WHAKARĀPOPOTONGA

Hei pūmua wāhanga whakapeka, nō roto te amyloid A toto i ngā pūmua rerekē o te whānau apolipoprotein, e
he taumaha ngota whanaunga tata ki te 12000. He maha ngā cytokine e whai wāhi ana ki te whakahaere i te whakaaturanga SAA
i roto i te urupare wāhanga whakapeka. Ka whakaohokia e te interleukin-1 (IL-1), te interleukin-6 (IL-6) me te tumor necrosis factor-α
(TNF-α), ka hangaia te SAA e ngā macrophages kua whakahohehia me te fibroblast i roto i te ate, he poto noa te haurua-ora o
tata ki te 50 meneti. Ka tere te hono a te SAA ki te lipoprotein kiato-teitei (HDL) i roto i te toto i te hanganga i roto i te ate, e
me whakahoro e te toto, te mata o te pūtau me ngā protease ā-roto. Mēnā he mate pāwera, he mate mau tonu rānei
mumura, mate pāwera rānei, ka puhoi haere te tere o te pirau o te SAA i roto i te tinana, i te mea ka piki haere te hanga,
e hua ake ai te pikinga tonu o te kukū SAA i roto i te toto. He pūmua wāhanga whakapeka te SAA, ā, he mumura hoki
tohu i hangaia e ngā pūtau ate. Ka piki ake te kukū o te SAA i roto i te toto i roto i ngā haora e rua i muri i te
te puta o te mumura, ā, ka piki ake te kukū o te SAA ki te 1000 ngā wā i te wā o te mumura whakapeka
mumura. Nō reira, ka taea te whakamahi i te SAA hei tohu mō te mate moroiti, ngā momo mumura rānei, e
ka āwhina i te tautuhi i te mumura me te aroturuki i ngā mahi rongoā.

Ka taea te whakamahi i tā mātou Kete Tātaritanga mō te Amyloid A i roto i te toto (Fluorescence Immunochromatographic Assay) hei kimi i te paturopi ki te amyloid A i roto i te toto (SAA) i roto i te tauira toto tangata/plasma/toto katoa, ā, ka whakamahia hei tātaritanga āwhina mō te mumura, te mate pāwera rānei, te mate kino rānei, me te mumura mau tonu, me te kore e kitea.

Nau mai ki te whakapā mai mō ētahi atu kōrero mēnā he hiahia tōu.