Chii chinonzi Calprotectin?

Calprotectin ipuroteni inowanikwa mumuviri wako, kunyanya mukati merudzi rwemasero machena eropa anonzi neutrophil. Masero aya chikamu chemuviri wako wekudzivirira muviri uye anomhanyira kunzvimbo dzine kuzvimba kana hutachiona. Kana paine kuzvimba muura, ma neutrophils aya anotanga kushanda uye anoburitsa calprotectin. Nokudaro, huwandu hwe calprotectin musampuli yetsvina hunoenderana zvakananga nehuwandu hwekuzvimba mudumbu (GI) tract.

Sei Bvunzo Yaitwa?

Chikonzero chikuru chekuongororwa kwecalprotectin ndechekubatsira vanachiremba kusiyanisa pakati pemhando mbiri huru dzematambudziko emudumbu:

1. Chirwere cheInflammatory Bowel Disease (IBD): Izvi zvinosanganisira zvirwere zvakaita seCrohn's disease uye ulcerative colitis, apo masoja emuviri anorwisa zvisizvo jira remukati medumbu, zvichikonzera kuzvimba kusingaperi.
2. Irritable Bowel Syndrome (IBS): Ichi chirwere chinokonzerwa nekushanda kwenhengo dzemudumbu umo ura hunonzwa husina kugadzikana uye hunokonzera zviratidzo zvakaita sekurwadza kwedumbu nekuzvimba, asi hapana kuzvimba kana kukuvara kunoonekwa.

Zviratidzo zveIBD neIBS—zvakadai sekurwadziwa mudumbu, manyoka anogara achiitika, uye kuzvimba—zvinogona kufanana zvikuru. Kuongororwa kwecalprotectin kunoshanda se "chiratidzo chekuzvimba" chinobatsira kuratidza vanachiremba nzira chaiyo.

Bvunzo Inoitwa Sei?

Bvunzo iri nyore kwazvo uye haipindi muropa. Inoda sampuro diki yetsvina, yaunotora kumba uchishandisa kit yakapihwa nachiremba wako kana kiriniki. Sampuro yacho inozotumirwa kurabhoritari kuti iongororwe. Ikoko, mainjiniya vanoyera huwandu hwecalprotectin mutsvina, inowanzoonekwa muma microgram pa gram (µg/g).

Zvinorevei Zvinoguma Zvaitika?

Mwero Wakajairika/Wakaderera: Mhedzisiro iri mukati mehuwandu hwakajairika (kazhinji pasi pe50 µg/g, asi chiyero chaicho chinogona kusiyana zvichienderana nerabhoritari) inoratidza zvakasimba kuti kuzvimba kuri kushanda muura hakugoneke. Izvi zvinotsigira kuongororwa kwechirwere chisina kuzvimba chakadai seIBS.
High Level: Kuwanda kwe calprotectin kunoratidza kuti kuzvimba kuripo mu GI tract. Izvi zvinoda kuongororwa kwakawanda kuti zvionekwe kuti chii chinokonzera. Kunyange zvazvo chiri chiratidzo chakasimba cheIBD, kuwanda kwacho kunogonawo kuitika mune zvimwe zvirwere zvakaita sehutachiona hwebhakitiriya, colitis, kana kunyange kenza yemuura. Saka, hachisi chishandiso chekuongorora chirwere chakati asi gwara rakakosha.
Kune Vanhu Vanozivikanwa NeIBD: Bvunzo iyi inoshandiswawo kutarisa varwere vakatoonekwa kuti vane Crohn's kana colitis. Kuongorora huwandu hwecalprotectin nguva dzose kunobatsira vanachiremba kuona kana kurapwa kuri kushanda, kana chirwere chiri kudzika, kana kana kuputika kuri kutanga, dzimwe nguva kunyange zviratidzo zvisati zvaonekwa.

Mabhenefiti uye Kuganhurirwa

Mabhenefiti:
Hazvipindi: Hapana tsono kana maskopu anodiwa pakuongororwa kwekutanga.
Chishandiso Chinobatsira Chekuvhiya: Chinobatsira zvinobudirira kupatsanura zvirwere zvekuzvimba kubva kune zvisina kuzvimba, zvichideredza kudiwa kwenzira dzisina kukodzera dzekurapa dzakadai secolonoscopy kune varwere veIBS.
Yakanakira Kuongororwa: Inopa chiyero chakajeka chekuzvimba nekufamba kwenguva.

Miganhu:
Hazvina Kunanga: Zvinoratidza kuzvimba asi hazvizivi chikonzero chaicho kana nzvimbo yacho.
Zvinogona Kuva Nezviratidzo Zvenhema: Kuwanda kwemishonga kunogona kuonekwa kana munhu akashandisa NSAID, mamwe hutachiona hwemudumbu, kana kuti vakwegura.
Kutevera Kunodiwa: Mhedzisiro yepamusoro inowanzoda kuongororwa kwakawanda, kazhinji ne endoscopic nzira dzakadai se colonoscopy kuti iongororwe nemaziso uye kutora biopsy.

Mhedziso

Muchidimbu, bvunzo ye calprotectin yetsvina chishandiso chinokosha uye chinobatsira varwere mukurapa kwegastroenterology yemazuva ano. Inoshanda senzira yekutanga yekuongorora kuzvimba kwemudumbu, ichibatsira kusiyanisa pakati peIBD neIBS uye ichitungamira sarudzo dzekuti bvunzo dzakawanda dzinoda kuongororwa. Kana uine zviratidzo zvekugaya zvekudya zvinoramba zviripo, taura nachiremba wako nezvekuti bvunzo ye calprotectin ingave danho rekutanga rinobatsira here murwendo rwako rwekuongorora chirwere.

Isu Baysen rapid test tinogona kupabvunzo yekukurumidza ye calprotectinKit kana uchida. Tinokugamuchirai kuti mutibate kana muine chido.