo ʻana a ʻaʻole ia e komo i loko o ka ʻōpū. Pono wale ia i kahi hāpana ʻuʻuku o ka ʻōpala, kahi āu e hōʻiliʻili ai ma ka home me ka hoʻohana ʻana i kahi pahu kūikawā i hāʻawi ʻia e kāu kauka a i ʻole ke keʻena lapaʻau. A laila hoʻouna ʻia ka hāpana i kahi keʻena hoʻokolohua no ka nānā ʻana. Ma laila, ana nā loea i ka nui o ka calprotectin i loko o ka ʻōpala, i hōʻike pinepine ʻia ma nā micrograms no ka gram (µg/g).

He aha ke ʻano o nā hopena?

Pae Maʻamau/Haʻahaʻa: ʻO kahi hopena i loko o ka pae maʻamau (pinepine ma lalo o 50 µg/g, akā hiki ke ʻokoʻa ka paepae pololei ma muli o ka lab) hōʻike ikaika ʻaʻole paha ka mumū ikaika i loko o nā ʻōpū. Kākoʻo kēia i kahi hōʻailona o kahi maʻi ʻaʻole mumū e like me IBS.
Pae Kiʻekiʻe: ʻO ka pae calprotectin kiʻekiʻe e hōʻike ana aia ka mumū ma ke ala GI. Pono kēia i ka noiʻi hou aku e hoʻoholo i ke kumu. ʻOiai he hōʻailona ikaika ia no ka IBD, hiki ke loaʻa nā pae kiʻekiʻe i nā kūlana ʻē aʻe e like me nā maʻi bacteria, colitis, a i ʻole ke kanesa colon. No laila, ʻaʻole ia he mea hana hōʻoia hope loa no kahi maʻi kikoʻī akā he alakaʻi koʻikoʻi.
No nā kānaka me ka IBD i ʻike ʻia: Hoʻohana ʻia ka hoʻāʻo e nānā i nā poʻe maʻi i ʻike mua ʻia me Crohn's a i ʻole colitis. ʻO ka nānā mau ʻana i nā pae calprotectin e kōkua i nā kauka e loiloi inā e hana ana ka lāʻau lapaʻau, inā e hoʻomaha ana ka maʻi, a inā paha e hoʻomaka ana kahi flare-up, i kekahi manawa ma mua o ka ʻike ʻia ʻana o nā hōʻailona.

Nā Pōmaikaʻi a me nā Palena

Nā Pōmaikaʻi:
ʻAʻole komo kino: ʻAʻohe nila a i ʻole nā ​​​​​​mea ʻike maka e pono ai no ka nānā mua ʻana.
Mea Hana Triage Kōkua: Kōkua pono i ka hoʻokaʻawale ʻana i nā kūlana mumū mai nā kūlana ʻaʻole mumū, e hōʻemi ana i ka pono no nā kaʻina hana invasive pono ʻole e like me ka colonoscopies no nā maʻi IBS.
Maikaʻi no ka Nānā ʻana: Hāʻawi i kahi ana kūʻokoʻa o ka mumū i ka hala ʻana o ka manawa.

Nā Palena:
ʻAʻole Kikoʻī: Kuhikuhi ia i ka mumū akā ʻaʻole ʻike i kona kumu a i ʻole kona wahi.
Hiki ke loaʻa nā hopena wahaheʻe: Hiki ke ʻike ʻia nā pae kiʻekiʻe me ka hoʻohana ʻana i ka NSAID, kekahi mau maʻi ʻōpū, a i ʻole i ka poʻe ʻelemakule.
Pono e Hahai: ʻO ka hopena maikaʻi e pono mau ai ka hoʻokolokolo hou ʻana, ma ke ʻano maʻamau me nā kaʻina hana endoscopic e like me ka colonoscopy e loaʻa ai kahi hōʻailona ʻike maka a lawe i nā biopsies.

Hopena

I ka hōʻuluʻulu manaʻo, he mea waiwai nui ka hoʻāʻo calprotectin fecal a he mea hana maʻalahi hoʻi no ka mea maʻi i ka gastroenterology hou. He mea ia e nānā mua ai i ka mumū o ka ʻōpū, e kōkua ana i ka hoʻokaʻawale ʻana ma waena o IBD a me IBS a me ke alakaʻi ʻana i nā hoʻoholo e pili ana i ka pono o nā hoʻāʻo invasive hou aku. Inā ʻoe e ʻike nei i nā hōʻailona digestive mau, e kamaʻilio me kāu kauka e pili ana inā paha he hana mua pono ka hoʻāʻo calprotectin i kāu huakaʻi diagnostic.

Hiki iā mākou ke hoʻolako i ka hoʻāʻo wikiwiki ʻo Baysenhoʻāʻo wikiwiki calprotectinpahu inā ʻoe e nele. Welina e hoʻokaʻaʻike mai iā mākou inā he hoihoi kāu.