Pepsinogen IWaxaa sameeya oo soo daaya unugyada ugu muhiimsan ee gobolka qanjidhada oksaydhka ee caloosha, pepsinogen II-na waxaa soo daaya oo soo daaya gobolka pyloric ee caloosha. Labadaba waxaa lagu kiciyaa pepsins-ka ku jira lumen-ka caloosha iyadoo la adeegsanayo HCl oo ay soo daayaan unugyada fundic parietal.

1. Waa maxay pepsinogen II?
Pepsinogen II waa mid ka mid ah afar borotiin oo aspartic ah: PG I, PG II, Cathepsin E iyo D. Pepsinogen II waxaa inta badan lagu soo saaraa xuubka qanjirka Oxyntic ee caloosha, caloosha iyo duodenum. Waxaa inta badan lagu soo daayaa lumen-ka caloosha iyo wareegga dhiigga.
2. Waa maxay qaybaha pepsinogen?
Pepsinogens waxay ka kooban yihiin hal silsilad polypeptide ah oo leh miisaan molecular ah oo qiyaastii ah 42,000 Da. Pepsinogens waxaa sameeya oo soo daaya inta badan unugyada ugu muhiimsan caloosha ee caloosha aadanaha ka hor inta aan loo rogin enzyme proteolytic pepsin, kaas oo muhiim u ah hababka dheefshiidka ee caloosha.
3. Waa maxay faraqa u dhexeeya pepsin iyo pepsinogen?
Pepsin waa ensaym caloosha ah oo u adeega dheefshiidka borotiinnada laga helo cuntada la cuno. Unugyada ugu waaweyn ee caloosha ayaa soo saara pepsin oo ah zymogen aan firfircoonayn oo loo yaqaan pepsinogen. Unugyada Parietal ee ku jira xuubka caloosha ayaa soo saara aashitada hydrochloric taasoo hoos u dhigta pH-ga caloosha.

Qalabka Baadhista ee Pepsinogen I/ PepsinogenII (Fluorescence Immuno Antibiotic)waa baaritaan immunochromatographic fluorescence ah oo loogu talagalay ogaanshaha tirada ee PGI/PGII ee serum-ka aadanaha ama balaasmaha, waxaana inta badan loo isticmaalaa in lagu qiimeeyo shaqada unugyada qanjidhada oksijiinta caloosha iyo cudurka qanjidhada caloosha ee fundus mucinous ee kiliinikada.

Kusoo dhawoow xiriir si aad u hesho faahfaahin dheeraad ah.