Kodi Calprotectin ndi chiyani?

Calprotectin ndi puloteni yomwe imapezeka mwachibadwa m'thupi lanu, makamaka mkati mwa mtundu wa selo loyera la magazi lotchedwa neutrophil. Maselo amenewa ndi mbali ya chitetezo chanu cha mthupi ndipo amathamangira kumadera omwe muli kutupa kapena matenda. Pakakhala kutupa m'matumbo, ma neutrophil amenewa amayamba kugwira ntchito ndipo amatulutsa calprotectin. Chifukwa chake, kuchuluka kwa calprotectin mu ndowe kumagwirizana mwachindunji ndi kuchuluka kwa kutupa m'mimba (GI).

N’chifukwa chiyani mayesowa amachitika?

Chifukwa chachikulu choyesera calprotectin ndikuthandiza madokotala kusiyanitsa mitundu iwiri ikuluikulu ya mavuto a m'mimba:

1. Matenda a m'mimba otupa (IBD): Izi zikuphatikizapo matenda monga matenda a Crohn ndi matenda a zilonda zam'mimba, komwe chitetezo cha mthupi chimaukira molakwika mkati mwa thirakiti la m'mimba, zomwe zimayambitsa kutupa kosatha.
2. Matenda a m'mimba okwiya (IBS): Uwu ndi matenda omwe amachititsa kuti m'mimba mukhale omasuka komanso amachititsa zizindikiro monga kupweteka m'mimba ndi kutupa, koma palibe kutupa kapena kuwonongeka komwe kumawonekera.

Zizindikiro za IBD ndi IBS—monga kupweteka m'mimba, kutsegula m'mimba kosalekeza, ndi kudzimbidwa—zingakhale zofanana kwambiri. Mayeso a calprotectin amagwira ntchito ngati "chizindikiro chotupa" chothandiza kutsogolera madokotala njira yoyenera.

Kodi Mayeso Amachitidwa Bwanji?

Kuyesaku ndi kosavuta komanso kosavulaza. Kumafuna chitsanzo chaching'ono cha ndowe, chomwe mumachisonkhanitsa kunyumba pogwiritsa ntchito zida zapadera zomwe dokotala wanu kapena chipatala chanu amapereka. Kenako chitsanzocho chimatumizidwa ku labotale kuti chiwunikidwe. Kumeneko, akatswiri amayesa kuchuluka kwa calprotectin mu ndowe, zomwe nthawi zambiri zimanenedwa mu ma microgram pa gramu (µg/g).

Kodi Zotsatira zake Zimatanthauza Chiyani?

Mlingo Wabwinobwino/Wotsika: Zotsatira zomwe zili mkati mwa mulingo wabwinobwino (nthawi zambiri pansi pa 50 µg/g, koma mulingo weniweni ukhoza kusiyana malinga ndi labu) zikusonyeza kuti kutupa kwa matumbo sikungatheke. Izi zikuthandizira kuzindikira matenda osatupa monga IBS.
Mulingo Wapamwamba: Kuchuluka kwa calprotectin kumasonyeza kuti kutupa kuli mu GI tract. Izi zikufunika kufufuza kwina kuti mudziwe chomwe chimayambitsa. Ngakhale kuti ndi chizindikiro champhamvu cha IBD, kuchuluka kwa milingo kumatha kuchitikanso m'matenda ena monga matenda a bakiteriya, colitis, kapena khansa ya m'matumbo. Chifukwa chake, si chida chodziwira matenda enaake koma chitsogozo chofunikira.
Kwa Anthu Odziwika ndi IBD: Mayesowa amagwiritsidwanso ntchito poyang'anira odwala omwe apezeka kale ndi matenda a Crohn's kapena colitis. Kuyang'ana kuchuluka kwa calprotectin nthawi zonse kumathandiza madokotala kuona ngati chithandizo chikugwira ntchito, ngati matendawa akuchira, kapena ngati kuphulika kwayamba, nthawi zina ngakhale zizindikiro zisanawonekere.

Ubwino ndi Zofooka

Ubwino:
Sizowononga: Sipafunika singano kapena ma scope poyesa koyamba.
Chida Chothandiza Chothandizira Kuchotsa Matenda: Chimathandiza bwino kusiyanitsa matenda otupa ndi omwe si otupa, kuchepetsa kufunikira kwa njira zosafunikira monga colonoscopy kwa odwala a IBS.
Zabwino Poyang'anira: Zimapereka muyeso weniweni wa kutupa pakapita nthawi.

Zoletsa:
Sizikutanthauza: Zimazindikira kutupa koma sizimadziwa chomwe chimayambitsa kapena komwe kuli.
Zingakhale ndi Zotsatira Zabodza: ​​Kuchuluka kwa milingo kumatha kuoneka pogwiritsa ntchito NSAID, matenda ena am'mimba, kapena okalamba.
Kutsatira Kofunikira: Zotsatira zabwino nthawi zambiri zimafuna kufufuza kwina, nthawi zambiri pogwiritsa ntchito njira zofufuzira za endoscopic monga colonoscopy kuti mupeze matenda ndikuwunika ma biopsy.

Mapeto

Mwachidule, mayeso a calprotectin m'chimbudzi ndi chida chamtengo wapatali komanso chothandiza odwala mu gastroenterology yamakono. Amathandiza ngati njira yodziwira kutupa kwa m'matumbo, kuthandiza kusiyanitsa pakati pa IBD ndi IBS ndikuwongolera zisankho zokhudzana ndi kufunikira kwa mayeso owonjezera. Ngati mukukumana ndi zizindikiro zosalekeza za m'mimba, lankhulani ndi dokotala wanu ngati mayeso a calprotectin angakhale gawo loyamba lothandiza paulendo wanu wozindikira matenda.

Mayeso achangu a Baysen atha kuperekamayeso ofulumira a calprotectinzida ngati mukufuna. Takulandirani kuti mutitumizire uthenga ngati muli ndi chidwi.