PFUPISO

Sepuroteni yechikamu cheacute, serum amyloid A inhengo yemapuroteni akasiyana-siyana emhuri yeapolipoprotein, ayo
ine huremu hwemamorekuru hunosvika 12000. Ma cytokine mazhinji anobatanidzwa mukudzora kutaurwa kweSAA
muchikamu chekukurumidza. Zvinokurudzirwa ne interleukin-1 (IL-1), interleukin-6 (IL-6) uye tumor necrosis factor-α
(TNF-α), SAA inogadzirwa nema macrophages akashanda uye fibroblast muchiropa, iyo ine hafu yenguva pfupi yehupenyu hwemasero chete.
inenge maminetsi makumi mashanu. SAA inobatana ne high-density lipoprotein (HDL) muropa nekukurumidza kana yagadzirwa muchiropa, izvo zvinoita kuti
inofanira kuderedzwa neropa, pamusoro pemasero uye mapuroteni ari mukati memasero. Kana paine mamwe mabhakitiriya akasimba uye asingaperi.
kuzvimba kana hutachiona, mwero wekuora kweSAA mumuviri unoderera zviri pachena ukuwo kugadzirwa kwayo kuchikwira,
izvo zvinoita kuti huwandu hweSAA muropa hurambe huchikwira. SAA ipuroteni inorwisa kuzvimba uye inokonzeresa kuzvimba.
chiratidzo chinogadzirwa nehepatocytes. Huwandu hweSAA muropa huchawedzera mukati memaawa mashoma mushure mekunge
kuitika kwekuzvimba, uye kuwanda kweSAA kuchawedzera ka1000 panguva yekurwadziwa kwakanyanya
kuzvimba. Nokudaro, SAA inogona kushandiswa sechiratidzo chehutachiona hwehutachiona kana kuzvimba kwakasiyana-siyana, izvo
zvinogona kubatsira kuongororwa kwekuzvimba uye kutarisa mabasa ekurapa.

Kiti yedu yekuongorora chirwere cheSerum Amyloid A (Fluorescence Immunochromatographic Assay) inoshanda pakuongorora kwakawanda kweantibody ku serum amyloid A (SAA) muropa revanhu/plasma/ropa rose, uye inoshandiswa pakuongorora kuzvimba kana hutachiona zvakanyanya uye kwenguva refu.

Tinokugamuchirai kuti muwane rumwe ruzivo kana muine kufarira.