Ko te fecal calprotectin (FC) he pūmua here-konupūmā 36.5 kDa e hanga ana i te 60% o ngā pūmua cytoplasmic neutrophil, ā, ka kohia, ka whakahohehia i ngā wāhi mumura o te puku, ka tukuna ki roto i ngā paru.

He maha ngā āhuatanga koiora o te FC, tae atu ki ngā mahi patu huakita, ārai mate, me te ārai tipu. Ina koa, ko te aroaro o te FC e pā ana ki te hekenga o ngā neutrophils ki te ara kai. Nō reira, he tohu whai hua mō te mumura o te puku hei whakatau i te aroaro me te kaha o te mumura i roto i te puku.

E whā noa iho ngā hikoinga e hiahiatia ana hei whakawhanake mai i te mumura o te puku ki te mate pukupuku: te mumura o te puku -> ngā polyp o te puku -> adenoma -> te mate pukupuku o te puku. He maha ngā tau, he tekau tau rānei te roa o tēnei tukanga, ā, he nui ngā whai wāhitanga mō te tirotiro wawe i ngā mate o te puku. Heoi, nā te mea he tokomaha te hunga kāore e aro ki te tirotiro wawe, he maha ngā mate pukupuku o te puku ka kitea i te wā kua tino matatau.

E ai ki ngā raraunga whai mana i te kāinga me tāwāhi, ko te reiti oranga mō ngā tau e 5 o te mate pukupuku koroni i te wā tōmua ka eke ki te 90% ki te 95%. Mena he carcinoma in situ (te wā tōmua), e tata ana te reiti whakaora ki te 100%. Ko te reiti oranga mō ngā tau e 5 o te mate pukupuku koroni i te wā tōmua he iti iho i te 10%. E whakaatu kaha ana ēnei raraunga he mea nui te tirotiro wawe hei whakapai ake i te oranga me ngā reiti whakaora mō ngā tūroro e pāngia ana e te mate pukupuku koroni. I tēnei wā, kua whakaarohia e ētahi tohunga me tirotiro wawe te hunga noa mō te mate pukupuku koroni i muri i te 40 tau te pakeke, ā, me tirotiro wawe te hunga he hītori whānau, he take mōrearea rānei.

Pūmua kimi CalprotectinHe hua kore mamae, kāore e pokanoa, he ngāwari ki te whakahaere e whakamahia ana hei aromatawai i te nui o te mumura o te puku, hei āwhina hoki i te tautuhi i ngā mate e pā ana ki te mumura o te puku (mate mumura o te puku, adenoma, mate pukupuku colorectal). Mena he kino te whakamātautau calprotectin, kāore koe e hiahia ki te mahi i te colonoscopy i tēnei wā. Mena he pai te hua o te whakamātautau, kaua e manukanuka rawa. Ko te nuinga o ngā hua i muri i te colonoscopy he whara mua-mate pukupuku pērā i te adenomas. Ka taea te whakahaere pai i ēnei whara mā te wawaotanga wawe.