Pepsinogen IIkorwa kandi igakurwa n'uturemangingo tw'ingenzi tw'agace k'igifu ka oxyntic, naho pepsinogen II igakurwa n'agace k'igifu ka pyloric. Zombi zishyirwa kuri pepsine mu gatuza k'igifu na HCl ikurwa n'uturemangingo twa fundic parietal.

1. Pepsinogen II ni iki?
Pepsinogen II ni imwe muri poroteyine enye za aspartike: PG I, PG II, Cathepsin E na D. Pepsinogen II ikorerwa cyane cyane mu gice cy'umuyoboro wa Oxyntic gland mu gifu, mu gice cy'igifu n'igice cy'imbere mu nda. Isohoka cyane cyane mu gice cy'igifu no mu nzira z'amaraso.
2. Ni ibihe bice bigize pepsinogen?
Pepsinogens zigizwe n'urunigi rumwe rwa polypeptide rufite uburemere bwa molekile bugera ku 42.000 Da. Pepsinogens zikorwa kandi zigakurwa ahanini n'uturemangingo tw'igifu cy'umuntu mbere yuko zihindurwamo enzyme ya proteolytic pepsin, ikaba ari ingenzi mu mikorere y'igogora mu gifu.
3. Ni irihe tandukaniro riri hagati ya pepsin na pepsinogen?
Pepsin ni enzyme yo mu gifu ifasha mu gusya poroteyine ziboneka mu biribwa. Uturemangingo tw’igifu dusohora pepsin nk’umusemburo udakora witwa pepsinogen. Uturemangingo tw’igifu dusohora aside hydrochloric igabanya pH y’igifu.

Agakoresho ko gusuzuma Pepsinogen I/ PepsinogenII (Isuzuma ry’ubudahangarwa bw’umubiri)ni ikizamini cya fluorescence immunochromatographic cyo gupima PGI / PGII mu maraso y'umuntu cyangwa mu maraso, gikoreshwa cyane cyane mu gusuzuma imikorere y'uturemangingo tw'uturemangingo tw'igifu n'indwara y'uturemangingo tw'igifu mu buvuzi.

Murakaza neza kuri terefone kugira ngo mumenye byinshi.