Ukuvula Ideshibhodi Yesifo Sikashukela: UkuqondaI-HbA1c, I-insulin, futhiI-C-Peptide

Ekuvimbeleni, ekuxilongeni nasekulawuleni isifo sikashukela, izinkomba ezimbalwa ezibalulekile embikweni Welebhu zibalulekile. Ngaphandle koshukela wegazi owaziwayo wokuzila ukudla kanye ne-postprandial blood glucose,I-HbA1c, i-insulin, futhi I-C-peptidefuthi badlale indima ebalulekile. Benza njengabaseshi abathathu, ngamunye enobuchwepheshe bakhe, beveza iqiniso mayelana nendlela umzimba osebenza ngayo ushukela wegazi ngokwemibono ehlukene.

1.I-Glycosylated Hemoglobin A1c (HbA1c): “Irekhoda Yesikhathi Eside” Yeglucose Yegazi

Ungacabanga ngakho "njengekhadi lombiko weshukela elimaphakathi" ezinyangeni ezi-2-3 ezedlule. I-hemoglobin emangqamuzaneni abomvu egazi ihlangana ne-glucose egazini—inqubo ebizwa ngokuthi i-glycation. Uma izinga likashukela liphezulu, likhulu nenani le-glycation.

Imisebenzi yayo eyinhloko yilezi:

• Ukuhlola Ukulawulwa KweGlucose Yegazi Yesikhathi eside: Ngokungafani nokuguquguquka kwesikhashana kumazinga eglucose egazini,I-HbA1cikhombisa ngokuzinzile isimo se-glucose esegazini emasontweni ayi-8-12 edlule futhi iyindinganiso eyigolide yokuhlola ukusebenza kahle kwemithi yokwelapha isifo sikashukela.
• Ukusiza Ekuxilongeni Kwesifo Sikashukela: Ngokwezindinganiso ze-WHO, i I-HbA1cIleveli ≥ 6.5% ingasetshenziswa njengendlela eyodwa yokuhlonza isifo sikashukela.

Ngamafuphi, uma ukuzila kanye noshukela wegazi wangemva kokudla "kuyizithombe" zesikhashana ngesikhathi,I-HbA1c"idokhumentari," ekhombisa isithombe esiphelele sokulawula kwakho ushukela wesikhathi eside.

2. I-insulin ne-C-Peptide: I-Golden Partner ye-Pancreatic Function

Ukuze siqonde imbangela yezinkinga zikashukela egazini, kufanele sibheke umthombo—umsebenzi wamaseli we-pancreatic beta. Yilapho "amawele"I-insulinfuthiI-C-Peptide, Ngena.

• I-insulin: Ikhiqizwe amaseli e-beta e-pancreatic, iwukuphela kwehomoni elehlisa ushukela wegazi. Isebenza “njengokhiye,” evula umnyango wengqamuzana futhi ivumele ushukela osegazini ukuba ungene engqamuzaneni futhi uguqulwe ube amandla.
• I-C-Peptide:Le nto ekhiqizwa ngasikhathi sinye futhi ngamanani alinganayo ne-insulin ngamaseli e-beta. Ayinawo umsebenzi wokwehlisa ushukela wegazi ngokwawo, kodwa “iwufakazi othembekile” kuwoi-insulinukukhiqiza.

Ngakho-ke, kungani uhlola kokubili ngesikhathi esisodwa?

Inzuzo eyinhloko ukuthi I-C-peptideizinzile futhi inengxenye yempilo ende kune-insulin, eyivumela ukuthi ibonise ngokunembe kakhudlwana umsebenzi wangempela wokuyimfihlo wama-pancreatic β-cell. Ezigulini ezinesifo sikashukela esivele zelashwa nge-insulin yangaphandle, ama-antibodies e-insulin angase athuthuke, aphazamise ukunemba kokuhlolwa kwe-insulin.I-C-peptide, nokho, akukuthinti lokhu, ngaleyo ndlela kuba inkomba enokwethenjelwa yokuhlola umthamo wesiguli wokukhishelwa kwe-insulin.

3. Abathathu Ekhonsathini: Isithombe Esiphelele

Emisebenzini yomtholampilo, odokotela bahlanganisa lezi zinkomba ezintathu ukuze bakhe iphrofayili ecacile ye-metabolic:

1. Ukwehlukanisa Uhlobo Lwesifo Sikashukela:

• Esigulini esinesifo sikashukela esitholakele, siphansi kakhului-insulinfuthiI-C-peptideamazinga akhombisa ukuntula okukhulu ekukhiqizweni kwe-insulin, okungenzeka ukuthi akuhlukanisa njengesifo sikashukela sohlobo 1.
• If i-insulin futhi I-C-peptideamazinga ajwayelekile noma aphakeme, kepha ushukela wegazi uhlala uphezulu, kuphakamisa ukumelana ne-insulin, isici esijwayelekile sohlobo 2 sikashukela.

2. Ukuhlola Umsebenzi We-Pancreatic & I-insulinUkumelana:

• I i-insulin / I-C-peptide i-release test” ibona izinguquko eziguquguqukayo zalezi zinkomba ngemva kokuphuza iziphuzo ezinoshukela, ezingasiza ekutholeni amandla okugodla kanye nomfihlo wamaseli e-pancreatic β.
• Phezulu i-insulinfuthi phezulu I-C-peptideamazinga ahambisana noshukela ophezulu wegazi awubufakazi obuqondile bokumelana ne-insulin.

3. Izinhlelo Zokwelapha Eziqondisayo:

• Kubantu abanesifo sikashukela soHlobo 2 abanomsebenzi wama-pancreas olondekile, imishanguzo ethuthukisa ukumelana ne-insulin ingase ibe ukukhetha kokuqala.
• Ezigulini ezicishe zikhathale ukusebenza kwe-pancreatic, ukwelashwa kwe-insulin kufanele kuqalwe kusenesikhathi.

Isifinyezo

• I-HbA1c ibonisa "imiphumela" yokulawula ushukela wegazi isikhathi eside
• I-insulinfuthiI-C-Peptidekuveza “ikhono” kanye “nokusebenza kahle” kwendlela yokulawula ushukela emzimbeni wakho.
• IGlucose yegazi ikhombisa “isimo” somzimba wakho samanje.

Ukuqonda ukubaluleka kwalezi zimpawu ezintathu kuvumela ukuqonda okujulile kwesifo sikashukela. Kukunika amandla okuba nezingxoxo ezinolwazi oluthe xaxa nodokotela wakho futhi nisebenze ndawonye ukuze nisungule izinhlelo zokuqapha eziqondene nawe kanye nezokwelapha zokuphathwa kwezempilo okunembayo, okungokwesayensi.

Isiphetho

I-We Baysen Medical ihlale igxile kumasu okuxilonga ukuze sithuthukise izinga lempilo. Senze izinkundla zobuchwepheshe ezi-5- i-Latex, igolide eli-colloidal, i-Fluorescence Immunochromatographic Assay, i-Molecular, i-Chemiluminescence Immunoassay, YethuIkhithi yokuhlola ye-HbA1c,Ikhithi yokuhlola i-insulin ,Ikhithi yokuhlola i-C-peptidezisebenza kalula futhi zingathola umphumela wokuhlolwa emizuzwini eyi-15