Kev txiav txim siab meej ntawmFolateQhov Tseeb: Txij li "Yuav Tsum Noj Ntau Npaum Li Cas" mus rau "Siv Tau Zoo"

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Folate—uas yog lub hauv paus ntawm kev yug menyuam noj qab nyob zoo—yog qhov paub rau yuav luag txhua tus khub niam txiv uas npaj cev xeeb tub thiab cov neeg uas nyob rau lub sijhawm perinatal. Txawm li cas los xij, qhov tseeb uas tau saib tsis taus ntev tseem nyob: kev vam meej ntawm kev noj folate ntxiv tsis yog nyob ntawm "koj noj ntau npaum li cas," tab sis ntawm koj lub cev "siv ntau npaum li cas."

Kev xav ib txwm feem ntau tsuas yog tsom mus rau qhov kev ua ntawm kev noj tshuaj ntxiv thaum tsis quav ntsej txog ob yam tseem ceeb: thawj, seb lub cev cov folate tam sim no puas txaus, thiab qhov thib ob, seb lub cev puas tuaj yeem hloov pauv thiab siv nws tau zoo. Hauv kev txiav txim siab hauv kev kho mob, cov kws kho mob xav tau kev nkag siab txog tus neeg mob cov zaub mov tam sim no rau kev cuam tshuam tam sim ntawd thiab kev ntsuam xyuas lawv lub peev xwm metabolic los tsim cov tswv yim mus sij hawm ntev.

Yuav kom daws tau qhov teeb meem no, yuav tsum muaj cov cuab yeej kuaj mob kom meej dua. Peb cov kev daws teeb meem kuaj folate tau tsim tshwj xeeb rau lub hom phiaj no:

Kauj Ruam 1: Txheeb xyuas "Cov Qib Tam Sim No" nrogWIZ-A101thiabWIZ-A203

Cov tshuaj folate hauv cov ntshav yog qhov qhia tseem ceeb uas qhia txog lub cev cov folate tam sim no, txuas ncaj qha rau kev loj hlob ntawm lub raj xa dej ntawm tus menyuam hauv plab. Peb cov tshuaj fluorescent immunoassay serum folate detection reagent, siv ua ke nrog WIZ-A101tag nrho cov qauv pretreatment system thiabWIZ-A203fluorescence immunoassay analyzer, ua rau muaj kev ntsuas ntau ntawm cov folate hauv cov ntshav.WIZ-A101 ua kom cov qauv ua ntej thiab kev npaj cov tshuaj tiv thaiv ua haujlwm tau zoo, thaum lub sijhawm ntawdWIZ-A203ntes thiab tshuaj xyuas cov teeb liab fluorescence kom raug qhov tseeb tso tawm cov nqi folate concentration hauv cov ntshav, muab cov ntaub ntawv ntsuam xyuas kev noj haus rau cov kws kho mob lub sijhawm tiag tiag.

Kauj Ruam 2: Kev Kuaj Genetic kom Qhib "Lub Peev Xwm Nqus Tau"

Yog tias MTHFR gene nqa cov kev hloov pauv (xws li ntawm C677T locus), cov haujlwm ntawm cov enzymes tseem ceeb hauv folate metabolism tuaj yeem txo qis heev, nrog rau kev siv cov folic acid ib txwm poob qis mus rau qis li 30% ntawm cov qib ib txwm. Ua ke nrog folate metabolic peev xwm caj ces,cov noob caj noob ces ntawm ib tus neeg tuaj yeem txheeb xyuas tau meej, faib cov neeg mob ua pawg qis, nruab nrab, lossis muaj kev pheej hmoo siab, yog li zam qhov teeb meem ntawm "kev noj tshuaj tsis zoo" lossis "kev noj tshuaj ntau dhau."

Ib Txoj Kev Tswj Xyuas Peb Kauj Ruam Uas Kaw: Kev Ntsuas (WIZ-A101kev kho mob ua ntej +WIZ-A203Kev kuaj pom ntau ntawm cov fluorescence kom tau txais cov nqi folate hauv cov ntshav, ua ke nrog genotyping) → Kev Ntsuas (cov qib tam sim no + lub peev xwm metabolic) → Kev Pabcuam Tus Kheej (kev qhia txog kev noj tshuaj thiab kev xaiv cov mis). Qhov no yog qhov hloov pauv ntawm kev noj tshuaj folate los ntawm kev xyaum "empirical" mus rau lub sijhawm ntawm "kev kho mob meej."Folate kev noj ntxiv yeej tsis yog kev sib tw ntawm "ntau npaum li cas," tab sis yog ib qho tswv yim uas tsom mus rau "kev ua haujlwm tau zoo."